New research reveals rising rates of liver cancer around the world, despite advances aimed at preventing the disease. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society (ACS).
New study finds gene therapy improved cardiac, muscle and liver function in Danon disease mouse models.
MIT biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system on a microfluidic chip seeded with human cells. With this 'organs-on-a-chip' model, they could explore the role of immune cells in ulcerative colitis and other inflammatory diseases.
Research on mice reveals the surprising impact on fat metabolism and the role played by a regulator protein in the liver.
Today, there is no effective way to treat liver fibrosis. In a new study, researchers from University of Southern Denmark present a new technology to investigate the cellular processes as they change during fibrosis development. Key findings are being validated in studies of human patients, paving the way for possible novel diagnostics and treatments.
Researchers at Osaka City University Graduate School of Medicine introduced sorafenib to patients with advanced stages of the liver cancer hepatocellular carcinoma (HCC) and measured the amount of 16 circulating soluble immune checkpoint proteins. Their data suggest that a high amount of sBTLA proteins may be a marker of overall survival in patients with HCC.
A study published in the journal Nature Microbiology identified factors that the hepatitis B virus uses when establishing long-term infection in the liver. The findings could help lead to treatment strategies for chronic HBV infection, a condition that increases the risk of developing liver cancer and is responsible for almost 900,000 deaths worldwide each year.
While there is an association between liver fibrosis and heart failure, the mechanisms for this association are currently unclear but may be of particular importance for people living with human immunodeficiency virus (HIV) and/or hepatitis C, both of which are chronic infections that affect the liver and heart.
In two new papers published online in Gastroenterology, investigators from China describe the impact of coronavirus on the digestive tract. Here are the key findings.
In the past two decades, death rates after liver transplantation have dropped by more than half in the UK, according to a recent analysis of almost 10,000 liver transplant recipients published in BJS (British Journal of Surgery).