Pancreatic Cancer Collective-funded research (Lustgarten Foundation and Stand Up To Cancer) from Dr. Tony Hunter (Salk Institute) and the SU2C-CRUK-Lustgarten Pancreatic Cancer Dream Team has found the presence of a key protein (Leukemia Inhibitory Factor or LIF) in PDAC microenvironment may be an exploitable treatment target to slow tumor progression or metastasis and may lead to the development of new targeted strategies for pancreatic cancer therapy.
Lustgarten Foundation and SU2C offer comments on research describing a new combination drug therapy demonstrating promise for patients with pancreatic cancer. This research is the foundation for a Pancreatic Cancer Collective New Therapies Challenge Grant to Dr. Martin McMahon (Huntsman Cancer Institute). The Collective offers this video of Dr. McMahon and David Tuveson, MD, PhD commenting.
Publish or perish is an adage with particular sting for women and other underrepresented scholars prone to not getting deserved credit on scientific papers. F&W scientists will provide perspective and pointers at the upcoming AAAS Annual Meeting.
An analysis of nearly 24,000 grant applications at the Canadian Institutes of Health Research finds that women are less successful in receiving funding if reviewers are explicitly asked to review the principal investigator, rather than when they are asked to assess the quality of the science. The study is published as part of a special issue of The Lancet on advancing women in science, medicine and global health.
Researchers have combined the largest description of ST3GAL5 (GM3 synthase) deficiency using detailed natural history data from 104 individuals of Amish ancestry born between 1986 and 2017 with a definite or probable diagnosis of ST3GAL5 deficiency. The study examined objective measures of biochemistry, auditory function, brain development, and caregiver burden. GM3 synthase is encoded by ST3GAL5, and is essential for synthesis of the most biologically relevant gangliosides in mammals.
The paper looks at the different benefits stars and non-stars bring, both to the task at hand and to the collaborators' ability to come up with breakthrough ideas in the future.
Immigrant academics play a critical role in the UK's international and national collaborations that bring social and economic benefits beyond academia, shows a new study of the public engagement activities of the UK's native-born and international academics.
New research publishing Nov. 20 in the open-access journal PLOS Biology from Joshua Wallach, Kevin Boyack, and John Ioannidis suggests that progress has been made in key areas of research transparency and reproducibility. The authors randomly sampled biomedical journal articles published between 2015 and 2017 and assessed measures of reproducibility and transparency.
Army researchers have developed for the first time an analytic model to show how groups of people influence individual behavior.
A recent study assessing the relationship between nursing specialty certification rates and surgical site infections (SSI) provides an innovative option for future research exploring relationships between nursing and hospital procedures and medical and/or surgical adverse events.