A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.
St. Jude Children's Research Hospital scientists have developed a highly efficient method to address a major challenge in biology--identifying the genetic 'switches' that regulate gene expression.
A team of researchers from UCLA, Cedars-Sinai and the Cystic Fibrosis Foundation has developed a first-of-its-kind molecular catalog of cells in healthy lungs and the lungs of people with cystic fibrosis. The findings could help scientists in their search for specific cell types that represent prime targets for genetic and cell therapies for cystic fibrosis.
Researchers at the University of New Hampshire found that to live in hotter more desert-like surroundings, and exist without water, there is more than one genetic mechanism allowing animals to adapt. This is important not only for their survival but may also provide important biomedical groundwork to develop gene therapies to treat human dehydration related illnesses, like kidney disease.
Nanoscope Technologies LLC, a biotechnology company developing gene therapies for treatment of retinal diseases, is featuring multiple scientific presentations highlighting its groundbreaking research on optical gene delivery for vision restoration and OCT-guided electrophysiology platforms for characterization of retinal degeneration and assessment of efficacy of cell-gene therapy at the 2021 ARVO annual (virtual) meeting, May 1-7. Nanoscope's Multi-Characteristics Opsin (MCO) when delivered into cells to reprograms cells to sense ambient light, thus allowing vision restoration in patients with retinal degeneration.
An experimental treatment produced improvements in cognitive function and language in patients with fragile X syndrome, according to study results published on April 29 in Nature Medicine.
A group of researchers has discovered a new approach to cereal plant breeding that takes into account the internal "calculator" of plant seeds that makes them continuously reorganize themselves (global coherence). The approach includes unforeseen and unintended changes in the plant when genetically manipulated by the plant breeders. The researchers expect that the method can be used to improve the world's crops much more efficiently.
Imaging techniques enable decisive step toward development of novel hearing prostheses
What The Study Did: The association of identified SARS-CoV-2 variants and virus groupings with disease severity and patient outcomes is evaluated in this study.
Over the last 60 years, scientists have been able to observe how and when genetic information was replicated, determining the existence a "replication timing program", a process that controls when and in what order segments of DNA replicate. However, scientists still cannot explain why such a specific timing sequence exists. In a study published today in Science, Dr. David Gilbert and his team have answered this 60-year-old question.