Caltech scientists discover an unexpectedly dynamic vocabulary for the language of cellular communication.
Rice University bioengineer Gang Bao and his colleagues use gene editing to correct the mutation responsible for sickle cell disease in up to 40 percent of patients' cells used for lab testing.
Collaborative research conducted in Liverpool and Oxford, published in The Red Journal, identifies the specific cellular process that helps cancer cells damaged as a result of proton beam therapy, repair themselves.
Technology that's been used to edit genomes can also spot snippets of DNA. Such detective work may enable rapid, reliable ways to identify infections and cancer.
researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University, Instituto Superior Técnico (IST, Portugal), Boston Children's Hospital, and Harvard Medical School (HMS) have published a study using an organ-on-a-chip (Organ Chip) model of the human gut that reveals the intestinal blood vessel cells may play an important part in radiation-induced intestinal injury, and it confirms that a potential radioprotective drug, dimethyloxaloylglycine (DMOG), suppresses the intestine's responses to radiation injury.
Scientists at Tokyo Institute of Technology (Tokyo Tech) have found that eukaryotic and bacterial growth regulation systems of independent origins are connected to the control of chloroplast rRNA transcription in a primitive red alga.
Digital dissection shows that two horseshoe crab appendages -- the pushing leg and the male pedipalp -- each have one more muscle than had been thought, according to a study published Feb. 14, 2018 in the open-access journal PLOS ONE by Russell Bicknell from University of New England, Australia, and colleagues.
Patients who begin care with a physical therapist for neck or back pain, rather than first seeing a physician, may realize comparable improvement in their condition at significantly reduced costs.
Published in Scientific Reports, Donald Ingber's team at the Wyss Institute leverages the organoid approach to isolate intestinal stem cells from human biopsies, but goes on to break up the organoids and culture the patient-specific cells within our Organ Chips where they spontaneously form intestinal villi oriented towards the channel lumen, and the epithelium in close apposition to human intestinal microvascular endothelium
Models for extinction risk are necessarily simple. Most reduce complex ecological systems to a linear relationship between resource density and population growth -- something that can be broadly applied to infer how much resource loss a species can survive. This week in Nature Communications, an interdisciplinary team of scientists proposes a more nuanced model for extinction that also shows why animal species tend to evolve toward larger body sizes.