New research published this week in Experimental Physiology found that in prostate cancer survivors, a moderate bout of exercise kept the cell count of certain type of immune cells at a normal level, suggesting the exercise is safe for prostate cancer survivors. After 24 hours after a moderate bout of cycling, the immune cell count of natural killer (NK) cells, part of the body's first line of defence, had returned to resting levels.
Researchers observe significant decreases nationwide in the number of patients being seen for cancer-related care as the COVID-19 pandemic progressed during the few first months of 2020.
Using data from a study conducted in Montreal between 2005 and 2012, a research team led by Professor Marie-Élise Parent of Institut national de la recherche scientifique (INRS) has shown a link between diet and prostate cancer in the article "Dietary Patterns Are Associated with Risk of Prostate Cancer in a Population-Based Case-Control Study in Montreal, Canada", published in Nutrients in June.
Study reports 98% sensitivity and 97% specificity in recognizing and characterizing prostate cancer using an artificial intelligence (AI) program.
Scientists have uncovered the genomic signature to explain why 18F-FDG imaging performs better than PSMA-targeted imaging for prostate cancer patients with low or no expression of the prostate-specific membrane antigen (PSMA). In a study published in The Journal of Nuclear Medicine, researchers determined that a neuroendocrine gene signature associates with a distinct differential expression of glucose transporters and hexokinase proteins, which allows for a more favorable uptake of 18F-FDG than PSMA-targeted radioligands.
Fighting cancer often means employing a suite of techniques to target the tumor and prevent it from growing and spreading to other parts of the body. It's no small feat -- the American Cancer Society predicts roughly 1.8 million new cases of cancer in the country in 2020, underscoring the need to identify additional ways to outsmart the runaway cells.
When prostate cancer progresses to a more-dangerous metastatic state, it does so by resurrecting dormant molecular mechanisms that had guided the fetal development of the prostate gland but had been subsequently switched off, say scientists from Dana-Farber Cancer Institute. Researchers generated the world's largest epigenomic dataset in prostate biology.
Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases.
Researchers at Baylor College of Medicine reveal for the first time the complete 3-D structure of the active, full-length androgen receptor-coactivator complex as it interacts with DNA.
New research confirms the high impact of PSMA PET/CT in the detection and management of recurrent disease in prostate cancer patients. In initial results from a multicenter trial assessing the impact of 18F-DCFPyL prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT), a PET-directed change in management was observed in two-thirds of patients. The research was presented at the Society of Nuclear Medicine and Molecular Imaging's 2020 Virtual Annual Meeting.