News by Subject Biology

The study, conducted in mice, is the first to show that creatine uptake is critical to the anti-tumor activities of killer T cells, the foot soldiers of the immune system.

Michigan Medicine researchers find genes that help maintain the 50-50 balance between male and female offspring in mice--and that have major implications for male infertility.

Researchers at the University of Dundee have discovered an enzyme they believe could be key to preventing Group A Streptococcus infections that cause more than 500,000 deaths worldwide each year. The enzyme works through a novel mechanism of action that can also be found in other streptococcal species, increasing the impact and relevance of this finding.

A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity.

Researchers at CHLA provide clearer picture of how lungs develop and discover novel markers to differentiate populations of lung cells implicated in lung diseases of premature babies.

In an open-source research paper, a UVA Engineering professor and her former Ph.D. student share a new, more accurate method for modeling evolutionary change.

Medical University of South Carolina researchers report in Nature Communications they have obtained 3D structural snapshots of Cdc34 in action. Cdc34 is an enzyme important for cell cycle regulation and a target for therapeutic intervention in cancer. These structures, along with studies in human cells, have revealed key features of this enzyme important for its regulation of cell growth and activity. These unique features could present opportunities for rational design of novel cancer therapeutics.

Researchers have reported for the first time producing feline induced pluripotent stem cells (fiPSCs) from adult cells of domestic cats.