Melanoma is a particularly difficult cancer to treat once it has metastasized, spreading throughout the body. University of Illinois researchers are using chemistry to find the deadly, elusive malignant cells within a melanoma tumor that hold the potential to spread. Once found, the stemlike metastatic cells can be cultured and screened for their response to a variety of anti-cancer drugs, providing the patient with an individualized treatment plan based on their own cells.
Offering open-access genetic testing for the inherited breast cancers BRCA1 and 2 to Ashkenazi women unaffected by cancer, regardless of their family history, enables the identification of carriers who would otherwise have been missed.
Swiss scientists from the University of Geneva, Switzerland, and the University of Basel have created artificial viruses that can be used to target cancer. These designer viruses alert the immune system and cause it to send killer cells to help fight the tumor. The results, published in the journal Nature Communications, provide a basis for innovative cancer treatments.
In a new study, scientists at the University of Texas at Dallas have found that some types of cancers have more of a sweet tooth than others. 'It has been suspected that many cancer cells are heavily dependent on sugar as their energy supply, but it turns out that one specific type -- squamous cell carcinoma -- is remarkably more dependent,' said Dr. Jung-whan 'Jay' Kim, senior author of the study.
Researchers have discovered a biochemical signaling process that causes densely packed cancer cells to break away from a tumor and spread the disease elsewhere in the body.
Latin-Americans originate from a mix of people with Native-American, European and African ancestry. A new study finds that different types of original Native-American ancestry can be associated to different causes of death. Justo Lorenzo Bermejo and Felix Boekstegers from Heidelberg University in Germany, and their Chilean colleagues report these findings in a new study published May 26, 2017, in PLOS Genetics.
George Washington University researchers, published in the New England Journal of Medicine, find through looking at genetic data sets of presumed cancer-free women who carry BRCA 1/2 variants, the co-occurrence of a rare COMT genetic variant in some women. This research outlines a strategy for looking at large genetic data sets for clues as to why a genetic carrier may never develop the associated diseases.
For patients with advanced cancer, aggressive care -- chemotherapy, mechanical ventilation, acute hospitalizations and intensive care unit admissions -- at the end of life is commonplace. Yet until now, little is known about the relationship between patients' and families' satisfaction with this aggressive care within the last 30 days of life.
Scientists from the Netherlands and Russia designed and tested a new metasurface-based technology for enhancing the local sensitivity of MRI scanners on humans for the first time. The metasurface consists of thin resonant strips arranged periodically. Placed under a patient's head, it provided much higher signals from the local brain region. The results published in Scientific Reports, show that the use of metasurfaces can potentially reduce image acquisition time, thus improving comfort for patients, or acquire higher resolution images for better disease diagnosis.
A new test, based on a patient's epigenetics, could be an accurate and inexpensive way to find and treat those at highest risk of anal cancer -- a disease with growing incidence in women, men who have sex with men (MSM) and people with HIV.