In an article published in the peer-reviewed SPIE publication Neurophotonics, 'High density functional diffuse optical tomography based on frequency domain measurements improves image quality and spatial resolution,' researchers demonstrate critical improvements to functional Near Infrared Spectroscopy (fNIRS)-based optical imaging in the brain.
Scientists at EPFL have developed a new method to synthesize and screen thousands of macrocyclic compounds, a family of chemicals that are of great interest in the pharmaceutical industry. The study is published in Science Advances.
Biomedical engineers at Duke University have discovered that an adenosine receptor called A2B can be pharmaceutically activated to reverse bone degradation caused by osteoporosis in mouse models of the disease.
Study assembles canola root's dose-response curves for nitrogen sources.
Like many women who develop a particular type of breast cancer, the same gene -- HER2 -- also appears to be the cause of lung cancer in many dogs. TGen and Ohio State found that neratinib -- a drug that has successfully been used to battle human breast cancer -- might also work for many of the nearly 40,000 dogs in the US that annually develop the most common type of canine lung cancer, known as CPAC.
The National Institute of Environmental Health Sciences has awarded Ohio University scientists Shiyong Wu and Lingying Tong a five-year $1.7 million grant to advance research on a potential prevention and treatment for non-melanoma skin cancers.
Bioengineers and dentists from the UCLA School of Dentistry have developed a new hydrogel that is more porous and effective in promoting tissue repair and regeneration. Once injected in a mouse model, the new hydrogel is shown to induce migration of naturally occurring stem cells to better promote bone healing. Current experimental applications using hydrogels and stem cells introduced into the body or expensive biological agents can come with negative side effects.
An international team led by NTU Singapore has grown 'miniature kidneys' in the laboratory that could be used to better understand how kidney diseases develop in individual patients. These kidney organoids were grown outside the body from skin cells derived from a single patient who has polycystic kidney disease. This method has paved the way for tailoring treatment plans specific to each patient, which could be extended to a range of kidney diseases.
Dr. Mihue Jang's group at the Korea Institute of Science and Technology(KIST) announced that they have developed a new gene editing system that could be used for anticancer immunotherapy through the simultaneous suppression of proteins that interfere with the immune system expressed on the surface of lymphoma cells and activation of cytotoxic T lymphocyte, based on the results of joint research conducted with Prof. Seokmann Hong's group at Sejong University
The effectiveness of current anti-clotting medication can be limited due to the risk of complications. This is driving a need for alternatives that can both prevent the formation of blood clots and reduce the risk of excessive and life-threatening bleeding. A new biocompatible lab-on-a-chip could help accelerate the discovery and development of new anti-clotting therapies, with automated processes that can achieve in a few minutes what could take days in a full-sized lab.