Accounting for cell components in saliva increases the reliability of biochemical tests for experience-driven epigenetic changes.
Fat cells can be damaged in a short amount of time when they are exposed to the fatty acid palmitate or the hormone TNF-alpha through a fatty diet, a new study shows. The researchers from Novo Nordisk Foundation Center for Basic Metabolic Research hope this new knowledge may be used to develop new preventive strategies for diabetes.
International research consortium led by researchers from the University of Helsinki, Finland, discovered new information related to a rare form of leukemia called aggressive NK-cell leukemia. Potential new treatment options were found which are highly warranted as currently this disease usually leads to rapid death of patients.
A new study in fat cells has revealed a molecular mechanism that controls how lifestyle choices and the external environment affect gene expression. This mechanism includes potential targets for next-generation drug discovery efforts to treat metabolic diseases including diabetes and obesity.
St. Jude Children's Research Hospital scientists have discovered a fourth gene that can predispose carriers to the most common childhood cancer, expanding the list of genes to include in cancer screening.
The largest study of its kind sheds light on how genes work together to keep cells healthy, paving the way for predicting a person's risk of disease.
Gene editing of bone marrow stem cells in pigtail macaques infected with simian/human immunodeficiency virus (SHIV) significantly reduces the size of dormant 'viral reservoirs' that pose a risk of reactivation. Christopher Peterson of the Fred Hutchinson Cancer Research Center in Seattle, Wash., and colleagues present these findings in PLOS Pathogens.
Americans die of heart or cardiovascular disease at an alarming rate. In fact, heart attacks, strokes and related diseases will kill an estimated 610,000 Americans this year alone. Some medications help, but to better tackle this problem, researchers need to know exactly how the heart and blood vessels stay healthy in the first place.
Humans and chimpanzees recently evolved a more active fight-or-flight response compared to other primates, possibly in response to the threat of warfare. Jung Kyoon Choi of KAIST in Korea, in collaboration with Soojin Yi of Georgia Tech, report these findings in a new study published April 19, 2018, in PLOS Genetics.
A common Great Barrier Reef coral species has enough genetic diversity to survive at least 100 years before succumbing to global warming predicts Mikhail Matz of the University of Texas at Austin and colleagues. They report these findings in a new study published April 19, 2018, in PLOS Genetics.