Infertility is estimated to affect 9% of reproductive-aged couples globally, and many couples turn to assisted reproductive technology. Selecting embryos with maximum development potential plays a pivotal role in obtaining the highest rate of success. Researchers can evaluate the quality of an embryo by detecting the content of proteins secreted. In Biomicrofluidics, a method to detect trace proteins secreted by embryos using microfluidic droplets and multicolor fluorescence holds promise to select embryos for ART.
Researchers used urinary measures of biomarkers of phthalates (a group of chemicals used in plastics) and phthalate substitutes from couples undergoing fertility care and examined if higher concentrations prior to conception were associated with an increased risk of preterm birth.
Scientists have developed a precise, nanotechnology-based treatment to alleviate the pain and fertility problems associated with endometriosis, a common gynecological condition in women of childbearing age.
A study of women who experienced mental ill-health from a hormonal contraception indicates they value their mental well-being higher than a satisfactory sex life. Their experiences can influence their choice of contraception. This is one of four themes that researchers have identified in interviews with 24 women who experience negative effects of some hormonal contraception. The study, from Linköping University in Sweden, has been published in the European Journal of Contraception and Reproductive Health Care.
The factors associated with men ending treatment for erectile dysfunction have been reviewed in a study published in IJIR: Your Sexual Medicine Journal. The most influential factors reported were treatment ineffectiveness, side effects, the quality of one's intimate relationship and cost of treatment. The review also highlights the importance of men's beliefs with regards to erectile dysfunction and its treatment and suggests that these beliefs are potentially modifiable.
Women who suffer from psychiatric disorders such as depression, anxiety, mania and schizophrenia following the live birth of their first child are less likely to go on to have more children, according to the first study to investigate this in a large nationwide population. It is published in Human Reproduction.
Researchers led by Jeremy Wang of the University of Pennsylvania School of Veterinary Medicine have identified an enzyme essential for the process of male meiosis, the type of cell division that produces sperm. The protein, SKP1, controls one of the key transitions in meiosis. Understanding its role may help scientists develop new approaches to treating male infertility.
Prolonged fear and anxiety brought on by major stressors, like the coronavirus pandemic, can not only take a toll on a person's mental health, but may also have a lasting impact on a man's sperm composition that could affect his future offspring. That is the finding of a provocative new study published in the journal Nature Communications by researchers at the University of Maryland School of Medicine.
Nearly one-third of women who choose to have their ovaries removed before the natural age of menopause are susceptible to negative mood and executive dysfunction. A new study shows that a woman's risk for such disorders may be linked with the degree of childhood adversity she experienced. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).
A study published in PLOS ONE showed that an internet-based version of Harvard's Mind/Body Program for Fertility achieved results similar to the in-person program, more than doubling pregnancy rates for women experiencing infertility, compared with a control group. The findings are significant because women in infertility treatment tend not to access in-person counseling and often give up on their dream of having a child.