An individualised and family-based physical activity and dietary intervention reduced the plasma LDL cholesterol concentration of primary school children, a new study from the University of Eastern Finland shows.
Researchers of Universitat Rovira I Virgili and Harvard Medical School have demonstrated the association between the consumption of omega 3 and the reduction in the risk of suffering cardiovascular events through the analysis of lipoprotein samples from 26,034 women, the largest and most detailed study ever carried out.
Patients with high lipid levels have an increased risk for ischemic events, despite statin therapy. Findings presented as late-breaking science during the SCAI 2020 Scientific Sessions Virtual Conference revealed that for statin-treated patients with elevated triglycerides and increased cardiovascular risk, icosapent ethyl significantly reduced first and subsequent revascularizations compared with placebo.
Researchers discovered the 3D structure and mode of action of DGAT1, the enzyme that synthesizes triglycerides.
Case management is an effective, collaborative, and cost-effective way to help frequent users of health care services integrate all aspects of their care. The research team behind this study developed a program theory to investigate how, and in what circumstances, case management in primary care works to improve outcomes among frequent users who have chronic conditions.
A scientific team found a new metabolism regulation system for the brown adipose tissue using the kallikrein-kinin hormonal system, so far related to the physiology of the renal and cardiovascular system and inflammation and pain processes. This molecular auto-control system of lipidic metabolism, so far unknown, could help prevent the damaging effects derived from an excessive activation of the brown adipose tissue.
Obese Europeans who are treated with cholesterol lowering drugs have not only lower values of blood LDL cholesterol and markers of inflammation but in addition a more healthy gut bacteria profile than those obese who are not prescribed statins. This is reported in a new study in Nature by the EU-funded MetaCardis consortium.
A new study by the University of South Florida Health Morsani College of Medicine and the University of Alabama at Birmingham profiled bioactive lipids in blood samples from hospitalized black and white patients soon after a heart attack. The preliminary research indicates that bioactive lipid mediators -- key to cardiac repair differences in blacks and whites after heart attack -- may offer new targets for more personalized diagnosis and treatment of heart failure.
By combining the fine-grained detail available from animal studies with the statistical power of genetic studies involving hundreds of thousands of human genomes, researchers have discovered a new gene involved in regulating the body's cholesterol.
Body fat is linked to many different conditions beyond diabetes. This research could be important for understanding the risk factors for other metabolic diseases, such as fatty liver disease and atherosclerosis, and even non-metabolic diseases that are increased by obesity, such as cancer and Alzheimer's disease.