New science uncovers how an unlikely culprit, Porphyromonas gingivalis (Pg) -- the bacterium commonly associated with chronic gum disease -- appears to drive Alzheimer's disease (AD) pathology.
For people in their 20s and 30s, having blood pressure above normal but below the level considered to be high blood pressure, may be linked to loss of brain volume, according to a study published in the January 23, 2019, online issue of Neurology®, the medical journal of the American Academy of Neurology.
An international team of researchers led by Cortexyme co-founders Stephen Dominy, M.D. and Casey Lynch detail the role of a common bacterium, Porphyromonas gingivalis (Pg), in driving Alzheimer's disease pathology and demonstrate the potential for small molecule inhibitors to block the pathogen.
People with Alzheimer's disease who used antiepileptic drugs had a higher number of accumulated hospital days than people with Alzheimer's disease who did not use antiepileptics, according to a new study from the University of Eastern Finland. People with Alzheimer's disease who used antiepileptic drugs had a higher number of accumulated hospital days than people with Alzheimer's disease who did not use antiepileptics, according to a new study from the University of Eastern Finland.
Research published today (Jan. 22) in the journal Brain reveals a new approach to Alzheimer's disease (AD) that may eventually make it possible to reverse memory loss, a hallmark of the disease in its late stages.
A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer's disease -- even before they show signs of confusion and memory loss, according to a new study from Washington University School of Medicine in St. Louis and the German Center for Neurodegenerative Diseases.
Scientists at the German Center for Neurodegenerative Diseases, the Hertie Institute for Clinical Brain Research and the University Hospital Tuebingen show that a protein found in the blood can be used to precisely monitor disease progression of Alzheimer's long before first clinical signs appear. This blood marker offers new possibilities for testing therapies. The study was carried out in cooperation with an international research team and published in the journal Nature Medicine.
You may have heard that your gut bacteria or 'microbiome' outnumbers your own cells -- but did you know that your microbiome ... has its own microbiome? Or that turning veggie can transform your microbiome in just 24 hours? How about scientists trialing poop transplants for diabetes? A new review in Frontiers in Cellular and Infection Microbiology reveals some surprising facts in its quest to discover: 'what makes a super pooper?'
Older adults concerned about displaying early symptoms of Alzheimer's disease should also consider a hearing check-up, suggest recent findings. What might appear to be signs of memory loss could actually point to hearing issues, says Dr. Susan Vandermorris, one of the study's authors and a clinical neuropsychologist at Baycrest.
MIT researchers have developed a way to dramatically enhance the sensitivity of nuclear magnetic resonance spectroscopy (NMR), a technique used to study the structure and composition of many kinds of molecules, including proteins linked to Alzheimer's and other diseases.