A simple instruction to change your thinking as mealtime approaches can help cut calories, according to new research from the University of Tübingen, Germany. By encouraging study participants to concentrate on different types of information when planning their meal, the experimenters saw portion sizes shift. Adopting a health-focused mindset produced better outcomes than focusing on pleasure or the desire to fill up.
Scientists at Rutgers Brain Health Institute have discovered that a small group of brain cells in the hypothalamus called 'orexin' neurons could be a promising target for medications for controlling binge eating episodes in individuals with obesity. These neurons, named for the chemical messenger they use to communicate with other brain cells, have previously been shown to be important for addiction to several drugs, including cocaine.
A novel drug based on capsaicin, the compound that gives chili peppers their spicy burn, caused long term weight loss and improved metabolic health in mice eating a high fat diet, in new studies from the University of Wyoming School of Pharmacy. The drug, Metabocin, was designed to slowly release capsaicin throughout the day so it can exert its anti-obesity effect without producing inflammation or adverse side effects.
Improved medications for Type 2 diabetes are one step closer thanks to a new discovery reported this week by researchers at the University of Pennsylvania and Syracuse University. By modifying the key ingredient in current diabetes drugs, the researchers produced a compound that was effective for hyperglycemia in animal trials, yet without the most problematic side effects of current drugs.
New research on how cannabis use alters eating behavior could lead to treatments for appetite loss in chronic illness, according to experts at Washington State University. Using a new procedure to dose lab rats with cannabis vapor, the researchers found how the drug triggers hunger hormones. They also identified specific brain regions that shift to 'hungry' mode while under the influence, according to a report they shared this week at the Society for the Study of Ingestive Behavior.
Scientists have long known that RNA encodes instructions to make proteins. The building blocks that comprise RNA--A, U, C, and Gs--form a blueprint for the protein-making machinery in cells. In a new study published in Nature, scientists describe how the protein-making machinery identifies alternative initiation sites from which to start protein synthesis.
An international team of scientists that includes UC Riverside physicist Hai-Bo Yu has imposed conditions on how dark matter may interact with ordinary matter. In the search for direct detection of dark matter, the experimental focus has been on WIMPs, or weakly interacting massive particles, the hypothetical particles thought to make up dark matter. But the research team invokes a different theory to challenge the WIMP paradigm: the self-interacting dark matter model, or SIDM.
Supplementing a single protein found in the spinal cord could help prevent symptoms of Lou Gehrig's disease, according to a new study out of Case Western Reserve University School of Medicine. Researchers found high levels of the protein -- called mitofusion 2 or Mfn2 -- prevented nerve degeneration, muscle atrophy, and paralysis in a mouse model of the disease. Since Mfn2 is often depleted during Lou Gehrig's, the new study suggests supplementing it could be a novel therapeutic approach for the disease.
In today's hyper-connected world, a growing number of nations are acting as 'middlemen' in the seafood supply chain. This makes it increasingly difficult to trace where seafood goes and difficult to anticipate changes in market demand.
Adam Friedman, M.D., professor of dermatology at the GW School of Medicine and Health Sciences, and his team investigated the use of nanotechnology to improve efinaconazole treatment and make it more cost effective.