For anyone who has accidentally injured themselves, Dr. Zachary Campbell not only sympathizes, he's developing new ways to blunt pain. Campbell, who researches pain on the molecular level at the University of Texas at Dallas, recently published a study in the journal Nature Communications that describes a new method of reducing pain-associated behaviors with RNA-based medicine, creating a new class of decoy molecules that prevent the onset of pain.
Young people with cannabis dependence have altered brain function that may be the source of emotional disturbances and increased psychosis risk that are associated with cannabis abuse, according to a new study published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. The alterations were most pronounced in people who started using cannabis at a young age. Findings reveal potential negative long-term effects of heavy cannabis use on brain function and behavior.
The new ORION e-health psychoeducational tool, designed to help opioid-dependent individuals prevent an overdose, can impart new knowledge and impact a person's intention to change opioid abuse behavior, but it did not improve overall self-efficacy in overdose prevention.
Results of a national study led by public health scientist Elizabeth Evans at the University of Massachusetts Amherst, with others at the US Department of Veterans Affairs (VA) and the University of California, Los Angeles, suggest that risk for alcohol and drug use disorders among United States military veterans is increased by childhood adversity, and in ways that are different between women and men and different compared to the civilian population.
Alcohol, marijuana, and ecstasy each have very different sexual effects, from attraction and desire to sensitivity to sexual dysfunction, finds a study by the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU Meyers College of Nursing.
Efforts to reverse the nation's opioid epidemic remain beset by the stigma associated with drug use, a group of OHSU researchers write in a year-end review. The researchers emphasize the need for the American health care system to embrace medications such as methadone to treat opioid use disorder, provide addiction treatment in primary care clinics and develop non-addictive alternatives for chronic pain.
ETH chemists have synthesized several variants of THC, the active ingredient in cannabis. Its structure can be altered with light, and the researchers have used this to create a new tool that can be used to more effectively study the body's own cannabinoid system.
Innovations in primary care: Behavioral approach to treating Opioid use disorder.
A strategy to test the general population for hepatitis B and C viruses in areas of high prevalence had high test uptake but did not detect hidden chronic hepatitis C infections.
Patients with musculoskeletal conditions who receive prescription opioids are more satisfied with their care than comparable patients who do not receive opioids.