A team of UC Davis Health scientists and physicians has identified a cellular connection between diabetes and one of its major complications -- blood vessel narrowing that increases risks of several serious health conditions, including heart disease and stroke.
A study that looked at data on more than 900,000 VA patients showed that elevated blood glucose levels detected in routine outpatient tests, though well below diagnostic thresholds, predicted diabetes within 5 years.
Patients with cystic fibrosis who take ivacaftor appear to have fewer respiratory infections over time than those not taking the drug, according to new research published online in the Annals of the American Thoracic Society.
Aging men with low testosterone levels who take testosterone replacement therapy (TRT) are at a slightly greater risk of experiencing an ischemic stroke, transient ischemic attack (TIA), or myocardial infarction, especially during the first two years of use, reports a study appearing in The American Journal of Medicine, published by Elsevier. The findings confirm concerns voiced by many health agencies about the potential risks associated with the treatment.
Scientists at the University Würzburg and University Hospital of Würzburg found that megakaryocytes act as 'bouncers' and thus modulate bone marrow niche properties and cell migration dynamics. The study was published in July in the journal Haematologica.
Scientists created human pancreas on a chip that allowed them to identify the possible cause of a frequent and deadly complication of cystic fibrosis (CF) called CF-Related Diabetes, or CFRD. It may be feasible to also use the small two-chambered device, which features bioengineered human pancreatic organoids to study the causes of non-CF-related conditions such as type 1 and 2 diabetes, according to researchers who report findings in Nature Communications.
One of the most commonly performed surgeries to treat stress urinary incontinence in women may have better long-term results than another common surgical technique, according to a study led by Mayo Clinic researchers. The retrospective study of more than 1,800 cases at Mayo Clinic from 2002 to 2012 found that the need for additional surgery was twice as high after a transobturator sling surgery compared with a retropubic sling procedure.
University of Colorado Cancer Center study published in Breast Journal argues against combined approach: Patients undergoing coordinated breast and gynecologic procedures had a significantly longer length of hospital stay, and higher complication, readmission, and reoperation rates compared with patients who underwent single site surgery.
An Australian study has demonstrated that cannabis-based medication helps tackle dependency on cannabis, one of the most widely used drugs globally. A paper about the University of Sydney and NSW Health clinical trial provides the first strong evidence that cannabis replacement therapy could reduce the rate of relapse. The principles are similar to nicotine replacement in that the patient is provided a safer drug and in an environment that helps break the pattern of use.
An observational study based on a group of smokers and former smokers in France looked at whether electronic cigarette use was associated with changes in the number of cigarettes smoked, with smoking cessation rates among smokers, and with smoking relapse among former smokers.