Brazilian researchers observed that in uninfected adipocytes, the hormone irisin altered the expression of genes that regulate ACE-2, which encodes a protein to which the virus binds in order to invade human cells.
Using patient data from Cleveland Clinic's COVID-19 registry, Dr. Joe Zein found that receiving the flu vaccine does not increase risk for COVID-19 or worsen associated disease outcomes, suggesting it is safe and advisable to receive the influenza vaccine this flu season.
Responding to the COVID-19 pandemic caused by the novel coronavirus, SARS-CoV-2, requires models that can duplicate disease development in humans, identify potential targets and enable drug testing. Specifically, access to primary human lung in vitro model systems is a priority since a variety of respiratory epithelial cells are the proposed targets of viral entry.
Researchers at the University of Malaga study how '4-PBA' treatment modulates the inflammatory response in severe cases of COVID-19
Authors of this editorial review the evidence for the management of patients with the acute respiratory distress syndrome (ARDS) that may apply to patients with severe COVID-19, what has been learned about treatment of these patients, and the gaps in knowledge that remain.
The vast majority of Twitter users who vape with JUUL e-cigarettes are not using the devices to stop smoking or to improve their health, according to a research team led by University of Utah Health scientists. The researchers say this finding, which challenges JUUL's stated mission of improving smokers' lives, could help hone anti-smoking and vaping efforts targeted at Twitter users, particularly underage teens.
The COVID-19 pandemic has increasing numbers of doctors caring for patients virtually. While critical to protecting patient health during a pandemic, however, virtual care presents unique challenges, especially when it comes to diagnosis. Now, cardiologists at the Lewis Katz School of Medicine at Temple University, have come up with a virtual screening tool that greatly simplifies the process of diagnosing a complex form of heart failure known as pulmonary hypertension.
Project led by researchers from Brazilian and American institutions will collect primary data during the pandemic to create a repository that will serve as a basis for future studies. The findings of the comparative analysis will be published in book form.
Changes in lung cancer treatment during the COVID-19 pandemic were evaluated in this study.
E-cigarette, or vaping, associated lung injury (EVALI) has sickened thousands of people, most under the age of 35. Studies have linked vitamin E acetate, an oily substance in some vaping liquids, to the disorder. Now, researchers reporting in ACS' Chemical Research in Toxicology have uncovered a possible mechanism: Vitamin E acetate could increase the fluidity of lung surfactant, causing the surfactant layer to collapse, contributing to symptoms such as shortness of breath and lung inflammation.