University at Buffalo researchers are reporting an advancement of a chemical sensing chip that could lead to handheld devices that detect trace chemicals -- everything from illicit drugs to pollution -- as quickly as a breathalyzer identifies alcohol.
Published research shows a new "Trojan horse" approach that produces strong antidotal efficacy in treating lethal botulism.
Preclinical data published in Science Translational Medicine showed that post-symptomatic administration of Cyto-111 produced antidotal rescue in three animal species following a lethal botulism challenge. Study authors concluded, " atoxic BoNT derivatives can be harnessed to deliver therapeutic protein moieties to the neuronal cytoplasm where they bind and neutralize intracellular targets in experimental models. The generalizability of this platform might enable delivery of antibodies and other protein-based therapeutics to previously inaccessible intraneuronal targets."
This method allows users to identify legal versus illegal gamma rays. Detectors like these are critical for national security, where they're used to detect illegal nuclear materials smuggled across borders and aid in nuclear forensics, as well as in medical diagnostics imaging.
To develop effective therapeutics against pathogens, scientists need to first uncover how they attack host cells. An efficient way to conduct these investigations on an extensive scale is through high-speed screening tests called assays.
Researchers at Osaka University created a machine-learning system to identify single viral particles that cause respiratory diseases, including coronavirus, using silicon nanopores. The method does not require labels or reagents and may lead to much cheaper and rapid detection of viruses that cause infectious diseases such as COVID-19.
In new research appearing in the journal mBio, Arvind Varsani and his colleagues investigate a recently discovered class of viruses that have taken the characteristic versatility of the viral world to new heights. Referred to as cruciviruses, these minute forms reveal a fusion of components from both RNA and DNA viruses, proving that these previously distinct genomic domains can, under proper conditions, intermingle, producing a hybrid or chimeric viral variant.
The uncertainty and confusion caused by the COVID-19 pandemic is being "widely exploited by terror groups for spinning a plethora of sinister schemes", which could lead to a new tide of violence against people and governments.
People who have been exposed to chemical warfare agents (CWAs) feel uncertain, decades after the exposure, about their survival and ability to build a family, a University of Gothenburg study shows. Women are more severely affected than men.
A study carried out from the Turin university in collaboration with the Advanced Energy Technology Institute CNR-ITAE and published on the journal Scientific Reports, suggest a low cost technology to store heat during the summer and use it during the winter, thus saving in fossil fuels.