Researchers at Beth Israel Deaconess Medical Center embarked on a study to investigate whether early changes in energy-related metabolites in the blood -- measured shortly after chemotherapy -- could be used to identify patients who developed heart toxicity at a later time.
Researchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify methylation patterns associated with different subtypes of breast cancer, and a subclassification of the group of 'triple negatives,' a breast cancer type typically associated with poor prognosis. In addition, researchers identified changes in DNA methylation associated with the response to docetaxel, a common therapy. The research was led by Dr. Eva González-Suárez, head of the IDIBELL Transformation and Metastasis research group.
Many of the deadliest or most common cancers get the least amount of nonprofit research funding, reports a new Northwestern Medicine study. 'Embarrassing' or stigmatized cancers, like lung and liver, are underfunded. Colon, endometrial, liver and bile duct, cervical, ovarian, pancreatic and lung cancers were all poorly funded compared to how common they are and how many deaths they cause, the study found. In contrast, breast cancer, leukemia, lymphoma and pediatric cancers were all well-funded, respective to their impact on society.
While revealing that metastatic breast cancer cells alter their shape to spread to other regions of the body, researchers develop a mathematical model that can be applied to study similar cellular systems.
A new biomedical research study finds a transcription factor called Slug contributes to breast cell fitness by promoting efficient repair of DNA damage. The absence of Slug leads to unresolved DNA damage and accelerated aging of breast cells.
A new research method to pinpoint the immune cells that recognise cancer could significantly change how we treat the disease.
University of Colorado Cancer Center study published in Breast Journal argues against combined approach: Patients undergoing coordinated breast and gynecologic procedures had a significantly longer length of hospital stay, and higher complication, readmission, and reoperation rates compared with patients who underwent single site surgery.
This new study correlates a proinflamatory diet with the risk of developing colorectal cancer among the Spanish population.
A new reusable device created by the Johns Hopkins University can help women with breast cancer in lower income countries by using carbon dioxide, a widely available and affordable gas, to power a cancer tissue-freezing probe instead of industry-standard argon.
Associate Professor Hamsa Puthalakath's explanation of why some cancers don't respond to treatment with one of the most effective chemotherapy drugs: 5-Fluorouracil (5-FU) has the potential to lead to: a lab test to check for 5-FU resistance, which would reduce unnecessary chemotherapy treatments; a new drug to turn off 5-FU in resistance; and he finds 5-FU resistance is linked to a the protein 'BOK,' the function of which has stumped scientists for decades.