General physicians can deliver medication-assisted therapy for opioid addiction with help from the team members they likely already have in their practices, a new analysis concludes.
University of Guelph researchers have published what is believed to be the first scientific paper in North America on improving medicinal cannabis plant production, helping move the industry into the realm of high-tech laboratories and evidence-based practices. This paper is the first of a series of studies University of Guelph researchers have conducted investigating ideal horticultural practices for indoor cannabis production in response to industry demand.
Scientists at the Department of Energy's Oak Ridge National Laboratory have performed neutron structural analysis of a vitamin B6-dependent protein, potentially opening avenues for new antibiotics and drugs to battle diseases such as drug-resistant tuberculosis, malaria and diabetes. Specifically, the team used neutron crystallography to study the location of hydrogen atoms in aspartate aminotransferase, or AAT, an enzyme vital to the metabolism of certain amino acids.
The opioid epidemic is the most important health issue in West Virginia, above obesity, cancer, chronic obstructive pulmonary disease (COPD) and dental disease, according to a state-based public opinion survey commissioned by Research!America. A strong majority of West Virginians (84 percent) say prescription pain medication abuse and addiction is a major problem in their community, and more than two-thirds (71 percent) say they know someone who experienced pain so severe they sought prescription medicines to treat it.
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a molecular model that may provide a new framework for improving the design of osteoporosis treatments.
Scientists from RUDN University have synthesized a number of new cytotoxic substances - the ones that can damage cells. In the future the results of the study can be used in cancer therapy. The compounds were obtained by domino reaction, a successive formation of several new chemical bonds. The study was published in the Synthesis journal
Research finds the surface texture of microparticles in a liquid suspension can cause internal friction that significantly alters the suspension's viscosity -- effectively making the liquid thicker or thinner. The finding can help address problems for companies in fields from biopharmaceuticals to chemical manufacturing.
Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. A central part of the protective mechanism is an unusual enzyme, PrimPol, which can re-initiate mitochondrial DNA replication after damage.
Osteoporosis is common and affects 1 in 3 women. Calcium is vital for strong healthy bones and worldwide scientific societies have issued guidance about the daily requirements from childhood to old age. The European Menopause and Andropause Society (EMAS) has issued a new clinical guide with the aim of raising awareness of the importance of calcium in lowering the risk of osteoporosis.
Indoloquinoline alkaloids are of great importance due to their unique structure and various biological activities. Several methods have been developed to synthesize indoloquinolines and among those, one-pot methods are of particular importance due to its simplified reaction procedure.