Stanford University researchers report that injecting mice with inactivated induced pluripotent stem cells (iPSCs) launched a strong immune response against breast, lung, and skin cancers. The vaccine also prevented relapses in animals that had tumors removed. The work appears in the journal Cell Stem Cell on Feb. 15.
Scientists are now equipped with a more detailed picture of the human immune system's response to influenza vaccination, thanks to the results of a new investigation.
Scientists at The Scripps Research Institute (TSRI) have achieved a major milestone toward designing a safe and effective vaccine to both treat heroin addiction and block lethal overdose of the drug.
New injectable delivery system forms a non-inflammatory depot that can continuously release drug carriers for months at a time after a single administration.
Analysis of more than 38,000 children in Ghana shows that all-cause mortality is significantly lower in children who received the measles vaccine after the third diphtheria-tetanus-pertussis (DTP) vaccination. The study adds to growing evidence that, when administered in the WHO recommended sequence, measles vaccination provides non-specific benefits to child survival. The findings have implications for achieving the Millennium Development Goal 4 of reducing child mortality.
As the fight against drug-resistant infections continues, University of Leeds scientists are looking back at previously discarded chemical compounds, to see if any could be developed for new antibiotics.
Researchers are paving the way toward a new therapeutic approach for gonorrhea by shedding light on the mechanism behind important proteins on the Neisseria gonorrhoeae bacteria's outer membrane.
Research on HIV has led to many promising ideas for vaccines to prevent infection by the AIDS virus, but very few candidate vaccines have been tested in clinical trials. One reason is the technical difficulty of manufacturing vaccines based on the envelope proteins of the virus, according to vaccine expert Phil Berman, who has now developed new methods for the production of HIV vaccines.
Vaccines have enormous impact not just on health, but on keeping people out of poverty, according to a new study led by researchers from Harvard T.H. Chan School of Public Health. They estimated that increased investments in 10 vaccines administered in low- and middle-income countries over a 15-year period could avert up to 36 million deaths and 24 million cases of medical impoverishment.
In a new study appearing in the February issue of Health Affairs, Angela Chang of Harvard University and coauthors looked at immunization programs for vaccines -- estimating that as many as 36 million deaths and 24 million cases of medical impoverishment in forty-one low- and middle-income countries eligible for support from Gavi, the Vaccine Alliance, would be averted by vaccines administered in the period 2016-30.