Changing natural electrical signaling in non-neural cells improves innate immune response to bacterial infections and injury. Tadpoles that received therapeutics, including those used in humans for other purposes, which depolarized their cells had higher survival rates when infected with E. coli than controls. The research has applications for treatment of emerging diseases and traumatic injury in humans.
A new Tel Aviv University study finds the sedimentation of asymmetric objects in liquid is very different from that of symmetrical objects like spheres. The research may have practical applications in improving water treatment and industrial processes.
A research team from the Department of Energy's Oak Ridge National Laboratory has performed the first-ever direct nanoscale examination of a living cell membrane. In doing so, it also resolved a long-standing debate by identifying tiny groupings of lipid molecules that are likely key to the cell's functioning.
Researchers at the Wyss Institute and Spaulding Rehabilitative Hospital have discovered that patients walking in clinical robotic suits do not modify their gait in response to forces that are meant to alter the height of their steps, though they do respond to alterations in step length, providing insight into how the human brain executes walking and improving rehabilitative robot design.
Researchers have succeeded in permanently rewriting flatworms' regenerative body shape by resetting their internal bioelectric pattern memory, causing even normal-appearing flatworms to harbor the 'code' to regenerate as two-headed worms.
A team of scientists have traced the evolution of whale size through more than 30 million years of history and found that very large whales appeared along several branches of the family tree about 2 to 3 million years ago. Increasing ice sheets in the Northern Hemisphere during this period likely altered the way whales' food was distributed in the oceans and enhanced the benefits of a large body size, the scientists say.
The first total synthesis of dimeric securinega alkaloid (-)-flueggenine C was completed via an accelerated intermolecular Rauhut-Currier (RC) reaction. The research team led by Professor Sunkyu Han in the Department of Chemistry succeeded in synthesizing the natural product by reinventing the conventional RC reaction.
By some estimates, more than 1 million people contract infections from medical devices in US hospitals each year, many of which are due to biofilms. A new study suggests a possible new way to prevent such biofilms from forming, which would sharply reduce incidents of related hospital-borne infection.
Siberian biophysicists have conducted a research concerning a biological effect of low-dose gamma radiation. The results have been published in the Journal of Environmental Radioactivity, one of the leading scientific journals in the world among those dedicated to the issues of environmental radioactivity.
Biophysicists have proposed a universal mechanism for the 'sense of smell' in bacteria. This was done by obtaining the structure of the NarQ protein from Escherichia coli (E. coli). The paper published in Science will help us understand how bacteria 'communicate' with one another and form biofilms on sterile surfaces or inside the human body. Drugs which affect bacteria's 'sense of smell' could potentially be used as substitutes for modern antibiotics.