Scientists from the University of California, Irvine School of Biological Sciences have discovered how to forestall Alzheimer's disease in a laboratory setting, a finding that could one day help in devising targeted drugs that prevent it. The researchers found that by removing brain immune cells known as microglia from rodent models of Alzheimer's disease, beta-amyloid plaques -- the hallmark pathology of AD -- never formed. Their study will appear Aug. 21, 2019 in the journal Nature Communications.
The association between type 2 diabetes and increased fracture risk is well documented. However, little was known about the possible effect of family history of diabetes on bone mineral density (BMD). A study from China now confirms that a history of first-degree family members with diabetes is linked to increased BMD as well as to insulin resistance. Results are published online in Menopause, the journal of The North American Menopause Society (NAMS).
Rutgers and other scientists have discovered how brown fat, also known as brown adipose tissue, may help protect against obesity and diabetes. Their study in the journal Nature adds to our knowledge about the role of brown fat in human health and could lead to new medications for treating obesity and type 2 diabetes.
Biomedical engineers at Duke University have discovered that an adenosine receptor called A2B can be pharmaceutically activated to reverse bone degradation caused by osteoporosis in mouse models of the disease.
Survivors from a wide range of cancers could experience increased risks of heart disease and blood circulation problems compared to those who have never had cancer, according to new estimates published in the Lancet.
Older adults are enthusiastic adopters of ridesharing technology. Access to on-demand ride sharing improves their access to health care and improves their overall quality of life. However, the cost remains a challenge.
A study of the world's oldest, continuously-studied birth cohort tracked blood pressure from early adulthood through to late life and explored its influence on brain pathologies detected using brain scanning in their early 70s.
Changes in blood pressure in those as young as 36 are linked to markers of poorer brain health in later life, finds UCL-led research involving participants of Britain's oldest running birth cohort study.
Researchers in Umeå, Sweden, have presented a model that explains why memory deteriorates as the body ages. With age, the brain receives an increased load from the heart's beating as the body's large arteries stiffen over the years, causing damage to the smallest blood vessels in the brain.
A University of California, Irvine-led study has found that online brain game exercises can enable people in their 70s and even 80s to multitask cognitively as well as individuals 50 years their junior. This is an increasingly valuable skill, given today's daily information onslaught, which can divide attention and be particularly taxing for older adults.