In a mouse study, researchers used nanotechnology and previous knowledge of a protein pathway to significantly reduce knee cartilage degeneration and pain
Researchers from Skoltech and the University of Texas Medical Branch (US) have shown how optoacoustics can be used for monitoring skin water content, a technique which is promising for medical applications such as tissue trauma management and in cosmetology.
Researchers at RIKEN, Japan successfully created a larger strain of zooplankton by creating mutations with a heavy ion beam, which contributes to improving the survival rate and growth of juvenile fish in aquaculture.
Some organisms evolve an internal switch that can remain hidden for generations until stress flicks it on.
Using data from RNA-folding experiments, the researchers generated the first-ever data-driven movies of how RNA folds as it is made by cellular machinery. By watching their videos of this folding occur, the researchers discovered that RNA often folds in surprising, perhaps unintuitive ways, such as tying itself into knots.
A team of biophysicists set out to tackle the long-standing question about the nature of force generation by myosin, the molecular motor responsible for muscle contraction. The key question they addressed - one of the most controversial topics in the field - was: how does myosin convert chemical energy, in the form of ATP, into mechanical work? The answer revealed new details into how myosin, the engine of muscle and related motor proteins, transduces energy.
In research published today in Integrative Biology, a team of engineers from Rensselaer developed an in vitro -- in the lab -- lymphatic vessel model to study the growth of tumor emboli, collections of tumor cells within vessels that are often associated with increased metastasis and tumor recurrence.
Researchers have developed a highly sensitive technique to quantitatively evaluate the extent of cytoskeleton bundling from microscopic images. Until now, analysis of cytoskeleton organization was typically made by manually checking microscopic images. The new method uses microscopic image analysis techniques to automatically measure the cytoskeleton organization. The researchers expect it to dramatically improve our understanding of various cellular phenomena related to cytoskeletal bundling.
Retinal cells derived from adult human eye stem cells survived when transplanted into the eyes of monkeys, an important early step in the validation of this approach for treating blindness, according to a study by Liu, et al recently published in Stem Cell Reports. The retinal pigment epithelium (RPE), a layer of pigmented cells in the retina, is essential for sustaining normal vision. Blindness due to RPE dysfunction, such as macular degeneration, affects about 200 million people worldwide.
KAIST metabolic engineers presented the bio-based production of multiple short-chain primary amines that have a wide range of applications in chemical industries for the first time. The research team designed the novel biosynthetic pathways for short-chain primary amines by combining retrobiosynthesis and a precursor selection step.