In this study of 72,000 adolescents and young adults, higher risk of youth overdose was associated with exposure to family members with opioid prescriptions and young people's own opioid prescriptions.
A species of a lipid that naturally helps skin injuries heal appears to also aid repair of common corneal injuries, even when other conditions, like diabetes, make healing difficult, scientists report.
An experimental model of severe Duchenne muscular dystrophy that experiences a large spike in TGFβ activity after muscle injury shows that high TGFβ activity suppresses muscle regeneration and promotes fibroadipogenic progenitors, Children's National Hospital researchers find.
In an analysis of 2019 mass shootings and hospital locations, researchers at Children's Hospital of Philadelphia (CHOP) found that the closest hospital to more than 70% of mass shootings was a non-trauma center, where sudden, high casualty loads were more likely to overwhelm capacity and trauma-specific care options may have been limited. They also found that in more than half of mass shooting events, the nearest pediatric trauma center was more than 10 miles away.
Nontrauma center hospitals were the nearest hospitals to most of the mass shootings (five or more people injured or killed by a gun) that happened in the US in 2019. This study examined distances to trauma centers and nontrauma center hospitals for 187 mass shootings.
Senior citizens who are not vitamin D deficient have a better chance of walking after hip fracture surgery, according to a Rutgers-led study. The findings in The American Journal of Clinical Nutrition suggest that vitamin D deficiency could limit mobility in older adults, said senior author Sue Shapses, a professor in the Department of Nutritional Sciences at the School of Environmental and Biological Sciences at Rutgers University-New Brunswick.
A group of researchers from Charité - Universitätsmedizin Berlin has discovered a new mechanism of long-lasting pain relief. The cell-signaling protein interleukin-4 induces a specific type of blood cell to produce endogenous opioids at the site of inflammation. The researchers' findings have been published in the Journal of Clinical Investigation (JCI) Insight*.
Data from Sweden were used to compare 115,933 pairs of children who did or didn't use proton pump inhibitors (PPIs) to examine the association between PPI use and risk of fracture in children.
A new study in the American Journal of Preventive Medicine, published by Elsevier, found that motor vehicle crashes involving drivers with blood alcohol concentrations (BACs) below the legal limit of 0.08 percent accounted for 15% of alcohol-involved crash deaths in the United States. Of these deaths, 55% of fatalities were individuals other than the drinking driver, and these crashes were more likely to result in youth fatalities compared with crashes above the legal BAC limit.
Using a mouse model, a pair of UC Riverside researchers demonstrated the formation of fear memory involves the strengthening of neural pathways between two brain areas: the hippocampus, which responds to a particular context and encodes it, and the amygdala, which triggers defensive behavior, including fear responses.