In vitro fertilization affects the regulatory region of genes essential for placental and embryonic growth, as well as the birth weight. A new study suggests that the effects depend on genetic variation inherited from the parents. This information could be useful in development of assisted reproduction technologies.
"Our results demonstrate, for the first time, the presence of biologically active SPGCs in testicular biopsies of chemotherapy-treated PCPBs, and their capacity to develop in vitro to different stages of spermatogenesis, including the generation of sperm-like cells," according to lead researcher Prof. Mahmoud Huleihel, a member of BGU's Shraga Segal Department of Microbiology, Immunology and Genetics. "This study may open the way for new therapeutic strategies for fertility preservation of PCPBs and for azoospermic patients."
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate that pregnancies in women with rheumatoid arthritis are associated with premature delivery and low birth weight.
The research identifies a new structure in human sperm that functions in the zygote and may provide new avenues for addressing male infertility and insights into early embryo developmental defects.
New research published in The Journal of Physiology demonstrates that adult offspring born to older mothers are more susceptible to heart risks in later life. These results could be crucial in developing preventative treatments for children born to older women.
'Mental stress is known to have an adverse effect on fertility, but there is little research on the impact of stress on sperm quality,' says Dr. Eliahu Levitas, a member of the Ben-Gurion University Faculty of Health Sciences and director of the IVF Unit at Soroka. 'This study shows that prolonged stress can have an effect on sperm quality.'
A combination of the drugs mifepristone and misoprostol can help bring closure to some women and their families suffering from miscarriage, and reduces the need for surgical intervention to complete the painful miscarriage process. Results of a new clinical trial show that while the standard drug regimen using misoprostol on its own frequently fails to complete the miscarriage, a combination of misoprostol and the drug mifepristone works much more reliably.
More than one-third of women who go to a Catholic hospital for reproductive care aren't aware they're seeking obstetrical and gynecological care at a facility that may have limited health care options due to its religious affiliation.
A case study and subsequent literature review has concluded that absent signs of clinical infection, breastfeeding should continue normally when mother and baby are diagnosed with Red Diaper Syndrome (pink-colored breast milk and pink-colored soiled diapers) caused by Serratia marcescens, an opportunistic bacteria.
Diabetes in pregnant women can have serious health consequences for both mother and baby, and the US Centers for Disease Control and Prevention has identified four target areas in which increased surveillance, screening, and preventive care can improve maternal and infant health.