Systemic amyloidosis is a major cause of renal injury, mostly due to direct kidney damage caused by deposits of abnormal protein called amyloid, in the kidney parenchyma. In patients with cardiac amyloidosis, renal infarction is associated with acute kidney injury according to a new study in Mayo Clinic Proceedings, published by Elsevier. Investigators recommend that a diagnosis of renal infarction should be systematically considered in patients with unexplained acute kidney injury in the context of cardiac amyloidosis.
Physiotherapists from James Cook University in Australia say simple pelvic floor exercises may be a cure for some common problems men experience in the bedroom.
A new finding by researchers at The University of Texas at Dallas and UT Southwestern Medical Center shows that several species of bacteria reside in bladder tissue of postmenopausal women who experience recurrent urinary tract infections (RUTIs). The results, published online April 17 in the Journal of Molecular Biology, represent the first systematic analysis of biopsies from patients in this population.
A new computational tool -- a single-patient classifier -- effectively enables physicians to assign a bladder cancer subtype to an individual patient's cancer using that patient's genomic data.
University of California San Diego School of Medicine researchers report that men treated with medications for benign prostatic hyperplasia (enlarged prostate) experienced a two-year delay in diagnosis of their prostate cancer and were twice as likely to have advanced disease upon diagnosis.
Dartmouth researchers have introduced an inexpensive DNA-based test for human papillomavirus (HPV), the cause of cervical cancer, in Honduras. The test aid can effectively be used to screen women who have never been screened for this deadly disease. Results of the initiative revealed not only high positivity rates of HPV but unexpected differences in the types of HPV compared to those found in the US.
Many people have heard that drinking cranberry juice can help prevent urinary tract infections (UTIs). Although clinical trials of this popular folk remedy have produced mixed results, some studies have shown that drinking cranberry juice can keep bacteria that cause UTIs from sticking to cells lining the urinary tract. Now, researchers reporting in ACS' Journal of Natural Products have identified cranberry oligosaccharides in the urine of cranberry-fed pigs that could be responsible for this activity.
Latest results from a project to discover what makes a cancer patient more likely to suffer adverse side effects after radiotherapy have shown that a combination of biological markers and certain genetic changes can predict radiation sensitivity. The research is presented at ESTRO 38.
A single high dose of radiation that can be delivered directly to the tumor within a few minutes is a safe and effective technique for treating men with low-risk prostate cancer, according to a study presented at the ESTRO 38 conference.
Renal fibrosis, the abnormal accumulation of fibrotic material within the kidney, hinders kidney function and may lead to eventual renal failure. Using genetically altered mice, researchers from Duke University investigated the mechanisms of interaction between the T cells, angiotensin receptors (AT1), and macrophages to understand their role in impeding renal fibrosis. A report in The American Journal of Pathology, published by Elsevier, suggests that selectively activating AT1 receptors on T cells may help treat renal fibrosis.