Results from the NRG Oncology clinical study NRG-RTOG 0415 determined that a hypofractionated radiotherapy schedule (H-RT), a treatment schedule that delivers a total dose of radiotherapy over a shorter period of time, is not worse than the conventional radiotherapy schedule (C-RT) in terms of bowel, bladder, sexual, and general quality of life (QOL) as well as anxiety and depression for men with low risk prostate cancer.
In an effort to understand how colibactin, a compound produced by certain strains of E. coli, may be connected to the development of colorectal cancer, Harvard researchers are exploring how the compound damages DNA to produce DNA adducts.
Many men with low-risk prostate cancer who most likely previously would have undergone immediate surgery or radiation are now adopting a more conservative 'active surveillance' strategy, according to an analysis of a new federal database by scientists from Dana-Farber Cancer Institute.
National guidelines in 2010 began advocating conservative management of low-risk prostate cancer with active surveillance or watchful waiting (AS/WW) as an alternative to radiation to the treat the prostate or surgery to remove the entire prostate. This study examined trends in the management of localized prostate cancer among 165,000 men from 2010 to 2015 using data from a national database of cancer statistics.
Researchers from the Icahn School of Medicine at Mount Sinai and Keck School of Medicine at the University of Southern California have developed a novel machine-learning framework that distinguishes between low- and high-risk prostate cancer with more precision than ever before. The framework, described in a Scientific Reports paper published today, is intended to help physicians -- in particular, radiologists -- more accurately identify treatment options for prostate cancer patients, lessening the chance of unnecessary clinical intervention.
Researchers at the University of Michigan Rogel Cancer Center have cataloged circular RNA in multiple cancers and conducted initial research that suggests these stable structures could serve as cancer biomarkers in blood or urine.
An international multidisciplinary study initiated by Melbourne scientists has shown a link between prostate cancer and the uptake of fatty acids by cancer cells. The findings point to a possible therapeutic target for this common cancer.
Computer simulations show for the first time that when a patient has history of an enlarged prostate, tumors in the prostate barely grow at all.
Experts from the universities of Bath and Seville have carried out a series of experiments with which, for the first time, they have been able to characterize the normal electrical activity in PC-3 prostate cancer cells in real time, with a resulting low-frequency electrical pattern between 0.1 and 10 Hertz.
A new compound based on iridium, a rare metal which landed in the Gulf of Mexico 66 million years ago, hooked onto albumin, a protein in blood, can attack the nucleus of cancerous cells when switched on by light, University of Warwick researchers have found.