A team of scientists from the University of Colorado School of Medicine and the Charles C. Gates Center for Regenerative Medicine at CU Anschutz has reported a more efficient approach to reprogramming a patient's diseased skin cells into stem cells, raising hopes for future clinical trials and potential cures for critical illnesses.
Children with chronic kidney disease (CKD) have lower IQs and poorer educational outcomes than healthy children a new review of evidence led by University of Sydney scholars reveals.
A bone marrow transplant is often the only therapy available to save leukaemia patients, but the risk of complications is high. Nearly half of all patients experience an unwanted reaction of their immune system, which often attacks their skin and liver and in up to 50 percent of cases the intestines. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have succeeded in deciphering what causes this in some instances life-threatening inflammation of the intestines.
Results from a retrospective study presented at the 2018 BMT Tandem Meetings dispute age as a limiting factor to transplant eligibility, showing no differences in 4-year outcomes for patients older or younger than age 65.
A group of NUST MISIS's young scientists, for the very first time in Russia, has presented a new therapeutic material based on nanofibers made of polycaprolactone modified with a thin-film antibacterial composition and plasma components of human blood. Biodegradable bandages made from these fibers will accelerate the growth of tissue cells twice as quickly, contributing to the normal regeneration of damaged tissues, as well as preventing the formation of scars in cases of severe burns.
In a paper in Cell Host & Microbe, scientists provide a statistical model predicting which bacterial strains will engraft after a fecal transplant. It is the first predictive strategy for developing a synthetic probiotic. The researchers also found that recipients acquired new bacteria that were previously undetected in both the donor and the recipient, suggesting that the post-fecal transplant microbiome is a mixture of bacterial strains from the donor, recipient, and the environment.
Future Science Group (FSG) today announced the publication of an article in Future Science OA demonstrating the first use of multispectral imaging in gynecology, in a uterine transplant setting.
In a new Johns Hopkins study of patient and graft survival trends for pediatric liver transplant recipients between 2002 and 2015, researchers found that outcomes for alternatives to whole liver transplantation (WLT), such as splitting a liver for two recipients or using a part of a liver from a living donor, have improved significantly.
A research team from Tongji University in China have made a breakthrough in human lung regeneration technology. For the first time, researchers have regenerated patients' damaged lungs using autologous lung stem cell transplantation in a pilot clinical trial. The study can be found in the open-access journal Protein & Cell which is published by Springer Nature.
Before medical science can bioengineer human organs in a lab for therapeutic use, two remaining hurdles are ensuring genetic stability -- so the organs are free from the risk of tumor growth -- and producing organ tissues of sufficient volume and size for viable transplant into people. Scientists report in Stem Cell Reports achieving both goals with a new production method for bioengineered human gut and liver tissues.