A collaboration between Babraham Institute scientists and AstraZeneca provides new insights into the role of PTEN, a major cancer gene, in controlling cell growth and behaviour. PTEN is the second most commonly altered gene in human cancers, particularly prostate cancers, and this work could help to develop and target new treatments.
Freiburg scientists explain assembly and transport function of 'old' calcium pumps by 'new' partner proteins.
A metallic probe invented at Rice University that lights up when it binds to a misfolded amyloid beta peptide has identified a binding site that could facilitate better drugs to treat Alzheimer's disease. When the probe is illuminated, it catalyzes oxidation of the protein in a way that might keep it from aggregating in the brains of patients.
Two UA materials science and engineering researchers have experimentally verified the electrochemical processes that control charge transfer rate from an organic polymer to a biomarker molecule. Their findings, reported in Nature Communications, may enhance selectivity for biomarkers in bioelectronic devices.
Using a revolutionary live-cell microscopy technique, an international team of scientist has observed for the first time individual receptors for hormones and widely used drugs at work in intact cells.
Science has long inspired the arts, but examples of the reverse scenario are sparse. Now scientists who set out to produce a 'Star Wars' parody have inadvertently created such an example. Incorporating animation techniques from the film industry, the researchers developed a robust new modeling tool that could help spur new molecular discoveries. Their project, reported in ACS Nano, resulted in a short film about fertilization called 'The Beginning.' For a look behind-the-scenes, watch ACS' Headline Science video.
A new Tel Aviv University study reveals that it is possible to repurpose the function of different mature cells across the body and harvest new tissue and organs from these cells.
New study finds 'messy' microscopic structures on petals of some flowers manipulate light to produce a blue colour effect that is easily seen by bee pollinators. Researchers say these petal grooves evolved independently multiple times across flowering plants, but produce the same result: a floral halo of blue-to-ultraviolet light.
Loading nanofiber sutures with vitamin D induces the production of an infection-fighting peptide, new research shows.
Every year, millions of tonnes of plastic debris ends up in the sea. The path taken by plastic to reach the sea must be elucidated before it will be possible to reduce the volume of plastic input. To date, there was only little information available on this. It has now been followed up by an interdisciplinary research team who were able to show that plastic debris is primarily carried into the sea by large rivers.