Many of the drugs and therapies available today for treating breast cancer target the cancer cells but tend to neglect the surrounding 'local environment,' which includes surrounding tissues. But cancer cells and their local environment are connected, so both undergo chemical and physical changes during tumor development. During the 62nd Biophysical Society Meeting, researchers will present work exploring the role physical changes within a cancer cells' local environment play in the aggressiveness of breast cancer.
Enhancing the diagnosis of breast cancer is the stated goal of a research team at the German Cancer Research Center (DKFZ) in Heidelberg. The scientists have combined an advanced method of diffusion-weighted MR imaging with intelligent image analysis methods to detect malignant changes in tissues. This method may help avoid many control biopsies following suspicious findings from mammography screening. This advancement holds promise for substantial improvements in the diagnosis of breast cancer.
An MRI breast imaging technique that requires no contrast agent, combined with sophisticated data analysis, could reduce the number of unnecessary breast biopsies, according to a new study.
Many breast cancer patients undergoing mastectomy with or without immediate reconstruction mispredict future satisfaction with aspects of physical and sexual health post-surgery, according to a new study published by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC -- James).
A clinically relevant 'liquid biopsy' test can be used to profile cancer genomes from blood and predict survival outcomes for patients with metastatic triple negative breast cancer (TNBC), according to new research published by a multi-institutional team of researchers with The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James), the Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.
A new article published in npj Genomic Medicine showcases the wide differences in BRCA testing protocols at labs around the world. The article surveyed 86 laboratories around the world about their BRCA testing practices and found that all the labs differed widely in their approach.
The percentage of cancer survivors without health insurance decreased substantially after implementation of the Affordable Care Act (ACA), reports a study in the March issue of Medical Care, published by Wolters Kluwer.
Commercially available prognostic breast cancer tests show significant variation in their abilities to predict disease recurrence, according to a study led by Queen Mary University of London of nearly 800 postmenopausal women.
About 10 years ago, several labs discovered that a gene called MELK is overexpressed, or turned on to a high degree, in many cancer cell types. This evidence has prompted multiple ongoing clinical trials to test whether drugs that inhibit MELK can treat cancer in patients. Now, CSHL researchers report that MELK is not actually involved in cancer. It's a story about how science self-corrects.
A team of researchers from ORNL's Energy and Transportation Science Division is using neutron imaging to study particulate filters that collect harmful emissions in vehicles. A better understanding of how heat treatments and oxidation methods can remove layers of soot and ash from these filters could lead to improved fuel-efficiency.