Some of America's favorite Independence Day fireworks emit lead, copper, and other toxins, a new study suggests. These metals, which are used to give fireworks their vibrant color, also damage human cells and animal lungs.
In a pair of new studies, Rolf Halden, director of the ASU Biodesign Center for Environmental Health Engineering and author for the 2020 Book Environment, describes the process and highlights important new findings extracted from the municipal wastewater most of us contribute to on a daily basis. Halden is also a professor at ASU's School of Sustainable Engineering and the Built Environment.
All per- and polyfluorinated substances (PFAS) should be treated as one class and avoided for nonessential uses, according to a peer-reviewed article published today in Environmental Science & Technology Letters.
Researchers led by Natàlia Carulla find that specific amyloid-beta (Aβ) protein ensembles have the capacity to disrupt the membrane of neurons, causing their death. The results have been published in the journal Nature communications.
Bacterial toxins causing different illnesses share similar molecular mechanisms in a finding that could help treatment development as well as explain the emergence of new diseases.
Fresh insights into why some harmful substances are so efficient at causing cancer could aid the quest for better treatments. New research reveals how chemicals can cause changes in cells to help them dodge the body's immune system and build resistance to cancer drugs. Scientists tracked the impact of a toxic substance - similar to compounds found in tobacco, exhaust and some plants - to better understand how chemicals cause mutations in our cells' DNA.
Scientists have found that man-made mercury pollution has reached the bottom of the deepest part of the ocean -- the Marianas Trench. This has significant implications for how mercury affects the marine environment, and how it may be concentrated in the food chain. The findings, which come from two independent research groups, are presented at the Goldschmidt geochemistry conference.
These exist complex challenges when developing Live Biotherapeutic Products (LBPs). The safety assessment poses challenges because of the potential sensitivity of the target population, the 'live' nature and the complicated mode of action of LBPs. This article proposes a risk assessment roadmap for LBPs and appropriate solutions for non-clinical programmes and First-in-Human clinical safety trials. The approach is largely supported by academic and industry representatives and will support future LBP safety assessment studies in Europe/US.
Scientists develop AI-based tool to predict adverse drug events. Such events are responsible for some 2 million U.S. hospitalizations per year. The free, open-source system could enable safer drug design, optimize drug safety
A new study appearing in the journal CHEST®, published by Elsevier, documents an increased incidence of silicosis, which progressed rapidly to massive pulmonary fibrosis in a significant proportion of patients who had previously worked artificial stone (AS), also called artificial quartz agglomerate or conglomerate, a popular new countertop material, despite cessation of exposure after diagnosis.