A high-protein, low-calorie diet helps older adults with obesity lose more weight, maintain more muscle mass, improve bone quality and lose 'bad' fat, according to results from a new randomized controlled trial led by Wake Forest University researcher Kristen Beavers.
For the first time, researchers have shown that ordinary human cells can change their original function. This may give new hope for type 1 diabetes patients.
Biology textbooks teach us that adult cell types remain fixed in the identity they have acquired upon differentiation. By inducing non-insulin-producing human pancreatic cells to modify their function to produce insulin in a sustainable way, researchers at the University of Geneva, Switzerland, show for the first time that the adaptive capacity of our cells is much greater than previously thought. Moreover, this plasticity would not be exclusive to human pancreatic cells.
The results of a recent Texas A&M University-led study provide insights into the mechanism by which estrogen can decrease insulin resistance and the production of glucose, reducing incidences of Type 2 diabetes mellitus.
A University of Virginia School of Medicine researcher will provide updates on a UVA-developed artificial pancreas -- including early results from a nationwide clinical trial -- during a presentation at the AAAS Annual Meeting. The presentation from Boris Kovatchev, PhD, director of the UVA Center for Diabetes Technology, is scheduled for 1:30-2 p.m. Feb. 15.
Finding new treatments or a cure for type I diabetes has been elusive in part because scientists have not had a reliable animal model that mimics the full scope of human type I diabetes. A research team at The University of Toledo has developed a humanized mouse model that spontaneously develops Type I diabetes and the full range of complications experienced by diabetes patients. That allows study of the disease and its natural progression in a way not previously possible.
Researchers at University of Utah Health detailed the function of cone snail insulins, bringing them one step closer to developing a faster-acting insulin to treat diabetes.
Using a novel mouse model, Joslin researchers demonstrate that impaired insulin signaling in the brain negatively affects cognition, mood and metabolism, all components of Alzheimer's disease.
Researchers have shown that targeted silencing of microRNA-132, which is over-expressed in type 2 diabetes, can result in improved insulin secretion and reduced blood glucose in mice and increased insulin secretion in isolated human islet cells.
An MIT-led research team has developed a drug capsule that could be used to deliver oral doses of insulin, potentially replacing the injections that patients with type 2 diabetes have to give themselves every day.