New research led by Queen Mary University of London and St Bartholomew's Hospital has shown that by using a combination of immunotherapy and chemotherapy the body's own immune system can be tuned to attack triple-negative breast cancer, extending survival
Young cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congress in Munich, has highlighted the existence of barriers to the inclusion of 12 to 25-year-olds in both adult and paediatric early phase clinical trials, suggesting a need for more tailored approaches to give this patient population better access to therapeutic innovation.
A new Florida State University College of Medicine study in mice produced results that suggest nicotine exposure in men could lead to cognitive deficits in their children and grandchildren. Further studies will be required to know if the same outcomes seen in mice would apply to humans.
Adding highly refined fiber to processed foods could have negative effects on human health, such as promoting liver cancer, according to a new study by researchers at Georgia State University and the University of Toledo.
Colorectal cancer patients who followed healthy diets had a lower risk of death from colorectal cancer and all causes, even those who improved their diets after being diagnosed.
Including exercise or sport as part of cancer care can significantly improve symptom management, quality of life and fitness during and after treatment, French researchers have concluded in two presentations to be reported at the ESMO 2018 Congress in Munich. Even among patients at highest risk of poor quality of life, exercise can make a difference.
Most people with lung cancer are unaware of the benefits of regular exercise, yet new data show it can significantly reduce fatigue and improve well being. Results of two studies to be presented at the ESMO 2018 Congress in Munich underline the value of exercise, including in patients with advanced or metastatic lung cancer.
Social vulnerability showed to be a major limitation to participation in cancer screening for four tumors types - breast, cervical, colorectal and lung -- according to the French nationwide observational survey, EDIFICE 6. Also, a disbelief in cancer test efficacy among target populations was highlighted as new indicator of the non-uptake of screening, according to results to be presented at the ESMO 2018 Congress.
Immunotherapy has been a major breakthrough in oncology -- but little is known about its safety for HIV-positive cancer patients. A study to be presented at the ESMO 2018 Congress in Munich has now provided data to suggest that treatment with PD-1/PD-L-1 immune checkpoint inhibitors, which target the very system affected by the HIV virus, is feasible in this patient population for whom cancer is currently one of the principal cause of mortality.
Chemotherapy is known to have a negative impact on the reproductive potential of young breast cancer patients. Its effects on women's post-treatment fertility, however, are still poorly understood. A study to be presented at the ESMO 2018 Congress in Munich, has confirmed that natural pregnancies are possible after chemotherapy but that survivors' desire to have children decreases greatly after treatment, calling into question the need for systematic recourse to fertility preservation measures.