Researchers at the University of Oulu in Finland have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism (SNP) rs11672691 influences prostate cancer aggressiveness. Their findings also suggest ways to improve risk stratification and clinical treatment for advanced prostate cancer. The study is published in the journal Cell.
Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common. The study lays the foundation for finding new ways to treat prostate cancer, particularly for the most aggressive forms of the disease.
People who received complementary therapy for curable cancers were more likely to refuse at least one component of their conventional cancer treatment, and were more likely to die as a result, according to researchers from Yale Cancer Center and the Cancer Outcomes, Public Policy and Effectiveness Research Center (COPPER) at Yale School of Medicine. The findings were reported today online in JAMA Oncology.
A study detected in tumoral tissue hundreds of RNAs that do not encode proteins but appear to regulate effects of androgens and androgen receptors on gene expression in tumors. By investigating the connection between the presençe of these molecules and tumor aggressiveness, the research paves the way for new scientific approaches focusing on the transcription process of noncoding RNA.
A new International Journal of Cancer study reveals that eating an early supper and having a long interval between the last meal and sleep are associated with lower breast and prostate cancer risks.
Previous research has shown that cannabinoids can help lessen side effects of anti-cancer therapies. Now a new British Journal of Pharmacology review has examined their potential for the direct treatment of cancer.
People who have their evening meal before 9 p.m. or wait at least two hours before going to sleep have lower risk of breast and prostate cancer.
Androgen deprivation therapy for the treatment of prostate cancer can lead to loss of muscle and bone mass. In a recent Scandinavian Journal of Medicine & Science in Sport study of elderly patients undergoing the treatment, playing football -- or what's known as soccer in the United States -- over a 5-year period was linked with preserved bone mineral density (BMD) in the neck of the leg's femur.
A new analysis published in the BJS (British Journal of Surgery) indicates that weight loss surgery may affect an individual's risk of developing cancer.
A review of more than 200 studies reveals that olfactory receptors -- proteins that bind to odors that aid the sense of smell -- perform a wide range of mostly unknown functions outside the nose. The function of extra-nasal olfactory receptors has the potential to be used in the diagnosis and treatment of health conditions such as cancer. The article is published in the July issue of Physiological Reviews.