Researchers from Michigan State University College of Human Medicine and physicians from Spectrum Health have identified for the first time in a human patient a genetic disorder only previously described in animal models.
Working in a competitive industry fosters a greater level of trust amongst workers, finds a new study from the University of British Columbia, Princeton University and Aix-Marseille University, published today in Science: Advances.
New Michigan State University research shows that bosses struggle, like the rest of us, to keep up with email demands. What makes managers unique is that email traffic prevents them from being effective leaders and threatens employee performance.
More than half of early-career scientists who received their first research project (R01) grants from the National Institute of Allergy and Infectious Diseases (NIAID) are successful in obtaining subsequent funding from the National Institutes of Health (NIH), according to a study published September 12 in the open-access journal PLOS ONE by Patricia Haggerty and Matthew Fenton of NIAID, an NIH institute.
Applying a comprehensive analysis of genetic, historical, and archeological factors in two 6th-century barbarian cemeteries, researchers have gleaned new insights into a key era known as the Migration Period that laid the foundation for modern European society. A paper, published today in Nature Communications, seeks to shed new light on how these communities were formed, how people lived, and how they interacted with the local populations they supposedly came to dominate.
You've likely heard of hot hands or hot streaks -- periods of repeated successes -- in sports, financial markets and gambling. But do hot streaks exist in individual creative careers?
A natural history study has provided the first comprehensive clinical description of spinal muscular atrophy (SMA) within the Amish and Mennonite communities and correlates ancestral chromosome 5 haplotypes and SMN2 copy number with disease severity. SMA is a devastating genetic disease that affects the motor neurons that control movement, eating, and breathing. The observations were conducted within a population-specific framework to elucidate subtle differences in disease expression and the subsequent impact of disease-modifying therapies administered early in life.
Interactions between radiation therapy and the immune system can improve cancer treatment. The cellular carnage caused by radiation attracts scavengers, such as dendritic cells, that present cancer cell fragments to T cells. This study suggests novel ways to improve treatment by using radiation to boost immunotherapy.
A geographic profiling tool used to catch serial criminals could help reduce the casualties of human-tiger conflict, according to scientists who collaborated on an innovative conservation research study. The results of their research, published in Nature Communications, help explain how villagers in Sumatra coexist with tigers. If used pre-emptively it could have helped cut attacks by half, saving tigers from poaching and retaliation killings.
A new report has identified an alternative method to deliver nusinersen to patients with spinal muscular atrophy (SMA) using a subcutaneous intrathecal catheter system (SIC) configured by connecting an intrathecal catheter to an implantable infusion port. SMA is a devastating genetic disease that leads to progressive degeneration of motor neurons that control movement, swallowing, and breathing. It is the leading genetic cause of infant death worldwide.