A Freiburg molecular medicine specialist's team discovers a new disease mechanism in the mitochondria.
Cell division is the basis of all life. Even the smallest errors in this complex process can lead to grave diseases like cancer. Certain proteins have to be switched on or off at certain times for everything to go according to plan. Biophysicists and medical biochemists at Martin Luther University Halle-Wittenberg (MLU) have managed to describe the underlying mechanism of this process.
Soil salinity poses a major threat to food security, greatly reducing the yield of agricultural crops. Rising global temperatures are expected to accelerate the buildup of salt in soil, placing an increasing burden on agricultural production. In a new study published in The Plant Cell, a team of researchers identified a gene that limits yield losses in rice plants exposed to salt stress and deciphered the underlying mechanism.
Researchers have used a combination of light and genetic engineering to controlling the metabolism, or basic chemical process, of a living cell. Building on techniques that already have transformed the field of neuroscience, the researchers used light to control genetically-modified yeast and increase its output of commercially valuable chemicals.
Not only it inhibits enzymes essential to Plasmodium's survival in two key stages of its lifecycle in humans, but triclosan also performed well in tests against resistant parasites, an international study reveals. The efficiency of malaria treatment with mostly used drugs is undermined by resistant lineages and by the fact that patients present severe side effects in 10 percent of the cases.
Stephen Arnold and his team at NYU Tandon's MicroParticle PhotoPhysics Laboratory for BioPhotonics are the first to find a way to determine the density of charges on an area of a whisperinig gallery mode micro-bead's surface, as well as the charge of an ensnared nanoparticle or virus, which could allow researchers and manufacturers not just to identify nanoparticles, but to manipulate them.
Researchers from the University of Dundee and the Francis Crick Institute have made a significant discovery about a cellular pathway associated with developmental defects and a myriad of diseases ranging from alopecia to colorectal cancer. The research, jointly led by Dundee's Dr. Gopal Sapkota and Professor Sir Jim Smith of the Crick, examined the role of a protein called PAWS1 in the Wnt signalling pathway, which is of fundamental importance in shaping developing embryos and controlling cell fate in adults.
Scientists from Moscow State University (MSU) working in an international team of researchers identified the structure of one of the key regions of telomerase -- a cell immortality enzyme. Structural and functional studies on this protein are important for the development of potential anticancer drugs. The results of the study have been published in the highly-rated Nucleic Acids Research journal.
Cows burp up more gas than you might think possible when they're digesting grass. Most of that gas is methane, a potent greenhouse gas, which is bad news for the planet. This video from Reactions explains why the chemistry of cow guts is such a busy area of study.
Researchers of the University of Helsinki, Finland, developed an integrated workflow for interaction proteomics, which -- as they describe it -- proves almost as versatile as the Swiss Army Knife.