A Japanese research team led by Osaka University developed a 'ratchet-like molecular machine,' which promotes uni-directional molecular motion during reactions. Inspired by dumbbell-shaped rotaxanes, their molecular machine contains two rings (stations) connected by spacers. One station has a single methyl attachment, while the other has two, like hooks. Macrocyclic α-cyclodextrin passes from the one-hooked to the two-hooked station, catalyzing deuteration of the former. Therefore, movement and reaction are coupled. This could be used in synthetic molecular motors.
When cells grow and divide to ensure a biological function, DNA must be unwound from its typical tightly packed form and copied into RNA to create proteins. When this process goes awry, the result could be diseases such as cancers. University of North Carolina School of Medicine researchers have discovered that a protein called Spt6 facilitates RNA degradation so that cells have just the right amount of RNA for the creation of proteins.
A new study finds that mTORC1 controls how 'crowded' human cells become as a person ages.
Gender and posture -- not screen time -- are biggest factors behind developing 'iPad neck' and shoulder pain, UNLV study finds.
Recent breakthroughs in nonequilibrium statistical physics have revealed opportunities to advance the 'thermodynamics of computation,' a field that could have far-reaching consequences for how we understand, and engineer, our computers.
A team of researchers at EMBL have expanded Alan Turing's seminal theory on how patterns are created in biological systems. This work, which was partly done at the Centre for Genomic Regulation (CRG), may answer whether nature's patterns are governed by Turing's mathematical model and could have applications in tissue engineering. Their results have been published on June 20 in Physical Review X.
EPFL scientists have shown that combining a brain-computer interface (BCI) with functional electrical stimulation (FES) can help stroke victims recover greater use of their paralyzed arm -- even years after the stroke.
Osaka University-led researchers discovered how oncogenic mutant cells selectively expand into surrounding normal tissues and occupy them based on prediction by computer simulation and experimental verification.
One year after researchers published their work on a physiological test for autism, a follow-up study confirms its exceptional success in assessing whether a child is on the autism spectrum.
Researchers at the Nara Institute of Science and Technology (NAIST), in partnership with scientists at the University of Tokyo, report a new miniaturized camera module that can be used to diagnose the eye. The module uses three wavelengths of near infrared light to give a clear image of the fundus that matches the performance of cameras in the clinic, but is small enough to mount on top a smartphone.