For most of Mikel-Stites' life, he had been nit-picking at the 'science' in science-fiction movies.
Researchers have genetically transformed the Common Primrose (Primula vulgaris) for the first time in a development that could shed light on one of the plant world's most renowned reproductive systems.
Scientists at the University of Würzburg have been able to boost current super-resolution microscopy by a novel tweak. They coated the glass cover slip as part of the sample carrier with tailor-made biocompatible nanosheets that create a 'mirror effect'. This method shows that localizing single emitters in front of a metal-dielectric coating leads to higher precision, brightness and contrast in Single Molecule Localization Microscopy (SMLM). The study was published in the Nature journal Light: Science and Applications.
Scientists at Kyushu University and Tokyo Institute of Technology in Japan have developed a technique that enables analysis of DNA-protein interactions using very small numbers of cells, ranging from 100 to 1,000. Their method could capture previously unexamined epigenomic information, facilitate biomarker discovery and open new avenues for precision medicine.
EPFL researchers have developed a method to observe the electrical activity of neurons by analyzing the behavior of surrounding water molecules. This simple and non-invasive method, which could eliminate the need for electrodes and fluorophores, can be used to monitor the activity within a single neuron or potentially on an entire region of the brain.
Rotator Cuff tears affect 15 percent of 60 year olds and carry a significant social and financial burden. Current operative techniques and repair adjuncts are associated with unacceptably high failure rates, stimulating investigation into novel tissue engineering and regenerative medicine (TERM) approaches in the field of rotator cuff surgery. In this review researchers explore the most recent advances in the field of electrospinning, focussing on proposed tissue-engineered solutions in tendon, specifically the rotator cuff.
Chondral defects caused by tumor, trauma, infection, congenital malformations are very common in clinical trials. It seriously affects the patient's physical function and quality of life. Through this review, the researchers aimed to review the progress of the types and preparation techniques of scaffold materials in cartilage tissue engineering.
A team of researchers developed a novel model of partial bladder outlet obstruction in female swine and used this model to show that even after inducing severe urinary outlet resistance and damage to the bladder, they could achieve significant improvements in bladder capacity through bladder reconstruction using acellular bi-layer silk fibroin grafts.
Researchers from three research institutes in Spain have developed a biotechnological tool to produce, in a very efficient manner, antifungal proteins in the leaves of the plant Nicotiana benthamiana. These proteins are promising biomolecules that could be used to develop new antifungals whose properties and mechanisms of action represent improvements on the existing ones, and which can be applied in diverse fields, including crop and postharvest protection and animal and human health.
The objective of study was to understand the damages induced by toxins in the liver and the intestine as well as the interplay between the miRNome and transcriptome baseline characterization in these tissues in healthy animals under cellular homeostasis.