Urgent shortage of evidence for safe withdrawal from antidepressants
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A new study has highlighted that while much is known about the ever increasing uptake of antidepressant medications around the world, there is very little evidence on safe and effective approaches to discontinuing treatment.
Penn Medicine researchers discovered that less is more when it comes to the length of what is known as the single-chain variable fragment for CAR T cells.
A portion of people with the scleroderma develop pulmonary arterial hypertension, which can cause the heart to weaken and fail. Current screening methods may miss one in three patients with this sometimes fatal complication. But one computer algorithm, according to this study, will significantly improve the accuracy and help physicians treat it earlier.
An analysis of published studies indicates that pharmacist-led efforts can reduce medication-related harms -- such as cognitive impairment, falls, drug-drug interactions, and bacterial infections -- in older adults in residential aged care facilities. The findings are published in the British Journal of Clinical Pharmacology.
A new analysis of data from a randomised controlled trial of the stop-smoking drug varenicline (brand name Chantix in the US and Champix elsewhere), has provided clear evidence that varenicline does not increase the risk of psychiatric problems.
An award-winning Scientific Electronic Exhibit to be presented at the ARRS 2021 Virtual Annual Meeting found no statistically significant threshold for increased renal transplant biopsy risk based on systolic, diastolic, or mean arterial (MAP) blood pressure alone.
An award-winning Scientific Electronic Exhibit to be presented at the ARRS 2021 Virtual Annual Meeting found non-contrast pituitary MRI for central precocious puberty, growth hormone deficiency, and short stature has similar diagnostic yield compared to the standard contrast-enhanced protocol.
Recent growth in the number of healthcare workers providing home care for Medicare patients is "small and inadequate" compared with the increasing demand in an aging America, a new study suggests.
Researchers at Penn Medicine have identified more genetic mutations that strongly predispose younger, otherwise healthy women to peripartum cardiomyopathy (PPCM), a rare condition characterized by weakness of the heart muscle that begins sometime during the final month of pregnancy through five months after delivery. PPCM can cause severe heart failure and often leads to lifelong heart failure and even death.
What The Study Did: Researchers investigated the association of burnout at an academic medical center with clinician type, sex, work culture and use of electronic health records.