Researchers from King's College London have shown that how we respond to changes in nutrients at a molecular level plays an important role in the aging process, and this is directed by some key genetic mechanisms.
In the fight against neurodegenerative diseases such as frontotemporal dementia, Alzheimer's and Chronic Traumatic Encephalopathy, the tau protein is a major culprit. Found abundantly in our brain cells, tau is normally a team player -- it maintains structure and stability within neurons, and it helps with transport of nutrients from one part of the cell to another.
Researchers from the University of British Columbia (UBC) and the Central South University (CSU) in China have for the first time identified a gene that increases the risk of Alzheimer's disease.
Amyloid plaque formation directly causes brain tissue loss in animals, but a drug called lithium reduces the life shortening effects of this loss, shows a new study published today in eLife.
UC San Diego researchers discovered that high blood levels of RNA produced by the PHGDH gene could serve as a biomarker for early detection of Alzheimer's disease. The work could lead to the development of a blood test to identify individuals who will develop the disease years before they show symptoms.
Exercise in older adults, even at an advanced stage of dementia, is an important strategy to maintain independence in everyday living and to promote quality of life.
People continuously exposed to air pollution are at increased risk of dementia, especially if they also suffer from cardiovascular diseases, according to a study at Karolinska Institutet in Sweden published in the journal JAMA Neurology. Therefore, patients with cardiovascular diseases who live in polluted environments may require additional support from care providers to prevent dementia, according to the researchers.
To understand what happens in the brain when Alzheimer's disease develops, researchers need to be able to study the molecular structures in the neurons affected by Alzheimer's disease. Researchers at Lund University in Sweden have tested a new imaging method for this purpose. The research is published in the journal Advanced Science.
Taking a low-dose aspirin once a day does not reduce the risk of thinking and memory problems caused by mild cognitive impairment or probable Alzheimer's disease, nor does it slow the rate of cognitive decline, according to a large study published in the March 25, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.
This study used data and brain imaging from a randomized clinical trial for older adults who are cognitively unimpaired and examined brain changes, including the presence of biomarkers for Alzheimer's disease, between those with sleep-disordered breathing and those without.