'What has been missing in clinical trials may just be the timing of the treatments,' says first author Lynsey Fettig.
A study that included 150 veterans with chronic low back pain found that those who completed a 12-week yoga program had better scores on a disability questionnaire, improved pain intensity scores, and a decline in opioid use. The findings jibe with those from two past clinical trials involving non-veterans.
An overwhelming majority of Americans (86%) agree that health care professionals should discuss clinical trials with patients diagnosed with a disease as part of their standard of care, according to a new national public opinion survey commissioned by Research!America. And three-quarters of respondents (75%) agree that taking part in clinical trials is as valuable to our health care system as giving blood.
Study results released today by the HIV Prevention Trials Network (HPTN) show long-acting injectable cabotegravir (CAB LA) to be well tolerated by men and women and support the dosing schedule currently being used in a phase 3 HPTN study for HIV prevention.
The dapivirine vaginal ring, which had been found safe and to help protect against HIV in two Phase III trials in African women, was shown to be safe and acceptable in a study of US teen girls. Regulatory approval is being sought for the ring in women ages 18-45; the new study provides data that would be needed for expanding approval to include girls under age 18, one of the highest-risk groups in Africa.
For patients undergoing surgery to repair a bunion deformity of the foot, non-weight-bearing x rays taken immediately after surgery can provide a good estimate of the risk that the bunion will return over time, reports a study in the current issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.
New research offers a possible explanation for why a new type of cancer treatment hasn't been working as expected against bladder cancer.
Investigators at the National Cancer Institute and the Children's Oncology Group announce the opening of enrollment for NCI-COG Pediatric MATCH, a unique precision medicine clinical trial to explore whether targeted therapies can be effective for children and adolescents with solid tumors that harbor specific genetic mutations and have progressed during or after standard therapy.
The antiretroviral drug dapivirine contained in a vaginal ring for HIV prevention, is absorbed in very low concentrations into breastmilk, according to a US study of the dapivirine ring in women who were no longer nursing their babies but still producing milk. Researchers are now planning studies of the ring in African women who are breastfeeding as well as during pregnancy, when there may be a greater risk of acquiring HIV.
The Cardiovascular Research Foundation (CRF) is pleased to announce that the first issue of Structural Heart: The Journal of the Heart Team is now available online.