News by Subject Biology

Findings from a collaborative clinical trial have generated key insights into how targeted therapy should be used to treat leukemia driven by the Philadelphia chromosome.

A byproduct of glucose called lactate, used by every cell in the body, may also prompt a mutated cell to become cancerous, according to new research from the University of Colorado Anschutz Medical Campus.

The brain is a sort of fortress, equipped with barriers designed to keep out dangerous pathogens. But protection comes at a cost: These barriers interfere with the immune system when faced with dire threats such glioblastoma, a deadly brain tumor for which there are few effective treatments. Yale researchers have found a novel way to circumvent the brain's natural defenses when they're counterproductive by slipping immune system rescuers through the fortresses' drainage system.

In a radical new approach to treat cocaine addition, researchers at the Mayo Clinic are seeking approval for first-in-human studies of a single-dose gene therapy.

Scientists at UCL have identified how a subset of immune cells are activated to kill cancerous cells, a finding in mice which could hold the key to new powerful therapies against cancer.

A breakthrough gene therapy treatment for Haemophilia A has been shown to offer long-term benefits that have already transformed the lives of 13 men in the UK.