Allergens are widespread, but highly variable in U.S. homes, according to the nation's largest indoor allergen study to date. Researchers from the National Institutes of Health report that over 90 percent of homes had three or more detectable allergens, and 73 percent of homes had at least one allergen at elevated levels. The findings were published November 30 in the Journal of Allergy and Clinical Immunology.
Survivors of the first known Ebola outbreak, which occurred in the Democratic Republic of the Congo in 1976, may be key to development of vaccines and therapeutic drugs to treat future outbreaks. UCLA researchers located the 14 Ebola survivors of the 1976 outbreak who, in January 2016, were still living in the same small, remote villages in the forests of the Équateur Province of northwestern Democratic Republic of the Congo.
In the not-too-distant future, nanoparticles delivered to a cancer patient's immune cells might teach the cells to destroy tumors. A flu vaccine might look and feel like applying a small, round Band-Aid to your skin. These are examples of how innovative biomaterials could enhance vaccines against HIV and other infectious diseases and immunotherapies for patients with cancer or dampen responses in autoimmune disorders, allergies and transplanted organ recipients. A review appears in Trends in Immunology.
Lactic acid bacteria, commonly used as probiotics to improve digestive health, can offer protection against different subtypes of influenza A virus, resulting in reduced weight loss after virus infection and lower amounts of virus replication in the lungs, according to a study led by Georgia State University.
St. Jude Children's Research Hospital and Emory University research offers insight into origins of the T cells that provide enduring immune protection; findings should aid vaccine development and cancer immunotherapies.
Scientists from UTMB and Biomed Protection predicted which H3N2 variants would become 'vaccine resistant', and this prediction has been confirmed during the 2017 Australian flu season. The results published suggest that the current flu vaccine will work better during the 2018 US flu season than the 2017 Australian flu season.
Men who have never engaged in sexual intercourse are still at risk for acquiring HPV, according to a study published recently in the Journal of Infectious Diseases by researchers at the University of Texas Health Science Center at Houston School of Public Health.
What distinguishes memory CD8 T cells from untrained naive cells is that they can respond rapidly, within minutes or hours. The new research illuminates how they do it -- their genes are poised to respond, even years after initial activation.
Autophagy allows cells to degrade and recycle their cellular components. Researchers at UZH have now demonstrated that the autophagy machinery in certain immune cells leads to the immune system attacking the central nervous system. The researchers are using these findings as a basis to look into new approaches to treating autoimmune diseases such as multiple sclerosis.
A blood test using infrared spectroscopy can be used to diagnose two types of cancer, lymphoma and melanoma, according to a study led by Georgia State University.