Chemist Vincent Rotello at UMass Amherst, with others at University College London, have developed a 'quick and robust' blood test that can detect liver damage before symptoms appear, offering what they hope is a significant advance in early detection of liver disease. Details appear in Advanced Materials. Their new method can detect liver fibrosis, the first stage of liver scarring that can lead to fatal disease if left unchecked, from a blood sample in 30-45 minutes.
A quick and robust blood test that can detect liver damage before symptoms appear has been designed and verified using clinical samples by a team from UCL and University of Massachusetts.
National guidelines assume that all patients who're diagnosed with clinical sepsis in an emergency department will be admitted to the hospital for additional care, but new research has found that many more patients are being treated and released from the ED for outpatient follow-up than previously recognized.
A new technique to study fat stores in the body could aid efforts to find treatments to tackle obesity, research from the University of Edinburgh suggests. The approach focuses on energy-burning tissues found deep inside the body -- called brown fat -- that help to keep us warm when temperatures drop.
UCLA scientists have identified specific gut bacteria that play an essential role in the anti-seizure effects of the ketogenic diet -- research published today in the journal Cell. The study is the first to establish a causal link between seizure susceptibility and the gut microbiota -- the 100-trillion-or-so bacteria and other microbes that reside in our intestines.
MIT researchers have built an ingestible sensor equipped with genetically engineered bacteria that can diagnose bleeding in the stomach or other gastrointestinal problems.
The controversial Severe Sepsis and Septic Shock Early Management Bundle study adds weight to the belief that early lactate measurements can make a big difference. This follow-up study found a two percent increase in mortality for each hour of delay in patients with an abnormal lactate value.
Scientists have found a connection between bacteria in the gut and antitumor immune responses in the liver. Bacteria found in the gut of mice affect the liver's antitumor immune function. The findings have implications for understanding the mechanisms that lead to liver cancer and for therapeutic approaches to treat them.
University of Colorado School of Medicine's Karim C. El Kasmi, MD, PhD, assistant professor of pediatrics, and Ronald Sokol, MD, professor of pediatrics, are authors of an article in the April 2018 Nature Communications that sheds light on the underlying cause of intestinal failure-associated liver disease and suggests new therapeutic approaches.
Some examples of the persistence of incompletely resolved issues in asthma management are: 1) misdiagnosis -- with the related complex consequences --, especially in children population and, 2) poor control of the disease. Also related factors as suboptimal medical management , poor education and health literacy of patients, poor adherence and elevated costs for patients and healthcare systems are some other factors that need urgent implementation.