Experts at a prestigious medical conference hosted by the American Geriatrics Society (AGS) and funded by the National Institute on Aging (NIA) hope their work --reported today in the Journal of the American Geriatrics Society -- will have colleagues seeing eye-to-eye on an important but under-researched area of health care: The link between impaired vision, hearing, and cognition (the medical term for our memory and thinking capabilities, which are impacted as we age by health concerns like dementia and Alzheimer's disease).
A new outbreak of a rare but preventable eye infection that can cause blindness, has been identified in contact lens wearers in a new study led by UCL and Moorfields Eye Hospital researchers. The research team found a threefold increase in Acanthamoeba keratitis since 2011 in South-East England.
A promising gene therapy for visually impaired sheep is now safe for human trials.
New four-year study data shows the significant impact of a pioneering contact lens management approach to slowing the progression of myopia (nearsightedness) in children, including those whose treatment begins later. CooperVision is presenting the latest outcomes during the BCLA Asia conference in Singapore this week, at which the globally increasing prevalence of myopia is among the most widely discussed issues.
Contrast sensitivity is a measure of how well someone sees an image against a background. Diminished contrast sensitivity can impact daily life because common low-contrast conditions include low light, fog or glare. Understanding what might contribute to a decrease in contrast sensitivity is important. An observational study of nearly 2,000 people taking part in an ongoing study of aging examined whether exposure to the heavy metals cadmium and lead was associated with increased risk of impaired contrast sensitivity.
Many eye diseases exhibit increased permeability of blood vessels in the macular portion of the retina leading to abnormal fluid accumulation and vision loss. Therapies targeting a specific cytokine, VEGF, have transformed clinical care; however, not all patients respond well. A new report in The American Journal of Pathology shows that inhibiting a specific signaling molecule, atypical protein kinase C reduces increased vessel permeability and blocks inflammation. Blocking aPKC may help protect vision in potentially blinding eye diseases.
To see under starlight and moonlight, the retina of the eye changes both the software and hardware of its light-sensing cells to create a kind of night vision. Retinal circuits that were thought to be unchanging and programmed for specific tasks actively adapt to different light conditions, say the Duke scientists who made the discovery.
Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have found that the anti-malaria drug amodiaquine inhibits the apelin receptor protein, which helps drive the vascularization behind diabetic retinopathy, wet age-related macular degeneration (AMD) and other conditions. Because the drug has been approved to treat malaria for decades, it could move relatively quickly through the pipeline to help patients. The study was published in the journal PLOS ONE.
While some rare forms of strabismus have been linked to specific genes, common forms have been hard to pin down genetically. A new genome-wide association study, based on 10 years of work enrolling and studying families with esotropia (cross-eye) is the first step.
Devices to assist individuals with low vision (uncorrectable vision impairment) are not covered by Medicare and many private insurers, although there is evidence that these devices, such as telescopic lenses, magnifiers, large print or talking materials, can improve functioning and quality of life. Little is known about whether sociodemographic disparities exist in the use of low-vision services by Medicare beneficiaries.