Administration of nitric oxide gas during and for 24 hours following heart surgery decreased the risk of patients developing acute and chronic kidney problems, a randomized, controlled trial conducted in China found.
Investigators have identified a new cellular pathway that may help explain how arterial inflammation develops into atherosclerosis -- deposits of cholesterol, fats and other substances that create plaque, clog arteries and promote heart attacks and stroke. The findings could lead to improved therapies for atherosclerosis, a leading cause of death worldwide.
Using transcranial magnetic stimulation and network control theory, researchers have taken a novel approach to understanding how signals travel across the brain's highways and how stimulation can lead to better cognitive function.
Eating foods high in salt is known to contribute to high blood pressure, but does that linear relationship extend to increased risk of cardiovascular disease and death? Recent cohort studies have contested that relationship, but a new study published in the International Journal of Epidemiology by investigators from Brigham and Women's Hospital and their colleagues using multiple measurements confirms it.
Microelectrodes can be used for direct measurement of electrical signals in the brain or heart. These applications require soft materials, however. With existing methods, attaching electrodes to such materials poses significant challenges. A team at the Technical University of Munich (TUM) has now succeeded in printing electrodes directly onto several soft substrates.
Bisexual men have a higher risk for heart disease compared with heterosexual men across several modifiable risk factors, finds a new study published online in the journal LGBT Health.
A discovery about how human cells are 'triggered' to undergo an inflammatory type of cell death could have implications for treating cancer, stroke and tissue injury, and immune disorders. A research team from the Walter and Eliza Hall Institute in Melbourne identified the molecular trigger in human cells that drives necroptosis, and implicated defects in this molecular trigger as potentially playing a role in cancer development.
This Scientific Statement addresses gaps in resuscitation training that lead to flat survival rates for cardiac arrest victims. Standardized online and in-person courses are falling short and not always implemented to optimize retention and mastery. The statement examines best practices in education and applies the learning in new resuscitation science, offering suggestions for improvement in training on eight key elements.
A new study shows that a caffeine concentration equivalent to four cups of coffee promotes the movement of a regulatory protein into mitochondria, enhancing their function and protecting cardiovascular cells from damage. The work, by Judith Haendeler and Joachim Altschmied of the Medical Faculty, Heinrich-Heine-University and the IUF-Leibniz Research Institute for Environmental Medicine in Duesseldorf, Germany, and colleagues, publishes June 21 in the open access journal PLOS Biology.
In an effort to improve stroke recognition and reduce life-threatening pre-hospital delays worldwide, researchers at Penn Medicine created a universal stroke awareness program, Stroke 112.