The bottom of the Baltic Sea is home to large quantities of sunken munitions, a legacy of the Second World War -- and often very close to shore. Should we simply leave them where they are and accept the risk of their slowly releasing toxic substances, or should we instead remove them, and run the risk of their falling apart -- or even exploding?
A new gas detector, developed by researchers at UBC's Okanagan campus, enables highly accurate odour analysis for so many different applications it has been nicknamed the 'artificial nose.' Researchers in the School of Engineering have developed a state-of-the-art microfluidic gas detector that can detect small traces of gases quickly and efficiently. It has a number of potential uses including environmental monitoring, food and beverage quality assessments, and biological and chemical analytical systems.
Microneedles able to draw relatively large amounts of interstitial fluid -- a liquid that lurks just under the skin -- opens new possibilities. Previously, microneedles -- tiny, hollow, stainless steel needles -- have drained tiny amounts of interstitial fluid needed to analyze electrolyte levels but could not draw enough fluid to make more complicated medical tests practical. The new method's larger draws could be more effective in rapidly measuring exposure to chemical and biological warfare agents as well as diagnosing cancer and other diseases.
Familial hypercholesterolemia is a hereditary genetic disorder predisposing in premature atherosclerosis and cardiovascular complications.The main gap of evidence remains the lack of longitudinal follow up studies investigating cardiovascular outcomes, side effects, and effectiveness of treatment starting from childhood. Evidence would be expected in the near future by cohort and registry studies.
Monoamine oxidase inhibitors are potential drug candidates within therapeutics of different neuropsychological and neurodegenerative disorders including anxiety, depression and Parkinson's disease. Our findings revealed a good correlation between experimental MAO inhibition and docking score by computational studies. Notably, the compounds with remarkable MAO inhibitory potential were also observed as potential antioxidants.
Resolution of both supply and cost issues allows clinical research to proceed through clinical trials and potentially produce one or more effective therapies for cancer or infectious diseases that could benefit the public.NorthStar Medical Technologies, LLC, has investigated several routes that could lead to commercial scale production of actinium-225.The outlook for future supplies of actinium-225 from multiple sources to support clinical needs is encouraging.
The huge amounts of epigenetic data coming from biological experiments and clinic, machine learning can help in detecting epigenetic features in genome, finding correlations between phenotypes and modifications in histone or genes, accelerating the screen of lead compounds targeting epigenetics diseases and many other aspects around the study on epigenetics, which consequently realizes the hope of precision medicine.
Synthetic psychoactive drugs have become a serious public health threat in recent years. This is particularly true of the fentanyls, a large family of synthetic opioids, which can be up to 10,000 times more potent than morphine. Synthetic opioids are highly addictive and, because of their potency, often prove fatal: among the roughly 72,000 drug overdose deaths in the US in 2017, some 30,000 were related to synthetic opioids.
About 3 million people in the US are diagnosed every year with bipolar disorder, a psychiatric condition characterized by dramatic shifts in mood from depression to mania. Currently, the standard treatment includes a combination of psychotherapy and prescription medications such as mood stabilizers and antipsychotics.
A team of researchers has developed an algorithm for predicting the effect of an external electromagnetic field on the state of complex molecules. The new algorithm, presented in a paper in The Journal of Chemical Physics, enables researchers to look inside large polyatomic molecules, observe and potentially control electron motion therein.