Commercial approaches to ultrasensitive protein detection are starting to become available, but they are based on expensive optics and fluid handlers, which make them relatively bulky and expensive. Knowing that having this sort of diagnostic system available as a point-of-care device would be critical for many conditions, especially traumatic brain injury, Penn engineers have developed a test that uses off-the-shelf components and can detect single proteins with results in a matter of minutes.
Children's research-clinicians created a novel preclinical model that mimics the persistent interneuron loss seen in preterm human infants, identifying interneuron subtypes that could become future therapeutic targets to prevent or lessen neurodevelopmental risks.
Scientists from the National University of Science and Technology MISIS developed a unique hybrid bone implant, the core of which is made of porous ultra high molecular weight polyethylene, and the shell is made of polyetheretherketone. Thanks to the combination of the unique properties of the two polymers, it was possible to create an implant that imitates the bone structure and is additionally reinforced to increase strength and elasticity.
Driving while on prescription opioids plays an increasingly significant role in fatal motor vehicle crashes, irrespective of alcohol use and demographic characteristics, according to a new study at Columbia University Mailman School of Public Health. The prevalence of prescription opioids detected for the years studied increased from 2 percent to 7 percent among crash initiators and from .9 percent to 4.6 percent among non-initiators.
Sierra Leone has few doctors and even fewer surgeons to serve its seven million people. Since 2011, a non-profit group called CapaCare has been training community health officers to perform basic lifesaving surgeries. A new study shows the programme is working well when it comes to the most common surgery in the country -- Caesarean sections.
Daniela Kaufer, a professor at UC Berkeley and fellow in the CIFAR Child & Brain Development program, has discovered one of the biological pathways that lead to age-related cognitive decline, and has found clues on how to reverse the aging process in the brain.
Indiana University School of Medicine researchers have developed a test that objectively measures pain biomarkers in blood. The test could help physicians better treat patients with precision medicine, and help stem the tide of the opioid crisis.
In a randomized, controlled pilot trial published Feb. 13, 2019, in PLOS ONE, UC San Diego School of Medicine researchers found that participants pre-treated with noninvasive vagus nerve stimulation experienced less pain after heat stimulus than mock-treated participants.
What do heart disease, stroke, sepsis, and cancer have in common, aside from being deadly diseases? They're all linked to platelets, the cells in our blood that normally help our blood clot. New research from the Wyss Institute has created 'decoy' platelets that can both prevent blood clots and keep cancer from spreading.
UCLA researchers have found that people involved in electric scooter accidents are sometimes injured badly enough -- from fractures, dislocated joints and head injuries -- to require treatment in an emergency department.