Common antidepressants interact with the opioid pain medication tramadol to make it less effective for pain relief, according to a study published in the journal Pharmacotherapy. These findings have important implications for the opioid epidemic, suggesting that some patients suspected of drug-seeking may in fact be under-medicated and just are seeking more effective pain relief. They also could help explain why some people exceed the prescribed dose of tramadol, increasing their risk of addiction.
A new study provides evidence to support a simple measurement for diagnosing clinically significant airflow obstruction, the key characteristic of chronic obstructive pulmonary disease (COPD), the fourth leading cause of death in the United States. The study found that a 70% ratio of two indicators of lung function proved as or more accurate than other thresholds for predicting COPD-related hospitalizations and deaths.
New research discovers employees who view pornography aren't just costing companies millions of dollars in wasted time, they're causing harm to the company.
A prevailing theory in neuroscience holds that people make decisions based on integrated global calculations that occur within the frontal cortex of the brain. However, Yale researchers have found that three distinct circuits connecting to different brain regions are involved in making good decisions, bad ones and determining which of those past choices to store in memory, they report June 25 in the journal Neuron.
The adverse effect of maternal smoking during pregnancy is well established and associated with several negative neonatal outcomes (such as low birth weight and preterm birth). It is also evident in some studies that the semen quality of men exposed to prenatal maternal smoking is generally more impaired than that of unexposed men. However, there is little known about the effect of paternal smoking in the time leading up to and during pregnancy.
A small study looked at whether reducing the number of opioid tablets prescribed after knee surgery would reduce postoperative use and if preoperative opioid-use education would reduce it even more. The study included 264 patients who underwent anterior cruciate ligament (ACL) surgery at a single academic ambulatory surgery center.
'Our findings suggest that certain types of stores -- tobacco shops, convenience stores and those with a lot of tobacco advertising -- are more likely to sell tobacco to a young person without checking his or her ID.'
Having a family member who was previously dispensed prescription opioids was associated with higher odds of overdose for individuals who themselves didn't have an opioid prescription in this analysis of insurance company data. The study included 2,303 people with the earliest date of an opioid overdose in a family and 9,212 others in the insurance database for comparison.
Smoking increases both men's and women's risk of a major heart attack at all ages, but women smokers have a significantly higher increased risk compared to men, especially women under 50 years old, according to a study in the Journal of the American College of Cardiology. Despite the increased risk, smokers can reduce their risk to that of a never smoker in as little as a month after quitting.
Chronic diseases, such as stroke, ischemic heart disease, and lung cancer, now represent the leading causes of premature death in China, according to a new scientific study. The rise in non-communicable diseases reflects declines in maternal and child mortality over nearly three decades, largely the result of economic growth and increasing levels of education. In addition, China has instituted national programs targeting infectious diseases.