A therapeutic vaccine can boost antibodies and T cells, helping them infiltrate tumors and fight off human papillomavirus (HPV)-related head and neck cancer. Researchers from the Abramson Cancer Center of the University of Pennsylvania tested the immunotherapy approach in two groups of patients with advanced head and neck squamous cell carcinoma (HNSCCa) and found 86 percent showed elevated T cell activity.
Brains of baby boys born prematurely are affected differently and more severely than premature infant girls' brains. This is according to a study published in the Springer Nature-branded journal Pediatric Research. Lead authors Amanda Benavides and Peg Nopoulos of the University of Iowa in the US used magnetic resonance imaging (MRI) scans as part of an ongoing study on premature babies to examine how the brains of baby boys and girls changed and developed.
Women that have undiagnosed sexually transmitted infections may be at greater risk of experiencing negative premenstrual symptoms (PMS), according to new Oxford University research. The study was conducted as part of a long term partnership with the female health, fertility and period-tracking app, CLUE. The findings, published in Evolution Medicine & Public Health, suggest that the presence of an undiagnosed STI might aggravate the negative premenstrual experience.
Nearly 2.3 million times last year, Americans learned they had a sexually transmitted disease. But despite these record-high infection rates for chlamydia and gonorrhea, most patients only receive treatment for their own infection -- when they probably could get antibiotics or a prescription for their partner at the same time. A team of physicians looks at the barriers that stand in the way of getting expedited partner therapy to more people.
For women, fat usually accumulates around the hips, resulting in a pear-shaped look. In men, fat tends to build up around the abdomen, creating an apple shape. As it turns out, it's healthier to be a pear than an apple. A UC Riverside research team has found that only male mice experienced neuroinflammation after being fed a high-fat diet. While females were unaffected, males showed low testosterone and reduced sperm count, in addition to neuroinflammation.
The majority of partnered, home-dwelling people in the U.S. with dementia are sexually active, according to a University of Chicago Medicine study out this week in the Journal of the American Geriatrics Society.
As the majority of studies indicate that lesbian, gay, bisexual and transgender (LGBT) self-identification generally occurs during the mid-adolescent years, the study provides unprecedented insight into early identity development.
Researchers at the University of Maryland School of Medicine (UMSOM) have made a surprising discovery: during fetal development, a particular immune cell seems to play a key role in determining the male or female characteristics of the brain.
Repeated binge drinking activates genes in an area of the brain linked to addiction differently in males and females. Genes associated with hormone signaling and immune function are affected by repeated binge drinking in female mice, whereas genes associated with nerve signaling are affected in the males. These findings have implications for alcohol abuse treatment, emphasizing the importance of considering the sex of patients when developing effective pharmaceutical therapies.
Scientists stunted the puberty of male worms by starving them before they underwent sexual maturation. In a study funded by the National Institutes of Health, the scientists suggested that stress from starvation even days before sexual maturation prevented normal changes in the wiring patterns of key neuronal circuits, which caused adult male worms to act immature.