Cytochrome c is a small enzyme that plays an important role in the production of energy by mitochondria. It is also involved in signaling dangerous problems that warrant apoptosis, or programmed cell death. Using solid-state NMR, University of Groningen Associate Professor Patrick van der Wel and colleagues from the University of Pittsburgh have discovered that the signal induced by cytochrome c is more controlled than expected. The results were published in the journal Structure.
In a new study published in npj Digital Medicine, a team led by Child Mind Institute researchers report that a wearable tracking device they developed achieves higher accuracy in position tracking using thermal sensors in addition to inertial measurement and proximity sensors. The wrist-worn device, called Tingle, was also able to distinguish between behaviors directed toward six different locations on the head.
A new study from an Iowa State University biomedical researcher describes the biological process that causes Parkinson's-like symptoms to develop following exposure to the metal manganese. The new research, published in the journal Science Signaling, could lead to earlier detection of Parkinson's disease and better outcomes for patients.
A James Cook University scientist is part of an international team that's used new 'big data' analysis to achieve a major advance in understanding neurological disorders such as Epilepsy, Alzheimer's and Parkinson's disease.
Scientists have gained clues into how a Parkinson's disease treatment, called deep brain stimulation, helps tackle symptoms.
The first arm of a phase II clinical trial by a research team at Georgetown University Medical Center testing the use of nilotinib in patients with Parkinson's disease demonstrates precisely how the agent increases levels of dopamine in the brains of study participants.
UC San Francisco researchers have for the first time developed a strategy for targeting a key molecule implicated in Parkinson's disease, opening up a potential new treatment strategy for the currently incurable movement disorder.
A large multi-center study of more than 1,200 patients provides important predictors of Parkinson's disease progression, which will allow better candidate selection for clinical trials and more effective therapy development.
Exercise has potential to improve non-motor as well as motor symptoms of Parkinson's disease (PD), including cognitive function, report investigators in a review published in the Journal of Parkinson's Disease.
Serious diseases are directly linked to the subcortical areas of the brain. Existing treatments for regulating and measuring the activity of the subcortical areas are highly invasive. Researchers from UNIGE decided to see whether a noninvasive method -- electroencephalography -- could be employed in tandem with mathematical algorithms to measure this brain activity externally. They proved for the first time that this technique is able to record signals usually only seen by implanting electrodes in the brain.