Scientists at Fujita Health University, Japan, have discovered how deficiencies of the IL-36Ra protein -- caused by mutations in the IL36RN gene -- delay wound healing via the flooding of the wound with several types of immune cells. However, by inhibiting the functioning of proteins and the signaling pathways involved in activating the immune system at a wound, this delay can be offset. These findings could aid efforts to develop ways of regulating wound healing in IL36RN mutation-related skin disorders.
Study demonstrates how changes in human genes can reduce SARS-CoV-2 infection and describes a wide array of genes that have not previously been considered as therapeutic targets for SARS-CoV-2.
The Singapore University of Technology and Design, together with Singapore's Tan Tock Seng Hospital, developed a novel 3D printed non-metallic self-locking prosthetic arm for a patient with a forequarter amputation - it is more comfortable, flexible and 20% cheaper than a conventional prosthesis.
Dr Constantino Carlos Reyes-Aldasoro and Dr Cefa Karabag collaborate with the Francis Crick Institute on a novel approach published in the PLoS ONE journal, which significantly reduces the amount of time taken to analyse the cell line named after Henrietta Lacks, an African-American woman whose contribution to medical science was only formally acknowledged decades after her death.
To promote resource sharing and research cooperation for the synthetic biology and molecular breeding of industrial oil-producing microalgae, an international team led by Single-Cell Center (SCC), Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS), has released the "NanDeSyn Database" (http://www.nandesyn.org).
The tiniest amount of DNA is being accurately analysed to identify the origins of old ivory. This clever new technique has the potential to thwart international ivory poachers, by placing the origins of ivory pieces into accurate source locations, thereby identifying specific areas where ivory poachers are actively operating.
Dual-organ system enables the measurement of cardiac toxicity arising from breast cancer chemotherapy. A collaborative team, which includes a group from the Terasaki Institute for Biomedical Innovation, has developed an organs-on-a-chip system that more widely examines the responses of breast cancer and heart tissues to therapeutic breast cancer drugs.
Study using biomimetic fish-like robots shows that swimming closely together offers fish hydrodynamic benefits - research project with participation from University of Konstanz researchers provides first experimental validation of an answer to an old question.
The CRISPR Journal announces the publication of its October 2020 issue.
Researchers develop a new method to isolate specific cells, and in the process find a more robust fluorescent protein.