Susceptibility to obesity, insulin resistance and other cardio-metabolic traits may also be dependent on a person's sex. An international research team studied sex differences and sex-specific interaction with the genetic background in cardio-metabolic phenotypes. The researchers discovered, among other things, a sex-specific obesity locus of the Lypla1 gene, which is associated with human obesity. The results of the study have now been published in Cell Metabolism.
Laminitis -- a complex, common and often devastating disease -- is the second biggest killer of domestic horses. Now a body of important research on it, from QUT and other organizations, has been compiled and shared online by the Equine Veterinary Journal for vets and others to access.
Researchers have identified a rare type of cancer cell that cannot make cholesterol, a key nutrient. By targeting this deficiency, scientists may be able to develop new strategies for treating the disease.
Setbacks in drug trials aiming to raise HDL have led researchers to reassess the particle's effects on heart health. A study in the Journal of Lipid Research combining proteomics and mouse genetics may help researchers understand researchers understand the proteins in the particle, how they get there and how they determine HDL function.
A high-protein, low-calorie diet helps older adults with obesity lose more weight, maintain more muscle mass, improve bone quality and lose 'bad' fat, according to results from a new randomized controlled trial led by Wake Forest University researcher Kristen Beavers.
For the first time, researchers have shown that ordinary human cells can change their original function. This may give new hope for type 1 diabetes patients.
Biology textbooks teach us that adult cell types remain fixed in the identity they have acquired upon differentiation. By inducing non-insulin-producing human pancreatic cells to modify their function to produce insulin in a sustainable way, researchers at the University of Geneva, Switzerland, show for the first time that the adaptive capacity of our cells is much greater than previously thought. Moreover, this plasticity would not be exclusive to human pancreatic cells.
The results of a recent Texas A&M University-led study provide insights into the mechanism by which estrogen can decrease insulin resistance and the production of glucose, reducing incidences of Type 2 diabetes mellitus.
Animal experiments have shown that caloric restriction causes cellular changes that can prevent diseases, the subject of a session at FAPESP Week London.
A University of Virginia School of Medicine researcher will provide updates on a UVA-developed artificial pancreas -- including early results from a nationwide clinical trial -- during a presentation at the AAAS Annual Meeting. The presentation from Boris Kovatchev, PhD, director of the UVA Center for Diabetes Technology, is scheduled for 1:30-2 p.m. Feb. 15.