Researchers have discovered two key factors behind the intestinal inflammation that plagues people suffering from a disorder that affects their immune system.
A combination of two drugs, which prompt the body's immune system to identify and kill cancer cells, is a safe treatment for patients with advanced non-small cell lung cancer and has shown some signs of efficacy. The research is presented at the 30th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland.
Early results from a phase I trial in a small group of patients with advanced cancer using two drugs (nivolumab and pixatimod) that stimulate the immune system report that patients with bowel cancer may benefit from the combination. The research is presented at the 30th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland.
Children exposed to diesel-dominated air pollution in London are showing poor lung capacity, putting them at risk of lifelong breathing disorders, according to a study led by Queen Mary University of London, King's College London & University of Edinburgh
'Pancreatic Cancer Across Europe,' published by United European Gastroenterology (UEG) to coincide with World Pancreatic Cancer Day, examines the past and current state of pancreatic cancer care and treatment, as well as the future prospects, such as targeting the microbiome, for improving the prognosis for patients. Whilst lung, breast and colorectal cancer have seen significant reductions in death rates since 1990, deaths from pancreatic cancer continue to rise.
People living in colder regions with less sunlight consume more alcohol and experience more alcoholic liver disease.
National Institutes of Health scientists and their collaborators found that hepatitis B virus (HBV)-associated acute liver failure (ALF) -- a rare condition that can turn fatal within days without liver transplantation -- results from an uncommon encounter between a highly mutated HBV variant and an unusual immune response in the patient's liver that is mainly sustained by antibody-producing B cells.
The fifth-leading risk factor for mortality worldwide, air pollution presents a major heart health risk. A simple intervention could help people breathe easier at home.
In castration-resistant prostate cancer, the tumors continue to progress even though testosterone production has been blocked; more than 90% of these patients develop metastasis and the survival rate is one to two years. * Using liquid biopsy, a simple blood test has been successful in determining what type of treatment can help to prolong the life expectancy of more than 150 patients
A research team based in Japan led by Kanazawa University has demonstrated the effect of osteopontin on hepatitis C virus replication and interferon signaling in cancer stem cells. Their research sheds light on a novel therapeutic target for treating hepatocellular carcinoma.