A stem cell biologist from City University of Hong Kong (CityU), together with his collaborators, has developed a novel strategy, called in vivo priming, to 'train' the stem cells to stay strong after implantation to the damaged heart via the 3D-printed bandage-like patch. The positive results of the study show that an in vivo priming strategy can be an effective means to enhance cardiac repair.
A new study from the University of Birmingham has shown that fecal microbiota rransplants (FMT) are highly successful in treating patients with Clostridioides difficile (C. diff) infection.
Inspired by a tactic cancer cells use to evade the immune system, University of Pittsburgh researchers have engineered tiny particles that can trick the body into accepting transplanted tissue as its own. Rats that were treated with these cell-sized microparticles developed permanent immune tolerance to grafts -- including a whole limb -- from a donor rat, while keeping the rest of their immune system intact, according to a paper published today in Science Advances.
A new method of bioprinting uses aspiration of tiny biologics such as spheroids, cells and tissue strands, to precisely place them in 3D patterns either on scaffolding or without to create artificial tissues with natural properties, according to Penn State researchers.
Myocardial blood flow (MBF) and myocardial flow reserve (MFR) have been identified as accurate indicators for graft failure after cardiac transplantation, according to research published in The Journal of Nuclear Medicine.
In the past two decades, death rates after liver transplantation have dropped by more than half in the UK, according to a recent analysis of almost 10,000 liver transplant recipients published in BJS (British Journal of Surgery).
So far, kidney transplantation has generally not been offered to elderly patients (>75 years) because of the perioperative risks. Nor has it been clearly established whether transplanted patients in this age benefit significantly. In a new study published in NDT, the graft survival proved to be excellent, and nearly all patients remained dialysis-free. Is it time to rethink established common practice?
A new website developed by researchers at Hennepin Healthcare Research Institute (HHRI) and the University of Minnesota (UMN) is making it easier for organ transplant candidates to choose which transplant center is right for them. The website, transplantcentersearch.org, was developed for candidates seeking kidney, liver, heart and lung transplants. Data for liver centers is currently live. Data for other organs will soon be available.
Kidney patients benefit by accepting kidneys from donors with hepatitis C, according to a University of Cincinnati physician-researcher. Making the choice reduces organ wait time for kidney patients while saving money over the long run. It also improves the quality of life and life expectancy for kidney patients.
The Swedish team responsible for uterine transplantation research has, for the first time, transplanted a uterus from a deceased donor. The operation proceeded without complications and the recipient is doing well.