Indicators of despair -- depression, suicidal ideation, drug use and alcohol abuse -- are rising among Americans in their late 30s and early 40s across most demographic groups, according to new Vanderbilt University research. These findings suggest that the increase in 'deaths of despair' observed among low-educated middle-aged white Baby Boomers in recent studies may begin to impact the youngest members of Generation X more broadly in the years to come.
A Japan-based research team led by Kanazawa University has revealed neuronal mechanisms underlying the formation and retrieval of cocaine use-associated memories. Their research sheds light on how drug addiction develops and reveals pathways that can be exploited for the development of strategies to treat cocaine addiction.
Researchers in Colorado examined medical records of 250 patients who received endoscopic procedures after 2012, when the state legalized recreational cannabis. They found patients who smoked or ingested cannabis on a daily or weekly basis required 14% more fentanyl, 20% more midazolam, and 220% more propofol to achieve optimum sedation for routine procedures, including colonoscopy.
The opioid epidemic may have cost U.S. state and federal governments up to $37.8 billion in lost tax revenue due to opioid-related employment loss, according to Penn State researchers.
Nurse practitioners and nursing students can use local, real-time maps of opioid overdoses to inform their clinical work with adolescents in community health settings, finds new research from NYU Rory Meyers College of Nursing.
When it comes to addressing the national opioid crisis, most of the research has focused on the physical health risks faced by people with opioid use disorder, such as overdose and infectious disease. For the first time, a University of Massachusetts Amherst public health scientist studied the impact of treating opioid use disorder on the risk for arrest and incarceration, comparing the effects of two different medications approved for the condition.
Stepping up efforts to prevent transmission of hepatitis C among people who inject drugs, could reduce future infections by 43% globally, according to a study by researchers at the University of Bristol published in the Lancet Gastroenterology and Hepatology today.
Researchers from the Institute of Neuroscience and their collaborators revealed a new cellular mechanism for amyotrophic lateral sclerosis (ALS), suggested a novel therapeutic strategy targeting the RNA degradation pathway, and identified an asthma drug as a potential medication for ALS.
Researchers report combining cannabinoids with morphine did not significantly increase impulsivity or memory impairment in a study conducted in rhesus monkeys. The findings suggest using opioids and marijuana together could offer a safe way to cut opioid dosage among patients suffering from pain and thereby reduce their risk of becoming addicted to opioids.
With a growing number of states legalizing recreational or medical marijuana, more women are using the drug during pregnancy, in part due to its reported ability to relieve morning sickness. A new study, conducted in rats, sheds light on how cannabis exposure affects the brain of a developing fetus.