Research from the University of Liverpool, published in Lancet Respiratory Medicine, identifies a genetic variant that could improve the safety and effectiveness of corticosteroids, drugs that are used to treat a range of common and rare conditions including asthma, and chronic obstructive pulmonary disease (COPD).
The popularity of electronic cigarettes (e-cigarettes) has grown rapidly in the United States over the past decade. E-cigarettes may help cigarette smokers quit smoking, but they may also encourage transitions to start smoking cigarettes. Based on available evidence, Dartmouth researchers quantified the balance of health benefits and harms associated with e-cigarette use at the population level and found that e-cigarettes could substantially increase the number of adolescents and young adults who eventually become cigarette smokers.
A set of comprehensive asthma management tools helps decrease asthma-related visits to the emergency department, urgent care or hospital and improves patients' asthma control.
An iPad app that educates patients about different options for colon cancer screening and allows them to order their preferred test may increase screening rates.
Illnesses and injuries associated with working in Illinois mines are substantially underreported to the federal agency tasked with tracking these events, according to a new study published in the American Journal of Industrial Medicine.
A more intensive biomedical research approach is necessary to control and ultimately eliminate tuberculosis (TB), according to a perspective published in The American Journal of Tropical Medicine and Hygiene. In the article, authors Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases, and Robert W. Eisinger, Ph.D., special assistant for scientific projects at NIAID, discuss the need to modernize TB research by applying new diagnostic, therapeutic, and vaccine approaches.
Researchers report discovery of a strong predictive biomarker for bronchopulmonary dysplasia, and they show a role for the biomarker in the pathogenesis of this neonatal lung disease. These results open the path to possible future therapies to prevent or lessen BPD, which is marked by inflammation and impaired lung development, and mortality or morbidity.
A discovery by Melbourne researchers could help to identify patients with a particularly aggressive type of lung cancer that are likely to respond to immunotherapies currently used in the clinic to treat other cancers. The research has also revealed a unique molecular signature in the blood that could, in the future, be used to detect these aggressive lung cancers with a simple blood test.
Halting the voyage of gut bacteria to the brain could help prevent harmful brain inflammation after a sepsis infection, a new study shows.
Researchers at UC Davis Health and Albany Medical College have shown that the protein vascular endothelial growth factor A -- or VEGFA -- plays a major role in the inflammation and airway obstruction associated with asthma. The finding may eventually lead to new asthma treatments targeting VEGFA.