On July 27 2020, the US Department of Health and Human Services' (HHS) Health Resources and Services Administration (HRSA) launched a Special Collection of manuscripts across the open-access journals PLOS Medicine and PLOS ONE, highlighting Ryan White HIV/AIDS Program's (RWHAP) innovative approaches for data utilization and engagement of people with HIV who are not in care and not virally suppressed.
In a pilot study of people living with HIV or high levels of cholesterol, Johns Hopkins Medicine researchers found that a six-week course of a cholesterol-lowering medication improved the function of the coronary arteries that provide oxygen to the heart.
A research group at The Institute of Medical Science, The University of Tokyo (IMSUT) using HIV-1-infected cells performed "multiomics" analyses, which are technologies recently developed to comprehensively investigate the features of biological samples.In this study, a hematopoietic stem cell-transplanted humanized mouse model infected with a gene-modified HIV-1 was used to reveal multiple characteristics of HIV-1-producing cells in vivo.
Kidney transplantation from deceased donors with HIV to people living with both HIV and end-stage kidney disease is feasible and safe, investigators supported by the National Institutes of Health have found. Their study demonstrates that the pool of available kidneys for people with HIV can be expanded by including donors with HIV, making more kidneys available for all who are awaiting a transplant.
The method reveals that the lattice, which forms the major structural component of the human immunodeficiency virus (HIV), is dynamic. The discovery of a diffusing lattice made from Gag and GagPol proteins, long considered to be completely static, opens up potential new therapies. Apart from viruses, the method can be applied to study any biomedical structure by tracking molecules moving around in a cell.
Recent studies indicate HIV infection heightens the risk of dental cavities - but a Rutgers researcher has found evidence that the risk of cavities comes not from HIV itself but from a weakened immune system, which could be caused by other diseases.
This report--describing the first national quality improvement collaborative focused on providing culturally affirming care for LGBT people--finds that making primary care practices more LGBT-friendly and inclusive may improve STD and HIV screening rates among this vulnerable population.
Young gay sexual minority men - especially Black and Latino youth - have their first sexual experiences at younger ages, emphasizing a need for comprehensive and inclusive sex education, according to Rutgers researchers.
In an article published in the journal PNAS, NIH researchers report for the first time that ancient viral genes that were once considered 'junk DNA' may play a role in turning stem cells into neurons.
A suite of articles in The Journal of Infectious Diseases contains the first swath of important data from the world's largest study of cardiovascular disease (CVD) prevention in people with HIV.