Working with colleagues from the German Center for Neurodegenerative Diseases (DZNE ), Harvard Medical School and Ohio State University, researchers from Charité - Universitätsmedizin Berlin have shown that the increased incidence of infections seen in spinal cord injury patients is directly linked to a disruption of the normal central nervous system.
A discovery about the endoplasmic reticulum in hormone-producing cells shed lights on water balance under normal physiology and could open doors to better understanding of diseases related to misfolded proteins.
Previous research has shown that the protein histone deacetylase 3, or HDAC3, turns off the genes that encourage the stem cells in our bone marrow to make and store fat instead of making bone. As HDAC3 levels decrease naturally with age, bones become less dense and easily breakable. Now scientists looking further upstream to hopefully explain the mechanism behind that process are finding some conflicting results.
Almost 11 percent of Medicare participants with diabetes had very low blood sugar levels that suggested they were being over-treated, a new study finds. But only 14 percent of these patients had a reduction in blood sugar medication refills in the next six months.
People with chronic kidney disease may be especially vulnerable to the deleterious effects of poor sleep, according to a new paper published in the Journal of the American Society of Nephrology.
Unsuccessful courtship attempts by males create aversive memories that can reduce their level of enthusiasm for subsequent courtship attempts. Scientists at UC Riverside and colleagues have attempted to understand this behavior at the molecular level. Using the fruit fly as a model organism, the researchers show that the body's hormonal state is critical to the maintenance of such "courtship memories." Two hormones and dopamine, a neurotransmitter, are required in the brain to maintain courtship memories.
A majority of patients with type 1 diabetes who were treated with dapagliflozin, a type 2 diabetes medicine, had a significant decline in their blood sugar levels, according to a new study published in The Lancet Diabetes and Endocrinology.
The Journal of Nuclear Medicine's September supplement shines a spotlight on theranostics and its increasingly important role in delivering precision medicine. Theranostics refers to the combination of a predictive biomarker, identified through diagnostic imaging using radiolabeled ligands (which lock onto the specific cancer cell receptor/biomarker), with precise therapy targeted on the now-marked cancer cells. The cancer cells are destroyed, while healthy cells are unharmed -- minimizing side effects and improving quality of life for patients.
The Endocrine Society today issued a Clinical Practice Guideline on the treatment for gender-dysphoric/gender-incongruent people, commonly referred to as transgender, to develop the physical characteristics of the affirmed gender.
Research published today shows that light from RayVio's 293nm ultraviolet (UV) LED is more efficient than sunlight at producing vitamin D3 in skin samples.