Current vaccination policies may not be sufficient to achieve and maintain measles elimination and prevent future resurgence in Australia, Ireland, Italy, the UK and the US, according to a study published in the open access journal BMC Medicine.
Antiviral antibodies produced by survivors of Ebola infection continue to evolve and improve after recovery, according to a study of immune responses in four people who received care at Emory University Hospital in 2014. High levels of neutralizing antibodies- thought to be key to protecting someone against deadly infection -- didn't appear in patients' blood until months after they left the hospital.
The quantity and quality of antibodies recognizing the end region of the malaria parasite's CSP protein is a good marker of protection by the RTS,S/AS01E vaccine, shows a study led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by 'la Caixa.' The results provide valuable information for guiding the design of future, more effective vaccines.
MIT researchers have used machine-learning algorithms to discover a secondary mechanism that helps some antibiotics kill bacteria. This mechanism involves disrupting bacterial metabolism of nucleotides that the cells need to replicate their DNA.
A new analysis co-led by The Johns Hopkins University identified 25 United States counties that are most likely to experience measles outbreaks in 2019. The analysis combined international air travel volume, non-medical exemptions from childhood vaccinations, population data and reported measles outbreak information.
A country's progress towards measles elimination can be mapped on a 'canonical path' that in turn can guide vaccination strategies, according to a study from scientists at the Johns Hopkins Bloomberg School of Public Health.
A new HIV vaccine delivery strategy appears to enhance the protective immune response in a preclinical model. Scientists at the La Jolla Institute for Immunology (LJI) have discovered that delivering an HIV vaccine in small doses over a series of days leads to a stronger immune response than when the same vaccine is given all at once.
After comparing a series of compositionally identical yet structurally different vaccines by testing them on multiple animal models, Northwestern University researchers found the structure of SNAs in one vaccine dramatically outperformed the others, which ranged from ineffective to nearly curative.
Orally administered vaccine can protect millions from hepatitis B. Oral vaccines are both safer and less expensive than injections. Therefore, researchers are continuously pursuing ways to produce an oral vaccine that is sufficiently effective. Now, University of Copenhagen physicists have delivered virologists a 'recipe' for improving vaccine drops using methods from the world of nanophysics.
Dartmouth researchers have introduced an inexpensive DNA-based test for human papillomavirus (HPV), the cause of cervical cancer, in Honduras. The test aid can effectively be used to screen women who have never been screened for this deadly disease. Results of the initiative revealed not only high positivity rates of HPV but unexpected differences in the types of HPV compared to those found in the US.