People with a family history of alcohol use disorder (AUD) release more dopamine in the brain's main reward center in response to the expectation of alcohol than people diagnosed with the disorder, or healthy people without any family history of AUD, reports a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.
About 22 million Americans are substance dependent, yet only 2.5 million seek treatment. Reviewing 5,443 records of adult substance use treatment clients, a new study examined treatment readiness, or the characteristics that are likely to promote treatment engagement, to predict who seeks and stays in treatment. Results show that white and black race, being male, lower levels of education, and being married or divorced (vs. never married) were all negatively related to substance-use treatment engagement.
New research published in Addiction, conducted by researchers from the universities of Liverpool and Sheffield, highlights the potential benefits of reducing the standard serving size of alcoholic beverages.
A new discovery shows that opioids used to treat pain, such as morphine and oxycodone, produce their effects by binding to receptors inside neurons, contrary to conventional wisdom that they acted only on the same surface receptors as endogenous opioids, which are produced naturally in the brain.
A new review published online today in the journal Addiction has compiled the best, most up-to-date source of information on alcohol, tobacco, and illicit drug use and the burden of death and disease. It shows that in 2015 alcohol and tobacco use between them cost the human population more than a quarter of a billion disability-adjusted life years, with illicit drugs costing a further tens of millions.
Scientists at The University of Texas at Austin have successfully tested in animals a drug that, they say, may one day help block the withdrawal symptoms and cravings that incessantly coax people with alcoholism to drink.
Maintaining five healthy habits -- eating a healthy diet, exercising regularly, keeping a healthy body weight, not drinking too much alcohol, and not smoking -- during adulthood may add more than a decade to life expectancy, according to a new study led by Harvard T.H. Chan School of Public Health.
A study by the University of Washington finds that a community-based approach to substance-abuse prevention, which can include after-school activities, can affect young people into adulthood.
Wines and beers labelled as lower in alcohol strength may increase the total amount of alcoholic drink consumed, according to a study published in the journal Health Psychology. The study was carried out by the Behaviour and Health Research Unit at the University of Cambridge in collaboration with the Centre for Addictive Behaviours Research at London South Bank University.
A new study is the first to show that binge drinking by expectant mothers can impair the mental health of their offspring. Italian researchers report that rat mothers who drank in a binge-like manner during pregnancy and lactation were more prone to depressive behaviors -- and so were their offspring. Moreover, alcohol-triggered heritable changes in the mother made their offspring more vulnerable to mood disturbances and alcohol abuse as adolescents.