A bone cancer known as osteosarcoma is genetically similar in dogs and human children, according to the results of a study published today by Tufts University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope. The findings could help break the logjam in the treatment of this deadly disease, which hasn't seen a significant medical breakthrough in nearly three decades.
3q29 deletion syndrome is a strong risk factor for both schizophrenia and autism spectrum disorder. People with the rare condition have a distinct neuropsychiatric profile, researchers found.
Researchers have found that a gene known as AEBP1 may play a central role in the development, severity and potential treatment of liver disease, according to a study by Temple University, the Geisinger Obesity Institute and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope. One of the study's major findings is that AEBP1 regulates the expression of a network of at least nine genes related to fibrosis: AKR1B10, CCDC80, DPT, EFEMP1, ITGBL1, LAMC3, MOXD1, SPP1, and STMN2.
Mothers living near more intense oil and gas development activity have a 40-70% higher chance of having children with congenital heart defects (CHDs) compared to those living in areas of less intense activity, according to a new study from researchers at the Colorado School of Public Health.
A quarter of women who have serious maternal complications during childbirth also have premature births, posing a 'dual burden' on families, finds research from NYU Rory Meyers College of Nursing, the University of California, San Francisco (UCSF) California Preterm Birth Initiative, and Stanford University.
Many babies with eczema go on to develop food allergies, asthma and hay fever, and researchers at National Jewish Health say it's not a coincidence. The cracks caused by eczema weaken the skin barrier, allowing allergens to penetrate the skin and cause a sequence of allergic diseases, what experts call the 'atopic march.'
A national study by UC Davis Health researchers finds differences in the decisions to admit or transfer children with mental health emergencies based on the patients' insurance type. Children without insurance are more likely to be transferred to another hospital than those with insurance.
Researchers at the University of Nottingham have discovered that repurposing a heart drug could significantly increase the survival rate for children with ependymoma -- a type of brain tumor.
Scientists created human pancreas on a chip that allowed them to identify the possible cause of a frequent and deadly complication of cystic fibrosis (CF) called CF-Related Diabetes, or CFRD. It may be feasible to also use the small two-chambered device, which features bioengineered human pancreatic organoids to study the causes of non-CF-related conditions such as type 1 and 2 diabetes, according to researchers who report findings in Nature Communications.
A new study has shown that videogames, when used as part of an emotional intelligence training program, can help teenagers evaluate, express, and manage their own emotions immediately after the training.