Scientists at Fujita Health University, Japan, have discovered how deficiencies of the IL-36Ra protein -- caused by mutations in the IL36RN gene -- delay wound healing via the flooding of the wound with several types of immune cells. However, by inhibiting the functioning of proteins and the signaling pathways involved in activating the immune system at a wound, this delay can be offset. These findings could aid efforts to develop ways of regulating wound healing in IL36RN mutation-related skin disorders.
A team from the George Washington University will present at the American College of Emergency Physicians annual conference, on results of their study exploring the role of Google searches during the early phase of the COVID-19 pandemic in the United States.
Findings from a new study conducted by a team of researchers at Dartmouth's Geisel School of Medicine and published in the journal Preventive Medicine Reports, show that involving pediatric practices in the promotion of private well water testing can influence parental compliance.
A drug-resistant strain of the Neisseria (N.) gonorrhoeae has emerged around the world with the potential to make gonorrhea untreatable. The currently used screening methods for antimicrobial resistant (AMR) determinants are slow, expensive, and not widely available. In an article in The Journal of Molecular Diagnostics researchers report a rapid and cheap method that can provide real-time surveillance to help control the spread of AMR strains of N. gonorrhoeae.
Columbia University Mailman School of Public Health researchers find that strong state firearm laws are associated with fewer firearm homicides--both within the state where the laws are enacted and across state lines. Conversely, weak firearm laws in one state are linked to higher rates of homicides in neighboring states.
T-cells taken from the blood of people who recovered from a COVID-19 infection can be successfully multiplied in the lab and maintain the ability to effectively target proteins that are key to the virus's function, according to a new study published Oct. 26, 2020 in Blood.
Intensive land-use reduces beneficial effects of biodiversity on ecosystem services. This is the main result of a study led by the Helmholtz Centre for Environmental Research (UFZ), the German Centre for Integrative Biodiversity Research (iDiv) and the University of Bern. It assessed the effects of land management on the links between biodiversity, ecosystem functions and ecosystem services, identified thresholds of management intensity, most important species groups for driving services, and the ecosystem services at risk.
Men in jobs with hard physical work have a higher risk of developing dementia compared to men doing sedentary work, new research from the University of Copenhagen reveals. The researchers therefore urge the health authorities to make their recommendations concerning physical activity more specific.
A new study of almost 80,000 children living in urban areas of Catalonia has, for the first time, analysed the relationship between urban exposures and BMI growth trajectories
A research study presented at the ASHG 2020 Virtual Meeting suggests that found that increasing weight is causally protective for breast and prostate cancer.