Stem cells have been holding great promise for regenerative medicine for years. However, one of the main limitations in the application of these therapies is the quality of the stem cells that can be generated in the laboratory. Now, a team from the Spanish National Cancer Research Centre (CNIO) has developed a new, simple and fast technology that enhances in vitro and in vivo the potential of stem cells to differentiate into adult cells.
A new thermoplastic biomaterial, which is tough and strong but also easy to process and shape has been developed by researchers at the University of Birmingham.
The aim of this study was to compare the effects of 4-weeks of Traditional Resistance Training versus Plyometric Jump Training programs on the muscular fitness of sedentary and physically inactive participants.
The St. Pölten UAS and the Austrian general accident insurance institution AUVA have made one of the biggest data records for automated gait analysis worldwide openly accessible. Researchers are free to use the data in order to improve automated gait analysis with the help of methods such as machine learning. The dataset and the accompanying description were recently published in the magazine "Scientific Data" of the renowned publishing house Nature.
Scientists from Staffordshire University claim that new 3D printed insoles can significantly improve the foot health of people suffering with diabetes.
A highly sensitive and easy-to-use technique applicable for tissue samples can be useful, for example, to researchers specialised in mitochondrial diseases and cancer.
Women with premature ovarian insufficiency (POI) become estrogen deficient at an early age, which makes them more vulnerable to the loss of bone mineral density. A new study suggests that use of continuous combined oral contraceptives may be especially effective in reducing bone mass loss. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).
Research presents new evidence which strengthens the plausibility that treatment with the novel anti-osteoporotic medicine, romosozumab, may lead to excess cardiovascular complications. Writing in Science Translational Medicine, the authors, from the University of Oxford's Big Data Institute and the Nuffield Department of Population Health, report that by combining data across clinical trials of romosozumab, there is some evidence that use of this drug leads to increased cardiovascular risk.
Using an enzyme inhibitor in meniscus cells, a Penn team was able to soften their nucleus and promote access to previously impassible areas.
Setting out to identify all proteins that make up the sarcomere, the basic contractile unit of muscle cells, resulted in an unexpected revelation, providing experimental evidence that helps explain a fundamental mystery about how muscles work. The research was published in Nature Communications.