A new study from the University of California, Irvine shows that compounds in both green and black tea relax blood vessels by activating ion channel proteins in the blood vessel wall. The discovery helps explain the antihypertensive properties of tea and could lead to the design of new blood pressure-lowering medications.
Collecting liver tissue from 22 postoperative patients with long-term post-Fontan surgery, researchers have found a specific liver fibrosis to develop from the sinusoidal region which is difficult to accurately assess by conventional examination methods (ultrasound elastography and blood tests).
Researchers assessed the number of hospital admissions for noncommunicable diseases (abnormal tissue growths, metabolic diseases, cardiovascular diseases and musculoskeletal diseases) in São Paulo, Brazil, between January and June last year compared with the corresponding periods in the previous three years.
Diphtheria - a relatively easily-preventable infection - is evolving to become resistant to a number of classes of antibiotics and in future could lead to vaccine escape, warn an international team of researchers from the UK and India.
Participants with obesity and food insecurity lost less weight than food secure participants with obesity over 24 months when following an intensive, lifestyle-based intervention for weight loss. These findings suggest that weight loss approaches that address both obesity and food insecurity are needed. Findings from a post hoc analysis of the PROPEL (Promoting Successful Weight Loss in Primary Care in Louisiana) study are published in Annals of Internal Medicine.
Wearing a protective face mask has only a modest effect on the ability of healthy people to do vigorous exercise, according to a study published today in the European Respiratory Journal. This suggests that masks could be worn safely during intense exercise, for example to reduce COVID-19 transmission between people visiting an indoor gym.
Canadian Scientists and Swiss Surgeons discover the cause of excess post-surgical scarring. The finding could improve recovery from abdominal and pelvic surgery. The research published in Science, was conducted in mice and shows the excess scarring is caused by macrophages. The researchers also discovered two ways to inhibit this natural response. Macrophages are also present in humans. The team hopes to move to trials on human cells, soon, and eventually clinical trials.
Studies of the microbiome in the human gut have largely overlooked non-bacterial microbes: viruses, protists, archaea and fungi. Now research in mice points to a significant role for fungi, called the mycobiome, in the intestine. "We showed that the gut mycobiome of healthy mice was shaped by the environment, including diet, and that it significantly correlated with metabolic outcomes," said Kent Willis, M.D.
Artificial intelligence can already scan images of the eye to assess patients for diabetic retinopathy, a leading cause of vision loss, and to find evidence of strokes on brain CT scans. But what comes next?
Adhesions are scars in the abdomen, which can occur after surgery, often have serious consequences. Now, researchers from the University of Bern and Inselspital, University Hospital Bern, in collaboration with Canadian researchers, have discovered how such adhesions form. The findings may help to develop a drug to prevent adhesions in the future. The study was published as the cover story of Science magazine.