Scientists from the UNC School of Medicine discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet. The researchers also reported that the NLRP12 gene is underactive in people who are obese, making it a potential therapeutic target for treating obesity and diabetes, both of which are risk factors for cardiovascular disease and other serious conditions.
Weight gain during early childhood is related to the composition of oral bacteria of two-year-old children, suggesting this understudied aspect of a children's collection of microorganisms could serve as an early indicator for childhood obesity.
Scientists continue to unravel links between body weight and the gut microbiome. Now, researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP) report an unexpected finding: mice fed a fatty diet and mannose, a sugar, were protected from weight gain -- and this effect tracked with changes in the gut microbiome. The study published today in Cell Reports.
A new study suggests that defenses against extreme temperatures give E. coli bacteria an advantage in fending off certain drugs. The work could help doctors administer antibiotics in a more precise way.
A Rutgers-led team has discovered how plants harness microbes in soil to get nutrients, a process that could be exploited to boost crop growth, fight weeds and slash the use of polluting fertilizers and herbicides.
Stanford scientists have shown that cellulose serves a mortar-like role to enhance the adhesion of bacteria to bladder cells, causing urinary tract infections.
The use of probiotics is linked to reduced need for antibiotic treatment in infants and children, according to a review of studies that probed the benefits of probiotics, co-led by a Georgetown investigator.
An international collaboration led by scientists has made a key advance toward understanding which of the trillions of gut microbes may play important roles in how humans and other mammals evolve.
If you're looking into the mouth of a brown bear, which is among the world's top predators, your chances of survival probably aren't good. But a team of Rutgers and other scientists has discovered a technology that rapidly assesses potentially lifesaving antibiotics by using bacteria in saliva from an East Siberian brown bear.
Leptospirosis infections, caused by Leptospira bacteria, occur in people and animals around the world, but different strains of the bacteria may vary in their ability to cause disease and to jump between species. Now, researchers reporting in PLOS Neglected Tropical Diseases have for the first time described the characteristics of the Leptospira variants that infect cattle in Uruguay.