Through a few clever molecular hacks, researchers at Columbia University Medical Center have converted a natural bacterial immune system into a microscopic data recorder, laying the groundwork for a new class of technologies that use bacterial cells for everything from disease diagnosis to environmental monitoring.
Power stored in electric cars could be sent back to the grid -- thereby supporting the grid and acting as a potential storage for clean energy -- but it will only be economically viable if we upgrade the system first. In a new paper in Energy Policy, two scientists show how their seemingly contradictory findings actually point to the same outcome and recommendations.
Cardiac fibrosis involves an increase of connective tissue in the cardiac muscle, causing a loss of function. Researchers at the Technical University of Munich (TUM) have now discovered that fibrosis occurs less frequently when microRNA 29 (miR-29) is suppressed in cardiac muscle cells. Older studies had suggested that it was in fact low levels of miR-29 that caused fibrosis. The new insights point to potential new approaches for developing drugs against fibrotic diseases.
Tiny robots could be developed to diagnose illness and deliver treatments in hard-to-reach parts of the human body.
Oftentimes, kids with congenital heart defects only have heart failure on one side of their heart. That's why Boston Children's Hospital researchers and collaborators have developed a soft robotic system that can provide isolated support to the right or left ventricle. The proof-of-concept device was reported in Science Robotics today.
Researchers at Duke University have discovered that reducing the use of antibiotics will not be enough to reverse the growing prevalence of antibiotic resistance because bacteria are able to share the ability to fight antibiotics by swapping genes between species. They also show, however, that there are ways to disrupt the gene-sharing process and perhaps reverse antibiotic resistance.
A team of bioengineers and bioinformaticians at the University of California San Diego have discovered how the environment surrounding a tumor can trigger metastatic behavior in cancer cells. Specifically, when tumor cells are confined in a dense environment, the researchers found that they turn on a specific set of genes and begin to form structures that resemble blood vessels.
Human genome editing, 3-D-printed replacement organs and artificial photosynthesis - the field of bioengineering offers great promise for tackling the major challenges that face our society. But as a new article out today highlights, these developments provide both opportunities and risks in the short and long term.
Inflammation processes are responsible for the failure of insulin production in diabetes patients. The patients' own immune systems can contribute to treatment of this disease: researchers at the University of Basel and University Hospital Basel have found a feedback mechanism that could help maintain insulin production in overweight sufferers, as they report in the journal Immunity.
University of Colorado Boulder researchers have discovered a potent, drug-like compound that could someday revolutionize treatment of rheumatoid arthritis and other autoimmune diseases.