New team-based care guided by a personalized risk score for heart failure patients reduced the mortality rate of high-risk heart failure patients by nearly 50 percent, according to new research from the Intermountain Medical Center Heart Institute in Salt Lake City.
In the largest genetic study of Alzheimer's disease, researchers at the University of California, San Francisco and Washington University School of Medicine in St. Louis, have found that genes that increase risk of cardiovascular disease also heighten the risk for Alzheimer's.
Genetics may predispose some people to both Alzheimer's disease and high levels of blood lipids such as cholesterol, a common feature of cardiovascular disease, according to a new study by an international team of researchers led by scientists at UC San Francisco and Washington University School of Medicine in St. Louis.
Autoimmune diseases such as psoriasis, lupus and rheumatoid arthritis more than double the risk of cardiovascular disease. A new study shows that immune cells that arise during autoimmune disease cause cholesterol to become trapped inside blood vessels.
A new condition, that occurs in the presence of both sarcopenia and obesity and termed as '[sarcopenic obesity', and that describes under the same phenotype the increase in body fat mass deposition, and the reduction in lean mass and muscle strength.
Risk factors of type 2 diabetes and cardiovascular disease accumulate in children who have poor aerobic fitness, a new study from the University of Eastern Finland shows. The study also found that the traditional way of expressing aerobic fitness in proportion to total body mass overestimates the role of aerobic fitness in identifying children at an increased risk of these diseases.
Following a Mediterranean diet low in calories and engaging daily physical activity have proved to reduce body weight and cardiovascular risk in patients with overweight and metabolic syndrome, and to maintain these benefits after one year. These are the main findings of the PREDIMED-Plus trial, which have studied more than 600 patients aged between 55 and 75 years old with obesity or overweight and metabolic syndrome.
Researchers at the University of Georgia have found that a high-fat diet enriched with cottonseed oil drastically improved cholesterol profiles in young adult men.
A hallmark of atherosclerosis is its complex pathogenesis, which is dependent on altered cholesterol metabolism and inflammation. A number of studies characterized transcriptomics of macrophages following interaction with modified LDL, and revealed alteration of the expression of genes responsible for inflammatory response and cholesterol metabolism. The researchers attempted to identify the main mater regulator genes in macrophages treated with atherogenic modified LDL using a bioinformatics approach.
To the great surprise of cancer researchers in a Georgetown University-led study, a protein they investigated for its possible role in cancer turned out to be a powerful regulator of metabolism.