California researchers have discovered that a medication used to prevent and treat malaria may also be effective for Zika virus. The drug, called chloroquine, has a long history of safe use during pregnancy, and is relatively inexpensive. The research was published today in Scientific Reports.
Children vaccinated against influenza are significantly less likely to experience serious complications from the virus that could land them in hospital, new research from Public Health Ontario (PHO) and the Institute for Clinical Evaluative Sciences (ICES) has found.
Scientists have identified a set of biomarkers that indicate which patients infected with the Ebola virus are most at risk of dying from the disease. The results come from one of the most in-depth studies ever of blood samples from patients with Ebola. Researchers found 11 biomarkers that distinguish fatal infections from non-fatal ones and two that, when screened for early upon symptom onset, accurately predict which patients are likely to die.
Given the critical role livestock play in Mongolia, transmission of tick-borne diseases can have very real health and economic implications for livestock and herders. George Mason University's Dr. Michael von Fricken and colleagues explored the interaction between nomadic herders, the livestock they own, and the tick-borne diseases they are exposed to.
Scientists have elucidated the Zika burden in a Brazilian metropolis. Their data indicate: the outbreak may be coming to an end and further outbreaks in the region seem unlikely. The study has also provided new evidence supporting the link between Zika infection during pregnancy and malformations in newborns. A third finding is important with regard to intervention measures: Zika virus infection predominantly affects poor regions.
New research could boost the development of a more potent vaccine against the global killer.
Birth defects in babies born infected with Zika virus remain a major health concern. Now, scientists suggest the possibility that some women in high-risk Zika regions may already be protected and not know it. New research in PLOS Pathogens on Nov. 16, performed in mice, shows women who develop symptom-free Zika infections may be able to acquire immunity that would protect them from future infections and their offspring in a future pregnancy.
In a comprehensive and complex molecular study of blood samples from Ebola patients in Sierra Leone, published today (Nov. 16, 2017) in Cell Host and Microbe, a scientific team led by the University of Wisconsin-Madison has identified signatures of Ebola virus disease that may aid in future treatment efforts.
Researchers at The University of Texas at Austin are developing a new tool for liquid biopsy that can detect RNA biomarkers from cancer cells in a patient's blood much more accurately and completely than other existing methods. This could soon provide doctors with a more complete picture of an individual's disease, improving their chances of finding the best treatment, while also sparing patients the pain, inconvenience and long wait times associated with surgical biopsies.
Researchers have uncovered a sequence of biological processes that occur in humans infected with the bacterium Mycobacterium tuberculosis as the infection progresses to pulmonary tuberculosis, according to new research published in PLOS Pathogens.