Radio-resistance in bacteria first evolves through the adaptation of DNA repair mechanisms, however as evolution continues more mutations accumulate, and more cellular metabolic processes are affected. It is not yet clear which panel of mutations provides high-level resistance. The study shows that acquisition of radio-resistance via evolution is possible independent of other mechanisms like extreme dryness resistance (desiccation).
Artificial intelligence can speed the development of 3D-printed bioscaffolds that help injuries heal, according to researchers at Rice University.
Researchers have created a machine-learning algorithm that can pick up on subtle signs of osteoarthritis - too abstract to register in the eye of a trained radiologist - on an MRI scan taken years before symptom onset.
While the power conversion efficiency of perovskite solar cells (PVSCs) has already greatly improved in the past decade, the problems of instability and potential environmental impact are yet to be overcome. Recently, scientists from City University of Hong Kong (CityU) have developed a novel method which can simultaneously tackle the leakage of lead from PVSCs and the stability issue without compromising efficiency, paving the way for real-life application of perovskite photovoltaic technology.
Researchers have found a way to send tiny, soft robots into humans, potentially opening the door for less invasive surgeries and ways to deliver treatments for conditions ranging from colon polyps to stomach cancer to aortic artery blockages.
A multi-disciplinary research collaboration which was led by Harvard's Wyss Institute for Biologically Inspired Engineering and the Massachusetts Institute of Technology (MIT), created a field-applicable, ultrasensitive diagnostic assay that specifically detects DNA sequences from all Plasmodium species in symptomatic and asymptomatic malaria. The new malaria diagnostic method combines an optimized 10-minute rapid sample preparation protocol with the CRISPR-based SHERLOCK system to enable highly specific and sensitive Plasmodium detection in another 60 minutes in simple reporter devices.
In March, researchers in the Department of Biomedical Engineering-- a shared department in the schools of Dental Medicine, Medicine, and Engineering--began to develop a new, low-cost, CRISPR-based diagnostic platform to detect infectious diseases, including HIV virus, the novel coronavirus (SARS-CoV-2). Today, the method is one step closer to being a cutting-edge diagnostics technology for rapid detection of infectious diseases.
Addressing concerns about gene drive releases in the wild, UC San Diego scientists and their colleagues have developed two new genetic systems that halt or eliminate gene drives after release. Created in fruit flies, the e-CHACRs and ERACRs are powerful gene drive control mechanisms that were meticulously developed and tested at the genetic and molecular levels.
How much time does a brain need to learn a new word? A team of Skoltech researchers and their colleagues monitored changes in brain activity associated with learning new words and found that cortical representations of the sound and meaning of these words may form in just 1 to 2 hours after exposure without any night's sleep consolidation, as earlier research suggested. This research has implications for diagnosing speech disorders and improving the efficiency of learning.
A CRISPR-based diagnostic for the SARS-Cov-2 virus can produce results in less than an hour with similar accuracy as the standard PCR test now used. Development of the Covid-19 test was led by researchers at MIT and the Broad Institute of MIT and Harvard.