As we grow older, our muscular function declines. A new study by researchers at Karolinska Institutet in Sweden shows how an unexpectedly high number of mutations in the stem cells of muscles impair cell regeneration. This discovery may result in new medication to build stronger muscles even when in old age. The study is published in Nature Communications.
Researchers studying a rare genetic disorder that causes severe, progressive neurological problems in childhood have discovered insights into biological mechanisms that drive the disease, along with early clues that an amino acid supplement might offer a targeted therapy. The disorder, called TBCK-encephalopathy, disrupts autophagy, an important cellular waste-disposal process.
The Women's Health Initiative found that hormone therapy (HT) use was associated with a reduction in vertebral fracture risk. A new study shows these same benefits may also guard against a woman's risk of developing hyperkyphosis, an exaggerated curvature of the spine that creates a forward stooped posture. Study results are published online today in Menopause, the journal of The North American Menopause Society.
There's a cause of dementia that can sometimes be reversed, but it's often not diagnosed because the symptoms are so similar to those of other disorders. Now researchers say a simple walking test may be able to accurately diagnose the disease, according to a study published the Feb. 21, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
An off-label drug prescribed to treat osteoarthritis of the hand when conventional medication has failed is ineffective, according to new research. The study shows there was no benefit in taking hydroxychloroquine to control debilitating pain when compared to a placebo (dummy substance).
Researchers at UNIGE found that socio-economically disadvantaged individuals in childhood are a greater risk of low muscle strength at an older age. Moreover, this risk is not offset by an improvement in their socio-economic status as adults. This means that inequalities in childhood are biologically embodied to literally 'get into the skin'. Why? They suggest that a physiological deregulation caused by stress in childhood might change the body's ability to maintain good health along time.
New research published in the Journal of Physiology could open the door to new therapies to improve the movement of arms and hands of stroke survivors.
ALS and frontotemporal dementia (FTD) are two neurodegenerative diseases with a toxic relationship, according to a new USC Stem Cell study published in Nature Medicine. The study describes how a mutation in a gene, called C9ORF72, leads to toxicity in nerve cells--causing 10 percent of all cases of ALS, and an additional 10 percent of FTD.
Low muscle strength during the later teen years has been identified as a risk factor for much later onset of the neurological disease known as ALS, or amyotrophic lateral sclerosis. A study at Sahlgrenska Academy published in the Journal of Neurology also links low blood counts at a young age to ALS.
MINNEAPOLIS - A special program that involves balance and eye movement exercises may help people with multiple sclerosis (MS) with their balance problems and fatigue, according to a study published in the Jan. 31, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.