Recent Ebola virus disease (EVD) outbreaks highlight the need for licensed treatments. ZMapp, an experimental therapy, has shown promise in a clinical trial, but targets only one of five known species of Ebola virus. Now NIAID-supported scientists have discovered powerful, broadly neutralizing antibodies (bNAbs) in the blood of EVD survivors. In animal studies, two of these antibodies provided substantial protection against disease caused by the three species known to cause fatal human illness.
People who have their evening meal before 9 p.m. or wait at least two hours before going to sleep have lower risk of breast and prostate cancer.
The estimates for global tuberculosis deaths by the World Health Organisation (WHO) and the Institute for Health Metrics and Evaluation (IHME) differ considerably for a dozen countries, according to a study led by ISGlobal. The results highlight the need to improve the modeling approaches in these countries in order to understand the true burden of the disease and design adequate health policies.
Canadian researchers document the health problems that precede a diagnosis of multiple sclerosis.
Thirteen patients with OXA-48-producing Klebsiella pneumoniae ST392 have been reported by Sweden and Norway between January and April 2018 -- all returning travelers with prior hospital admission in Gran Canaria. Whole genome sequencing showed tight clustering between the bacterial isolates from the cases.
A nationwide investigation of the prevalence and distribution of ticks and exposure to tick-borne diseases highlights the value of public participation in science. The study, published on July 12 in the open-access journal PLOS ONE, was conducted by Nathan Nieto of Northern Arizona University and colleagues, and funded by Bay Area Lyme Foundation.
Countries have traditionally been divided into two broad categories according to their capacity to innovate. Now, researchers reporting in PLOS Neglected Tropical Diseases say these categories are overly simplistic and leave out the key roles that a group of Innovative Developing Countries (IDCs) play in the public health arena.
HIV-positive children in South Africa are more likely to have developmental disabilities compared to children who are HIV negative. HIV-positive children ages 4 to 6 had nearly four times the odds of delays in sitting, standing, walking, and speaking, and more than twice the odds of a hearing disability and cognitive delay compared to HIV-negative children.
A large-scale study published by researchers from Royal Holloway University of London has drawn together the findings of a decade of agrochemical research to confirm that pesticides used in crop protection have a significant negative impact on the learning and memory abilities of bees.
A new study by the Prevention Research Center of the Pacific Institute for Research and Evaluation examines the relationship between the number and location of alcohol outlets (such as bars or liquor stores or other places where alcohol is sold) and traffic crashes.