A new study from the Marine Biological Laboratory indicates that lifespan extension at lower temperatures is not just a matter of turning down the thermostat. Rather, the extent to which temperature affects lifespan depends on an individual's genes.
Researchers found that excitatory neurons -- those that are more likely to trigger an action (as opposed to inhibitory neurons, which are less likely to prompt neural activity) -- are more vulnerable to accumulations of abnormal tau protein, which is increasingly being implicated in Alzheimer's disease.
A new study from the University of Pennsylvania School of Nursing's Center for Health Outcomes and Policy Research (CHOPR) describes the quality of end of life care in nearly 500 US hospitals, utilizing nearly 13,000 bedside nurses as informants of quality. The study has been published online first. It will also be in a future issue of the Journal of the American Geriatrics Society.
Research in mouse cells identifies defective metabolic pathway in aging immune T cells. The pathway is critical for switching T cells from dormancy into illness-fighting mode. In experiments, researchers restored lagging T-cell function by adding small-molecule compounds. Findings suggest possible mechanism behind weakened immunity common in the elderly.
Patients with arthritis in their knees experienced significant improvement in pain and mobility after undergoing a weekly, whole-body massage for two months, according to a study led by researchers at Duke Health.
In an effort to better understand frontotemporal dementia, an international team of researchers, led by Washington University School of Medicine in St. Louis, has found that a lone mutation in a single gene that causes an inherited form of the disorder makes it harder for neurons in the brain to communicate with one another, leading to neurodegeneration.
University of Alberta scientists have identified three biomarkers for detecting mild cognitive impairment and Alzheimer's disease in saliva samples. The research has promising results for application in a clinical setting.
A new study links hearing loss with an increased risk for mortality before the age of 75 due to cardiovascular disease. Researchers found that mortality among those with hearing loss is elevated, particularly among men and women younger than age 75 and those who are divorced or separated. However, mortality risk was diminished in adults with a well-hearing partner. This is the first study to investigate the combined effects of hearing loss with partnership, parental status, and increased mortality risk.
3D printing can cut the cost of adaptive aids that help people with hand arthritis. Current products are quite expensive, and more so to create customized versions, but 3D printing drops the cost by an average of 94 percent for 20 different handheld devices.
A new study published in the journal Sexual Medicine indicates that sexual activity is associated with improved wellbeing amongst older adults, measured through higher enjoyment of life scores.