Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for therapeutic actions of an African folk medicine used to treat a variety of illnesses and disorders including diabetes, pain, headaches, paralysis and epilepsy.
Researchers have discovered two key factors behind the intestinal inflammation that plagues people suffering from a disorder that affects their immune system.
Experimental inhibition of this prostanoid led to increased migration of defense cells and production of antimicrobial peptides, resulting in decreased bacterial numbers in the colon.
A new study has found that older patients who were hospitalised were 72 percent more likely to be given a potentially inappropriate prescription after their hospital admission, independent of other patient factors.
Researchers at Tokyo Tech have succeeded in constructing protein nanotubes from tiny scaffolds made by cross-linking of engineered protein crystals. The achievement could accelerate the development of artificial enzymes, nano-sized carriers and delivery systems for a host of biomedical and biotechnological applications.
Researchers investigating new treatments for neuroblastoma -- one of the most common childhood cancers -- have found that a combination of two drugs made tumors disappear in mice, making it more effective than any other drugs tested in these animals. The research is presented at the 30th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland.
New research published in The Journal of Physiology presents a breakthrough in the treatment of Restless Legs Syndrome (RLS).
The researchers explored the efficacy of a multi-therapy approach based on the disease risk factor status specific to individuals with Alzheimer's disease (AD) diagnosis or concern. The findings indicate previously unidentified connectivity between AD risk factors, suggesting that treatment regimens should be tailored to the individual and multi-modal to simultaneously return several risk factors to a normative state.
Around the world, 425 million people live with diabetes and upwards of 15 percent develop foot ulcers, which increases their risk of death 2.5 times. A new nitric oxide-releasing technology has the potential to cut down the healing time of diabetic foot ulcers from 120 days to 21 days.
Scientists from the Helmholtz-Zentrum Dresden-Rossendorf (HZDR), in collaboration with the Monash University Australia, have succeeded in significantly increasing the stability and biocompatibility of special light-transducing nanoparticles. They have developed so-called "upconverting" nanoparticles that not only convert infrared light into UV-visible light, but also are water-soluble, remain stable in complex body fluids, and can be used to store medications. They have created a tool that could potentially make the fight against cancer more effective.