Need stronger timber, better biofuels or new sources of green chemicals? A systems biology model developed over decades of research led by NC State University will accelerate progress in engineering trees for specific needs.
An international team of researchers led by professor Niklas Arnberg at Umeå University, shows that adenovirus binds to a specific type of carbohydrate that is overexpressed on certain types of cancer cells. The discovery opens up new opportunities for the development of virus-based cancer therapy. The study is published in the latest issue of the scientific journal Proceedings of the National Academy of Sciences.
A multidisciplinary team of scientists share recent advancements in innovative in-vitro cancer biology methods for screening drug-like molecules in cancer tissue relevant models in a new report published online ahead-of-print at SLAS Discovery. Entitled Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening, the report can be accessed for free.
Cancer immune cell therapy has made headlines with astounding successes like saving former US President Jimmy Carter from brain cancer. But immunotherapy has also had many tragic flops. Georgia Tech researchers working to optimize the innovative treatment have implanted a genetic switch that activates T-cells when they are inside of tumors. Remote-control light waves resembling those used in a TV remote combine with gold nanorods to flip the switch.
UConn researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
A silk hybrid material attacks bacteria when illuminated by a green light, thanks to a far-red fluorescent protein researchers transferred to its genetic makeup.
International research consortium led by researchers from the University of Helsinki, Finland, discovered new information related to a rare form of leukemia called aggressive NK-cell leukemia. Potential new treatment options were found which are highly warranted as currently this disease usually leads to rapid death of patients.
Advances in genome sequencing are providing vast amounts of genetic information that researchers are using to explore the plant family tree. This special issue showcases cutting-edge techniques that are providing solutions to challenges in the study of evolution of species (or phylogenetics); issue highlights include an overview of current options for phylogenomic studies, a new natural language processing pipeline, metagenomics pipeline comparisons, and reviews of sequence capture methods and custom pipelines for marker selection.
Scientists at Christiana Care Health System's Gene Editing Institute have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code, according to a new study published today in the CRISPR Journal.
The largest study of its kind sheds light on how genes work together to keep cells healthy, paving the way for predicting a person's risk of disease.