Small infections can be fatal: Millions of people die each year from sepsis, an overreaction of the immune system. A new immune signaling molecule, designed by a research team from the Technical University of Munich (TUM), now provides the basis for potential new approaches in sepsis therapy.
Some people use fidget spinners -- flat, multi-lobed toys with a ball bearing at the center -- to diffuse nervous energy or whirl away stress. Now, researchers have found a surprising use for the toys: separating blood plasma for diagnostic tests. The new approach, reported in ACS' journal Analytical Chemistry, could be useful for medical applications in regions of the world that lack electricity and other resources.
An international collaboration including Osaka University researchers has found that a peptide hormone regulates two different cell division processes that generate centrally important structures for the flow of water through plants. By binding to different receptors, the hormone controls the formation of not only xylem (the vessels that transport water up from the roots), but also stomata (the leaf pores through which water evaporates).
Plants don't need noses to smell. The ability is in their genes. Researchers at the University of Tokyo have discovered the first steps of how information from odor molecules changes gene expression in plants. Manipulating plants' odor detection systems may lead to new ways of influencing plant behavior.
Scientists at USC Michelson Center and Japan's Nagoya University find and test a promising drug that stops cancer by interfering with the cancer cells' metabolism and other circadian-related functions.
A new collection of reviews and original research articles illustrate how new technologies and advanced cell culture are accelerating basic research, drug discovery and drug development.
Climate change causes an increase in the number of freshwaters that run dry, at least temporarily. Around 90,000 square kilometres of water surface have already vanished in the last 30 years. This trend is not only a threat to drinking water reserves and major ecosystems - dried freshwaters also play an important role in the global carbon cycle. Two recently published studies reveal that the importance of this phenomenon has so far been underrated.
A KAIST team presents a noninvasive light-sensitive photoactivatable recombinase suitable for genetic manipulation in vivo. The highly light-sensitive property of photoactivatable Flp recombinase will be ideal for controlling genetic manipulation in deep mouse brain regions by illumination with a noninvasive light-emitting diode. This easy-to-use optogenetic module made by Professor Won Do Heo and his team will provide a side-effect free and expandable genetic manipulation tool for neuroscience research.
Heart disease is the greatest killer in the world today. A new study in sheep, publishing Jan. 22 in the open-access journal PLOS Biology, by a team from Cambridge University, finds that offspring whose mothers had a complicated pregnancy may be at greater risk of heart disease in later life, suggesting that our cards may be marked even before we are born.
What happens to sex pheromones as new species emerge? New research publishing Jan. 22 in the open-access journal PLOS Biology studies sex pheromones in the fission yeast Schizosaccharomyces pombe, revealing an 'asymmetric' pheromone recognition system in which one pheromone operates extremely stringently whereas the other pheromone is free to undergo a certain degree of diversification, perhaps leading to a first step towards speciation.