Memories are stronger when the original experiences are accompanied by unpleasant odors, a team of researchers has found. The study broadens our understanding of what can drive Pavlovian responses and points to how negative experiences influence our ability to recall past events.
Neuroscientists at the RIKEN Center for Brain Science (CBS) and University College London have found an anatomical link between cognitive and perceptual symptoms in autism. Published in the Journal of Neuroscience, the study identified a posterior region of the brain whose size -- amount of gray matter -- is related to both cognitive rigidity and overly stable visual perception, two symptoms of autism that until now were only conceptually related.
University of Arizona psychologist Lee Ryan and her collaborators have proposed a precision aging model designed to help researchers better understand and treat age-related cognitive decline on an individual level.
Adults who had pediatric-onset of multiple sclerosis (MS) before they were 18 were more likely to have greater cognitive consequences than patients who developed MS as adults. This study used Swedish registry data and included 5,704 patients with MS (300 of whom had pediatric-onset of the disease), and it compared test scores reflective of information-processing efficiency.
Automated analysis of the two language variables -- more frequent use of words associated with sound and speaking with low semantic density, or vagueness -- can predict whether an at-risk person will later develop psychosis with 93 percent accuracy.
New research, published in the journal Scientific Reports, shows that women undergo a significant mental as well as physical change during the late stages of pregnancy.
A new mathematical model that predicts which choices people will make in the Iowa Gambling Task, a task used for the past 25 years to study decision-making, outperforms previously developed models. Romain Ligneul of the Champalimaud Center for the Unknown in Portugal presents this research in PLOS Computational Biology.
Apolipoproten E (apoeE) is a major genetic risk factor for the development of Alzheimer's disease, yet it tends to be understudied as a potential druggable target for the mind-robbing neurodegenerative disease. Now a research team led by the University of South Florida Health (USF Health) Morsani College of Medicine reports that a novel apoE antagonist blocks apoE interaction with N-terminal amyloid precursor protein (APP) and reduces hallmark Alzheimer's-associated pathologies.
A new preclinical study by University of South Florida neuroscientists finds that anxiety-like behavior increases when early life adversity combines with high levels of FKBP5 -- a protein capable of modifying hormonal stress response. Moreover, the researchers demonstrate this genetic-early life stress interaction amplifies anxiety by selectively altering signaling of the enzyme AKT in the dorsal hippocampus, a portion of the brain primarily responsible for cognitive functions like learning and memory.
Controlling the frequency of 'brain waves' could help to improve people's recall of memories and potentially provide a key to unlock conditions such as Alzheimer's disease, according to a new article.