Women who engaged in 30 minutes per day of light physical activity had a 12 percent lower risk of death, while women did a half-hour each day of moderate to vigorous activity had a 39 percent lower mortality risk.
A drug used to treat schizophrenia has the potential to slow the progression of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease for which there is currently no effective cure. After six years of research on several animal models and a few patients, Canadian researchers discovered that pimozide stabilizes the disease in the short term. A clinical trial must confirm the efficacy and safety of the drug before it is offered to patients.
The first genetic mutation that appears to protect against multiple aspects of biological aging in humans has been discovered in an extended family of Amish living in Indiana, reports a new study. An experimental 'longevity' drug that recreates the effect of the mutation is now being tested in human trials to see if it provides protection against aging. Indiana Amish with the mutation live 10 percent longer, are protected from diabetes and have a younger cardiovascular system.
Researchers at The Ohio State University Wexner Medical Center have come up with a new device, proven safe and effective, to treat diastolic heart failure.
By focusing on genetic variations within a primary tumor, differences between the primary and a metastatic tumor, and additional diversity from tumor DNA in the blood stream, physicians can make better treatment choices for patients with gastric and esophageal adenocarcinoma. This study challenges current guidelines and supports evaluation of metastatic lesions and circulating tumor DNA.
As health delivery moves away from disease-based models to person centred delivery, a study led by Dr Helen Lloyd at the University of Plymouth addresses the development of a new practical tool to support organisations and practitioners in delivering this new approach
88.2 percent of patients receiving pharmacoscopy-guided treatment achieved partial or complete remission, compared to 23.5 percent to their own previous treatment. Further, the median progression-free survival increased four-fold. Retrospectively, pharmacoscopy also predicted the response of AML patients to first-line treatment with 90 percent accuracy. These results show that pharmacoscopy can assist decision-making of the responsible clinicians effectively and thus represent a powerful tool for practical precise and personalized medicine.
Machine learning could improve our ability to determine whether a new drug works in the brain, potentially enabling researchers to detect drug effects that would be missed entirely by conventional statistical tests, finds a new UCL study published in Brain.
A stem cell therapy did not improve walking ability in people with peripheral artery disease, although exercise did lead to significant improvements, according to a new study. This is the largest trial of this type of therapy in people with blockages in leg arteries. Scientists were disappointed that stem cell therapy didn't improve walking, because earlier research suggested it could be beneficial.
Using virtual reality therapy to improve arm and hand movement after a stroke is equally as effective as regular therapy, according to a study published in the Nov.15, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.