In a randomized, placebo-controlled study, researchers from Israel have shown that cannabis can produce clinical remission in up to 65 percent of individuals after eight weeks of treatment, but that this improvement does not appear to result from a dampening down of the underlying inflammatory process.
A Brown University study found that many young adults who tried fentanyl test strips reduced overdose risk by using less, going slower or using with someone else present.
Adolescent THC exposure reduces the branching of prefrontal cortical neurons and the number of spines, which are critical for cellular communication. This adolescent exposure is also associated with a reorganization of the gene expression of specific genes that are predominantly related to neuron development, synaptic plasticity and chromatin organization (epigenetic mechanisms).
In a survey-based study of 9,449 university students at a large, public Midwestern university, misusers of prescription opioid medications were more likely to live off campus, have a lower grade point average, and exhibit increased impulsivity.
Doping remains an ongoing problem in competitive sports, but researchers have never before asked athletes to rank the effectiveness of available anti-doping strategies. A new poll of a national pool of top German cyclists and field athletes finds that, according to the athletes, better diagnostics, increased bans and laws against doping are perceived as far more effective than increased fines or leniency programs.
Use of tobacco & marijuana products frequently featured in hip-hop music videos.
A high-fat diet in female mice affects their offspring's obesity, insulin resistance and addictive-like behaviors for three generations, according to a study published in the open-access journal Translational Psychiatry.
A team of researchers at the Icahn School of Medicine at Mount Sinai and the University of Washington has designed a modeling system that integrates genomic and temporal information to infer causal relationships between genes, drugs, and their environment, allowing for a more accurate prediction of their interactions over time.
Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually develop drug resistance, leaving doctors desperate for alternatives. Now, researchers from Case Western Reserve University School of Medicine have uncovered a previously uncharacterized, bridge-like structure within the human estrogen receptor that could serve as a valuable new drug target.
A revolutionary drug test can detect amphetamines, cannabis, cocaine and opiates from the sweat of single fingerprint sample in just 10 minutes. The research shows that the technology works on both the living and deceased.