After 'trying on' three placebo methods for the delivery of a rectal microbicide, study participants said they could see all of them - a douche, rectal suppository and fast-dissolving rectal insert - fitting into their daily lives. These results, which also identified the product attributes most important to participants, underscore the importance of developing a range of HIV prevention products for people who practice anal sex.
A series of weekend workshops that integrate strategies for both reducing risky alcohol use and preventing sexually transmitted infections (STIs) led to an increase in safe sex and decrease in drinking among young Black women, according to a new study published in the American Journal of Preventive Medicine.
A recent preclinical study by U.S. Military HIV Research Program (MHRP) researchers showed that an experimental therapy combining a TLR7 agonist and two broadly neutralizing antibodies delayed viral rebound in SHIV-infected macaques after antiretroviral therapy (ART) interruption.
A new study indicates that protein kinases, which initiate the process that erodes the body's immunity, significantly contribute to the immunodeficiency in HIV patients. Drugs that block these protein kinases may offer a solution to treating HIV patients whose immunity is not restored by antiretroviral therapy.
Washington, DC / New Delhi, India - Researchers at CDDEP, in collaboration with leading experts in the field, have produced the "Infectious Diseases in the South-East Asia Region" report, which examines cross-boundary challenges in communicable disease control in countries in the South-and South-East Asia region. The report emphasizes infectious diseases related to other sources of disease burden in the region and communicates overall trends in the health and economic burden they impose.
In a paper for The Lancet, West Virginia University Drs. Sally Hodder and Judith Feinberg state that the opioid and HIV epidemics are intertwined in West Virginia, and therefore should be treated together.
Study looks at COVID-19 effects on engagement in HIV care, HIV medication use, and overall well-being among low-income Black and Latino individuals who have lived with HIV for many years.
despite coordinated national efforts to implement HIV services, the epidemic persists, especially in the South. It also disproportionately impacts marginalized groups, such as Black/African-American and Latinx communities, women, people who use drugs, men who have sex with men, and other sexual and gender minorities. researchers, advocates, and other stakeholders reported on the HIV epidemic response in The Lancet HIV in the USA Series, published online today (https://www.thelancet.com/series/HIVinUSA).
Researchers from the European Molecular Biology Laboratory and Heidelberg University Hospital combine high-resolution imaging to observe the infection process in cell nuclei, opening the door for new therapeutics.
Using venom from a cone snail, a first-of-its-kind study suggests these conotoxins may potentially treat malaria. The study provides important leads toward the development of new and cost-effective anti-adhesion or blockade-therapy drugs aimed at counteracting the pathology of severe malaria. Similarly, mitigation of emerging diseases like COVID-19 also could benefit from conotoxins as potential inhibitors of protein-protein interactions as treatment. Venom peptides from cone snails has the potential to treat myriad diseases using blockage therapies.