Researchers from SMART have developed a method to produce engineered lysins that can be used to selectively kill bacteria of interest while leaving others unharmed. The discovery presents a promising alternative to antibiotics for treating existing drug-resistant bacteria without the risk of causing resistance.
An inexpensive, FDA-approved drug -- cholestyramine -- taken in conjunction with an antibiotic prevents the antibiotic from driving antimicrobial resistance, according to new research by scientists at Penn State and the University of Michigan.
To develop effective therapeutics against pathogens, scientists need to first uncover how they attack host cells. An efficient way to conduct these investigations on an extensive scale is through high-speed screening tests called assays.
UC San Diego researchers discovered that the makeup of a person's gut microbiome is linked to their levels of active vitamin D, and revealed a new understanding of vitamin D and how it's typically measured.
In recent decades, researchers have found that most mammals' guts are surprisingly complex environments - home to a variety of microbial ecosystems that can profoundly affect an animal's well-being. Scientists have now learned that the bear appears to be an exception, with its gut playing host to a microbial population that varies little across the intestinal tract.
A seven-year analysis of almost 10,000 Harmful Algal Blooms (HAB) events worldwide over three decades will be published by the HAB Programme of UNESCO's Intergovernmental Oceanographic Commission. More than 100 scientists in 112 countries contributed to the synthesis and analysis of HAB data gathered from 1985 to 2018 -- a first-ever big data approach to detecting changes in the costly phenomenon's global distribution, frequency, and intensity.
An international collaboration between researchers at the Niels Bohr Institute, University of Copenhagen, Oxford University, and University of Sheffield has revealed that colonies of slow moving bacteria can expand significantly quicker than their fast moving counterparts - and how. The result is now published in Nature Physics.
Antibiotics have revolutionized medicine by providing effective treatments for infectious diseases such as cholera. But the pathogens that cause disease are increasingly developing resistance to the antibiotics that are most commonly used. Scientists at the Friedrich Schiller University Jena, Germany have discovered a molecule that influences the antibiotic-resistance of cholera bacteria. They have published their results in the scientific journal "Nature Communications".
It is largely unknown why influenza infections lead to an increased risk of bacterial pneumonia. Researchers at Karolinska Institutet in Sweden have now described important findings leading to so-called superinfections, which claim many lives around the world every year. The study is published in the journal PNAS, Proceedings of the National Academy of Sciences, and can also contribute to research on COVID-19.
With new insights into how the genetic tool CRISPR - which allows direct editing of our genes - evolved and adapted, we are now one step closer to understanding the basis of the constant struggle for survival that takes place in nature. The results can be used in future biotechnologies.