Researchers publishing in Current Biology describe the science behind creating lighting to make us all happy and productive indoors. A company is using the technology to create commercial lightbulbs available later this year.
As the day progresses, the strength of the brain's global signal fluctuation shows an unexpected decrease, according to a study published on February 18, 2020 in the open-access journal PLOS Biology by Csaba Orban and a multi-disciplinary team of scientists from the Faculty of Engineering, Yong Loo Lin School of Medicine and N.1 Institute of Health at the National University of Singapore.
A new study of molecular interactions central to the functioning of biological clocks explains how certain mutations can shorten clock timing, making some people extreme 'morning larks' because their internal clocks operate on a 20-hour cycle instead of being synchronized with the 24-hour cycle of day and night. Researchers found that the same molecular switch mechanism affected by these mutations is at work in animals ranging from fruit flies to people.
It is not uncommon for children and teens with autism spectrum disorder to struggle with sleep. To help families, neurologists and other healthcare providers make decisions on the best treatments, the American Academy of Neurology (AAN) has issued a new guideline for sleep problems in children and teens with autism, published in the Feb. 12, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers have discovered through a vast and novel computational library the first molecules that can modulate circadian rhythms by binding with high selectivity to the MT1 melatonin receptor in the brain.
A study of 732,000 accidents over two decades has found that the annual switch to daylight saving time is associated with a 6% increase in fatal car crashes that week.
Several US states have considered doing away with the practice of changing the clocks forward or back in favor of permanent Daylight Saving Time (DST), while experts around the world suggest permanent Standard Time is a better alternative for health and wellbeing. A study appearing Jan. 30 in the journal Current Biology puts forth evidence of another downside of DST: it increases the risk of fatal car accidents for about a week each year.
If you have just had knee, shoulder or hip surgery, you may want to take anti-inflammatories in the morning or at noon, but not at night. A McGill-led study shows, for the first time, that circadian clock genes are involved in healing from surgery. Indeed, the researchers demonstrated that anti-inflammatory medications are most effective in promoting post-operative healing and recovery when taken during the active periods of our biological clocks.
Daily exposure to blue wavelength light each morning helps to re-entrain the circadian rhythm so that people get better, more regular sleep which was translated into improvements in cognitive function, reduced daytime sleepiness and actual brain repair.
A new study suggests that the biological clock is involved in heart toxicity from radiation therapy and could be harnessed as part of a preventive strategy. Findings show that after receiving radiation to the heart, mice with disrupted biological clocks had significantly worse heart function than controls. They also demonstrated that Bmal1--a protein that drives 24-hour rhythms in the expression of many genes--plays an important role in protecting the heart from radiation-related damage.