Live, single-cell imaging shows cellular 'memory' of growth factor availability throughout the cell cycle (and not just snapshot of growth factor availability) influences cells' decision to replicate.
A potential COVID-19 vaccine, delivered by microscopic needles, produces antibodies specific to the virus when tested in mice. This is the first peer-reviewed paper describing a COVID-19 vaccine candidate. The next step is a human clinical trial.
At the BESSY II storage ring, a team has shown how the helicity of circularly polarized synchrotron radiation can be switched faster - up to a million times faster than before. They used an elliptical double-undulator developed at HZB and operated the storage ring in the so-called two-orbit mode. This is a special mode of operation that was only recently developed at BESSY II and provides the basis for fast switching.
Houston Methodist nanomedicine researchers are studying a new drug delivery system that transports oral medication via triglycerides that could eliminate the need for injections or IV treatments of some biologic drugs for rheumatoid arthritis and other autoimmune diseases. They're doing this with a diabetes drug that resulted in approximately 25% absorption in mice models, considered very high for an oral drug. The research will appear in Science Advances April 1.
A paper published in the academic journal Neuro-Oncology by NF experts has demonstrated an increased understanding of low grade gliomas (LGG) occurring in children and adults with NF1.
In a new study, researchers from the University of Copenhagen have mapped how a potent neuropeptide binds to a brain receptor involved in causing human pain. The researchers expect that the mechanism could be exploited as a new avenue for painkilling medicine.
They identified a protein that, like a switch, controls the onset of cell death processes in cancer cells, which are regulated by p53, the protein known as 'the guardian of the genome.' The findings will be used to develop more tailored and effective cancer treatments.
Teprotumumab, the first FDA-approved medicine for thyroid eye disease, provides significant improvement in eye bulging, regardless of patient gender, age or smoking status, according to a study accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.
UC Davis Health physicians and medical staff detail the diagnosis and treatment for first known case of community transmission of COVID-19 in the US. The case reveals how the patient's symptoms matched -- and sometimes varied from -- published studies of COVID-19 infection at the time.
A new study from McGill suggests that, in the right context, some people may experience psychedelic-like effects from placebos alone. The researchers reported some of the strongest placebo effects on consciousness in the literature relating to psychedelic drugs. Indeed, 61% of the participants in the experiment reported some effect after consuming the placebo.