Three previously unknown genetic mechanisms have been discovered in causing myopia otherwise known as short or near-sightedness, finds a new study.
This article describes treatment initiatives being undertaken for novel coronavirus 2019 at an ophthalmology center in Singapore.
One-third of COVID-19 patients from Hubei, China, had ocular manifestations, occurring frequently in patients with more severe physical conditions.
Teprotumumab, the first FDA-approved medicine for thyroid eye disease, provides significant improvement in eye bulging, regardless of patient gender, age or smoking status, according to a study accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.
Researchers at Karolinska Institutet and St Erik Eye Hospital in Sweden have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly. Using the CRISPR/Cas9 gene editing, they have also managed to modify the cells so that they can hide from the immune system to prevent rejection. The studies are published in the scientific journals Nature Communications and Stem Cell Reports.
In patients with diabetes, loss of the gland that helps lubricate the eye may be a sign of elevated blood glucose levels, according to research accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting. The study will be published in a special supplemental section of the Journal of the Endocrine Society.
A species of a lipid that naturally helps skin injuries heal appears to also aid repair of common corneal injuries, even when other conditions, like diabetes, make healing difficult, scientists report.
Botulinum toxins are FDA-approved and widely used. Although they are safe and effective, they can drift away from the site of injection, reducing efficacy and causing side effects. New work from Boston Children's Hospital on botulinum B combined structural modeling and genetic engineering to enable the toxin to bind more tightly to nerve cells and stay in place. This led to more effective, longer-lasting local muscle paralysis and reduced toxicity.
A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration (AMD), according to a study from researchers at the National Eye Institute (NEI).
The estimated number of US adults at high risk for vision loss increased from 2002 to 2017 in this observational study based on national survey data. Adults at high risk for vision loss included those who were 65 or older, had a self-reported diagnosis of diabetes, or had eye or vision problems.