Smartphones aren't just for selfies anymore. A novel cell phone imaging algorithm developed at FAU can now analyze assays typically evaluated via spectroscopy, a powerful device used in scientific research. Researchers analyzed more than 10,000 images and found that their method consistently outperformed existing algorithms under a wide range of operating field conditions. This technique reduces the need for bulky equipment and increases the precision of quantitative results.
Using HIV genetic data, researchers discovered that transgender women in Los Angeles are at higher risk of being in an HIV transmission network than men who have sex with men. In addition, cisgender men in these clusters should be considered at higher risk for HIV than previously thought.
Harvard engineers and stem cell biologists have developed an injectable sponge-like gel that enhances the production T-cells after a bone marrow transplant.
George Mason University's Yuntao Wu's research team has identified a measurable indicator that could prove instrumental in the fight against HIV. The research recently published in Science Advances, focuses on cofilin, a key protein that regulates cells to mobilize and fight against infection. HIV patients have "significantly lower" levels of cofilin phosphorylation--but by stimulating the T cells with additional therapeutics, researchers could modulate the levels of cofilin activity needed to restore T cell mobility.
The immunotherapy that has revolutionized treatment of many cancers appears to offer similar benefit to cancer patients living with HIV.
Preexposure prophylaxis (PrEP) for HIV is an antiretroviral pill that is over 90 percent effective in preventing HIV acquisition when taken as prescribed. A new Perspective, published in the Feb. 7 issue of the New England Journal of Medicine, examines clinicians' concerns and biases toward prescribing PrEP and suggests strategies to mitigate those biases.
Scientists have revealed how a protein produced by HIV-1 plays a broader role in suppressing the immune system's response to infection than previously thought.
Hahn's lab and an international team of collaborators, found that the CD4 surface protein, which is used by HIV and SIV as the receptor to enter immune cells, is highly variable among wild chimpanzees. Understanding how these viruses are transmitted within and between species may reveal clues for novel vaccine strategies in humans.
Research out of the University of Kentucky has identified a potential pathway by which certain ARV drugs -- commonly given to patients with HIV -- give rise to liver disease.
Scientists funded by the National Institutes of Health have developed a new assay to accurately and easily count the cells that comprise the HIV reservoir, the stubborn obstacle to an HIV cure. This advance will enable researchers who are trying to eliminate the HIV reservoir to clearly understand whether their strategies are working. The research was supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of NIH.