Study results released today by the HIV Prevention Trials Network (HPTN) show long-acting injectable cabotegravir (CAB LA) to be well tolerated by men and women and support the dosing schedule currently being used in a phase 3 HPTN study for HIV prevention.
Scientists from Princeton University have successfully tested a cell-culture system that will allow researchers to perform laboratory-based studies of long-term hepatitis B virus (HBV) infections with the goal of testing new therapies.
A two-year clinic-based HIV testing program in Zimbabwe failed to diagnose many cases of HIV in children in the surrounding area, Dr. Victoria Simms from the London School of Hygiene & Tropical Medicine, UK, and colleagues, report in PLOS Medicine.
Initiating antiretroviral therapy (ART) on the same day as HIV testing is feasible and leads to improved retention and health outcomes, according to a trial published in PLOS Medicine.
Most of the 500,000 annual deaths worldwide from influenza are due to influenza pneumonia. Understanding how the transition to pneumonia occurs could shed light on interventions that could reduce that number. Research from the University of Cincinnati takes a different approach to how flu spreads through the lungs by focusing on how resistant or susceptible cells lining the airway are to viral infection.
For decades, vaccine manufacturers have used chicken eggs to grow the flu virus strains included in the seasonal vaccine. But because these human strains frequently mutate to adapt to their new environment, the resulting vaccine is often an imperfect match to the virus that it is supposed to protect against. Duke researchers have devised a way to keep the human influenza virus from mutating during egg-based production, generating a perfect match to the target vaccine.
The raccoon that topples your trashcan and pillages your garden may leave more than just a mess. More likely than not, it also contaminates your yard with parasites -- most notably, raccoon roundworms (Baylisascaris procyonis).
Human cytomegalovirus (CMV) is a common virus found worldwide. When CMV infects fetuses, it can cause serious complications such as hearing difficulties and mental retardation in affected infants. A group of researchers have evaluated for the first time the efficacy of maternal universal screening using CMV IgG avidity tests for congenital CMV infection, and they have also identified issues with the current maternal CMV screening methods.
An article published by JAMA Pediatrics estimates the number of measles cases in U.S. children and the associated economic costs under different scenarios of vaccine hesitancy, which is the delay or refusal to vaccinate based on nonmedical personal beliefs.
An innovative new study takes a network theory approach to targeted treatment in rural Africa, and finds that a simple algorithm may be more effective than current policies, as well as easier to deploy, when it comes to preventing disease spread -- by finding those with 'most connections to sick people.'