News by Subject Medicine & Health

An international team led by Montreal researchers discovers two proteins essential to the development of skeletal muscle.

Researchers have been searching for possible treatments for the polio-like illness causing paralysis in children, called acute flaccid myelitis. But a new study shows no signal of efficacy for one potential treatment, the antidepressant fluoxetine. The study is published in the Nov. 9, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.

Statins have been linked with muscle pain and other musculoskeletal adverse events (MAEs) in some patients. A new Pharmacology Research & Perspectives study has examined the timing of MAEs that develop during statin therapy and determined whether concomitant drugs used concurrently with statin therapy shifts the timing of MAEs.

A new study has examined whether managing weight during pregnancy might affect children's bone mass. In the Journal of Bone and Mineral Research study, investigators analyzed prospective data from 2,167 mother-child pairs from Portugal. In under/normal weight mothers, weight gain during pregnancy was associated with slightly increased bone mass at seven years of age in children, while in overweight/obese mothers, no beneficial effect of weight gain on bone mass was observed.

A Musculoskeletal Care study is the first to investigate individual perceptions of the impact of a Pilates exercise program on the daily lives of people with chronic conditions.

A team of researchers writing for the Journal of the American Geriatrics Society suggested that it is important to identify people at risk for falls related to obesity and muscle weakness so that healthcare providers can offer appropriate solutions.

Amyloid-like protein assemblies, long believed to be toxic and fuel diseases like ALS, have been found to play a key role in healthy muscle regeneration.

Three patients with chronic paraplegia were able to walk over ground thanks to precise electrical stimulation of their spinal cords via a wireless implant. In a double study published in Nature and Nature Neuroscience, Swiss scientists Grégoire Courtine (EPFL and CHUV/Unil) and Jocelyne Bloch (CHUV/Unil) show that, after a few months of training, the patients were able to control previously paralyzed leg muscles even in the absence of electrical stimulation.

'Management of Isolated Lateral Malleous Fractures' written by Aimethab A. Aiyer was published in the Journal of the American Academy of Orthopaedic Surgeons.