Common antidepressants interact with the opioid pain medication tramadol to make it less effective for pain relief, according to a study published in the journal Pharmacotherapy. These findings have important implications for the opioid epidemic, suggesting that some patients suspected of drug-seeking may in fact be under-medicated and just are seeking more effective pain relief. They also could help explain why some people exceed the prescribed dose of tramadol, increasing their risk of addiction.
A small study looked at whether reducing the number of opioid tablets prescribed after knee surgery would reduce postoperative use and if preoperative opioid-use education would reduce it even more. The study included 264 patients who underwent anterior cruciate ligament (ACL) surgery at a single academic ambulatory surgery center.
Having a family member who was previously dispensed prescription opioids was associated with higher odds of overdose for individuals who themselves didn't have an opioid prescription in this analysis of insurance company data. The study included 2,303 people with the earliest date of an opioid overdose in a family and 9,212 others in the insurance database for comparison.
Young gay and bisexual men are frequent users of alkyl nitrites, or poppers, but few show signs of addiction, risky consumption habits or other psychosocial problems, a study shows.
A new article published by researchers from University of Puget Sound and University of Washington reports that, based on analysis of public wastewater samples in at least one Western Washington population center, cannabis use both increased and substantially shifted from the illicit market since retail sales began in 2014.
A detailed analysis of recent national data on suicide rates among young people ages 15 to 24 reports 6,241 suicides in 2017, and suicide rates at ages 15 to 19 and 20 to 24 that have increased to their highest point since 2000. This study used data from the Centers for Disease Control and Prevention to take a closer look at suicide rates in the United States among young people and to see if increases from 2000 to 2016 were continuing.
Medical marijuana is legal in some form in 33 states, but relatively little is known about the availability of marijuana and use among younger people. A new study finds that younger adults who live in neighborhoods with more medical marijuana dispensaries use marijuana more frequently than their peers and have more-positive views about the drug. The associations were strongest among young adults who lived near dispensaries that had storefront signs.
The use of cartoon characters in ads for e-cigarettes and e-liquids may be attracting young people to use the products in the future, according to a new USC study.
Cardiac MRI has a pivotal role to play in the diagnosis of cocaine-induced cardiovascular diseases, according to a new article.
Overdoses and suicides were among the most common reasons for mothers dying within a year of giving birth in California, according to a new study from Michigan State University and the University of California, Merced.