A new tool for analyzing tissue damage seen on MRI brain scans can detect with more than 70% accuracy early signs of cognitive decline, new research shows.
A new artificial intelligence-based score considers multiple factors to predict the prognosis of individual patients with COVID-19 seen at urgent care clinics or emergency departments. The tool, which was created by investigators at Massachusetts General Hospital, can be used to rapidly and automatically determine which patients are most likely to develop complications and need to be hospitalized.
A Morgridge imaging study of macrophages -- immune cells that are important to human health, but paradoxically can help some cancers grow and spread -- is offering better ways to understand these cells and target them with immunotherapies.
A drug-resistant strain of the Neisseria (N.) gonorrhoeae has emerged around the world with the potential to make gonorrhea untreatable. The currently used screening methods for antimicrobial resistant (AMR) determinants are slow, expensive, and not widely available. In an article in The Journal of Molecular Diagnostics researchers report a rapid and cheap method that can provide real-time surveillance to help control the spread of AMR strains of N. gonorrhoeae.
A test to diagnose two very serious diseases such as ALS and FTD when the pathologies have not yet appeared: a new methodology succeeds in detecting the protein TDP-43 - the same that accumulates in the brain of patients - even when it is present in minute quantities in the body. Since there are currently no treatments that can interfere with the course of the two diseases, early detection could be of great help to develop useful drugs and understand their dynamics
Dual-organ system enables the measurement of cardiac toxicity arising from breast cancer chemotherapy. A collaborative team, which includes a group from the Terasaki Institute for Biomedical Innovation, has developed an organs-on-a-chip system that more widely examines the responses of breast cancer and heart tissues to therapeutic breast cancer drugs.
In a new study presented at the ASHG 2020 Virtual Meeting, researchers investigated the prevalence of disease-causing variants in established breast cancer predisposition genes in women over age 65.
An analysis of information from a large U.S. cancer database indicates that patients with liver cancer from rural regions and lower income households often have more advanced cancer at the time of diagnosis and face a higher risk of death compared with other patients. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society (ACS).
Researchers develop a new method to isolate specific cells, and in the process find a more robust fluorescent protein.
A new study led by Marc Veldhoen, principal investigator at Instituto de Medicina Molecular with an interdisciplinary team of clinicians and researchers from FMUL and CHLN and collaborators at IPST, shows that 90% of subjects have detectable antibodies 40 days up to 7 months post contracting COVID-19. These results, now published in the scientific journal European Journal of Immunology, also show that age is not a confounding factor in levels of antibodies produced, but disease severity is.