In 2000, measles was declared to be eliminated in the United States. Today, the US and many other countries are experiencing outbreaks of measles because of declines in measles vaccine coverage. Without renewed focus on vaccination efforts, the disease may rebound in full force, according to a commentary in NEJM by infectious diseases experts at the National Institute of Allergy and Infectious Diseases and Penn State University College of Medicine's Milton S. Hershey Medical Center.
A team of researchers from Versailles Saint-Quentin-en-Yvelines University (UVSQ), Inserm and Pasteur Institute (Unité Mixte de Recherche 1181 Biostatistique, biomathématique, pharmacoépidémiologie et maladies infectieuses - B2PHI) has been able to provide for the first time an accurate estimate of both the incidence (annual number of new cases) and added direct cost of infections due to antibiotic-resistant bacteria in patients hospitalised in French hospitals during 2015 and 2016.
Extracts from the seeds of the Ginkgo biloba tree show antibacterial activity on pathogens that can cause skin infections such as acne, psoriasis, dermatitis and eczema.
Antiretroviral therapy (ART) is usually effective at suppressing HIV, allowing the immune system to recover by preventing the virus from destroying CD4+ T cells. Scientists have now identified a rare, paradoxical response to ART called extreme immune decline, or EXID. Five individuals evaluated at the NIAID experienced a significant decline in CD4+ T cell levels despite suppression of HIV below detectable levels for more than three years, according to a report published in JCI Insight.
Scientists from Lancaster University have discovered that immune responses originally found to prevent fungal infections are also important in eliminating Trichinella spiralis, a round worm and the causative agent of Trichinosis. People acquire trichinellosis by consuming raw or undercooked meat infected with the Trichinella parasite, particularly wild game meat or pork.
New research suggests that the microbial communities associated with chronic wounds common in diabetic patients affect whether those wounds heal or lead to amputations.
New research sheds light on how a hepatitis B viral protein stimulates the expansion of immune cells that impair antiviral responses, according to a study published April 18 in the open-access journal PLOS Pathogens by Haitao Guo of the Indiana University School of Medicine, Bin Wang and Jiming Zhang of Fudan University, and colleagues. The findings potentially explain how the hepatitis B virus (HBV) establishes and maintains chronic infection, and could lead to the development of novel therapeutic strategies.
University of Sydney researchers have developed a model that can predict salmonella outbreaks several months in advance, and its results come as a warning ahead of the Easter long weekend.
A new study led by a research team from Massachusetts Eye and Ear and Harvard Medical School describes how bacteria adapted to the modern hospital environment and repeatedly cause antibiotic-resistant bloodstream infections. This study examined one of the first sustained hospital outbreaks of a multidrug-resistant bacterium, Enterococcus faecalis, which occurred from the early through the mid-1980s, causing over 60 outbreak strains.
A study of samples from 92 patients with cystic fibrosis (CF) has revealed that certain bacteriophages -- viruses that infect bacteria -- worsen the severity of bacterial infections associated with the disorder.