Research out today in the journal Cell shows that a specific change in the SARS-CoV-2 coronavirus virus genome, previously associated with increased viral transmission and the spread of COVID-19, is more infectious in cell culture.
Two variants of the novel coronavirus (SARS-CoV-2), called G614 and D614, were circulating in mid-March. A new study shows that the G version of the virus has come to dominate cases around the world. They report that this mutation does not make the virus more deadly, but it does help the virus copy itself, resulting in a higher viral load, or "titer," in patients.
An analysis of patient records in Canada provides important new insights into changing patterns of inpatient healthcare utilization. Between 2007 and 2016, standardized hospitalization rates declined for coronary artery and vascular disease, heart rhythm disorders, stroke, and heart failure but increased for some important conditions: acquired valvular heart disease; vascular cognitive impairment; and congenital heart disease. The study appears in the Canadian Journal of Cardiology, published by Elsevier.
States with the highest level of income inequality had a larger number of COVID-19-related deaths compared with states with lower income inequality. For instance, New York state, with the highest income inequality, had a mortality rate of 51.7 deaths per 100,000. This is 125 times greater than Utah, the state with the lowest income inequality and which had a mortality of 0.41 per 100,000 at the end of the period studied.
Since COVID-19's spread to the United States earlier this year, death rates in the U.S. have risen significantly. But deaths attributed to COVID-19 only account for about two-thirds of the increase in March and April, according to a study published Wednesday in the Journal of the American Medical Association.
Using same-day traffic volumes for March 2019 and March 2020 across Florida, researchers examined the relationship of key governmental requests for public isolation and travel limitations. Results show the drastic changes in human behavior during the onset of the pandemic. Traffic volumes by March 22, 2020, dropped by 47.5% compared to that same point in 2019. Moreover, traffic declined in March 2020 corresponding with the governor's state of emergency declaration and school, restaurant, and bar closures.
A team led by Case Western Reserve University medical researchers has developed a potential treatment method for Pelizaeus-Merzbacher disease (PMD), a fatal neurological disorder that produces severe movement, motor and cognitive dysfunction in children. It results from genetic mutations that prevent the body from properly making myelin, the protective insulation around nerve cells.
A new study shows that SARS-CoV-2, the virus that causes COVID-19 (coronavirus), can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus. The discovery, published today in the journal Cell Reports Medicine, was made using heart muscle cells that were produced by stem cell technology.
Today, 30 June 2020, the Research Data Alliance publishes the final version of the RDA COVID-19 Recommendations and Guidelines for Data Sharing covering four research areas - clinical data, omics practices, epidemiology and social sciences. This document is also complimented by overarching areas focusing on legal and ethical considerations, research software, community participation and indigenous data.
A researcher in KU's Center for Excellence in Health Communications to Underserved Populations surveyed Kansans over a 96-hour window to gauge where they got coronavirus info. He found they trusted the governor's briefing, local and national media most, while trusting social media the least.